Patents by Inventor Ariadna FERNÁNDEZ-DONIS

Ariadna FERNÁNDEZ-DONIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN
    Publication number: 20240059690
    Abstract: The present invention relates to pyrazolopyrimidine derivatives having dual pharmacological activity towards both the ?2? subunit of the voltage-gated calcium channel and the sigma-1 (?1) receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
    Type: Application
    Filed: May 20, 2021
    Publication date: February 22, 2024
    Inventors: Ariadna FERNANDEZ-DONIS, José-Luis DÍAZ-FERNÁNDEZ, Carmen ALMANSA-ROSALES, Mónica GARCIA-LOPEZ, Joan-Carles FERNANDEZ-COLLADO, Jordi GONZALEZ-GARCIA, Maria GARRIDO-MARTINEZ
  • HOMOPIPERAZINYL AND HOMOPIPERIDINYL QUINAZOLIN-4(3H)-ONE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN
    Publication number: 20220380345
    Abstract: The present invention relates to homopiperazinyl and homopiperidinyl quinazolin-4(3H)-one derivatives having dual pharmacological activity towards both the ?2? subunit of the voltage-gated calcium channel and the sigma-1 (?1) receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
    Type: Application
    Filed: October 5, 2020
    Publication date: December 1, 2022
    Inventors: Carmen ALMANSA-ROSALES, Ariadna FERNANDEZ-DONIS, José-Luís DÍAZ-FERNÁNDEZ, Monica GARCIA-LOPEZ, Sergi RODRIGUEZ-ESCRICH, Ute CHRISTMANN
  • PIPERAZINYL AND PIPERIDINYL QUINAZOLIN-4(3H)-ONE DERIVATIVES HAVING ACTIVITY AGAINST PAIN
    Publication number: 20220002314
    Abstract: The present invention relates to piperazinyl and piperidinyl quinazolin-4(3H)-one derivatives having pharmacological activity towards the ?2? subunit, in particular the ?2?-1 subunit, of the voltage-gated calcium channel, in particular having dual pharmacological activity towards both the ?2? subunit, in particular the ?2?-1 subunit, of the voltage-gated calcium channel and the ?-opioid receptor. The present invention also relates to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
    Type: Application
    Filed: October 31, 2019
    Publication date: January 6, 2022
    Applicant: ACONDICIONAMIENTO TARRASENSE
    Inventors: Ariadna FERNÁNDEZ-DONIS, Jose Luís DÍAZ-FERNÁNDEZ, Carmen ALMANSA-ROSALES, Adriana LORENTE-CRIVILLÉ
  • (HETERO)ARYLALKYLAMINO-PYRAZOLOPYRIDAZINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN
    Publication number: 20200199127
    Abstract: The present invention relates to (hetero)arylalkylamino-pyrazolopyridazine derivatives having dual pharmacological activity towards both the ?2? subunit, in particular the ?2?-1 subunit, of the voltage-gated calcium channel and the Noradrenaline transporter (NET), to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
    Type: Application
    Filed: May 29, 2018
    Publication date: June 25, 2020
    Inventors: Susana YENES-MINGUEZ, Ariadna FERNANDEZ-DONIS, Carmen ALMANSA-ROSALES
  • SUBSTITUTED PYRROLIDINYL AND PIPERIDINYL PYRAZOLOPYRIDAZINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN
    Publication number: 20200062767
    Abstract: The present invention relates to substituted pyrrolidinyl and piperidinyl pyrazolopyridazine derivatives having dual pharmacological activity towards both the ?2? subunit, in particular the ?2??1 subunit, of the voltage-gated calcium channel and the Noradrenaline transporter (NET), to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
    Type: Application
    Filed: May 29, 2018
    Publication date: February 27, 2020
    Inventors: Carmen ALMANSA-ROSALES, José-Luís DÍAZ-FERNÁNDEZ, Ariadna FERNANDEZ-DONIS, Susana YENES-MINGUEZ