Patents by Inventor Ari SILVER

Ari SILVER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Evolutionary models of multiple sequence alignments to predict offspring fitness prior to conception
    Patent number: 10658068
    Abstract: A system, device and method for receiving multiple aligned genetic sequences obtained from genetic samples of multiple organisms of one or more different species. A measure of evolutionary variation may be computed for one or more alleles at each of one or more aligned genetic loci. The aligned genetic loci in the multiple organisms may be derived from one or more common ancestral genetic loci or may be otherwise related. The measure of evolutionary variation may be a function of variation in alleles at corresponding aligned genetic loci in the multiple aligned genetic sequences. One or more likelihoods may be computed that an allele mutation at each of the one or more genetic loci in a simulated virtual progeny will be deleterious based on the measure of evolutionary variation of alleles at the corresponding aligned genetic loci for the multiple organisms.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: May 19, 2020
    Assignee: Ancestry.com DNA, LLC
    Inventors: Nigel Delaney, Ari Silver, Lee Silver
  • EVOLUTIONARY MODELS OF MULTIPLE SEQUENCE ALIGNMENTS TO PREDICT OFFSPRING FITNESS PRIOR TO CONCEPTION
    Publication number: 20160034635
    Abstract: A system, device and method for receiving multiple aligned genetic sequences obtained from genetic samples of multiple organisms of one or more different species. A measure of evolutionary variation may be computed for one or more alleles at each of one or more aligned genetic loci. The aligned genetic loci in the multiple organisms may be derived from one or more common ancestral genetic loci or may be otherwise related. The measure of evolutionary variation may be a function of variation in alleles at corresponding aligned genetic loci in the multiple aligned genetic sequences. One or more likelihoods may be computed that an allele mutation at each of the one or more genetic loci in a simulated virtual progeny will be deleterious based on the measure of evolutionary variation of alleles at the corresponding aligned genetic loci for the multiple organisms.
    Type: Application
    Filed: October 19, 2015
    Publication date: February 4, 2016
    Inventors: Nigel DELANEY, Ari Silver, Lee Silver
  • EVOLUTIONARY MODELS OF MULTIPLE SEQUENCE ALIGNMENTS TO PREDICT OFFSPRING FITNESS PRIOR TO CONCEPTION
    Publication number: 20150363546
    Abstract: A system, device and method for receiving multiple aligned genetic sequences obtained from genetic samples of multiple organisms of one or more different species. A measure of evolutionary variation may be computed for one or more alleles at each of one or more aligned genetic loci. The aligned genetic loci in the multiple organisms may be derived from one or more common ancestral genetic loci or may be otherwise related. The measure of evolutionary variation may be a function of variation in alleles at corresponding aligned genetic loci in the multiple aligned genetic sequences. One or more likelihoods may be computed that an allele mutation at each of the one or more genetic loci in a simulated virtual progeny will be deleterious based on the measure of evolutionary variation of alleles at the corresponding aligned genetic loci for the multiple organisms.
    Type: Application
    Filed: December 12, 2014
    Publication date: December 17, 2015
    Inventors: Nigel DELANEY, Ari SILVER, Lee SILVER