Abstract: Provided is a method, a device and a positioning system for positioning a sensor at an optimized position for optimized monitoring of a technical system. The method includes providing a physical simulation model of the technical system, wherein the physical simulation model includes a virtual sensor at a given position, simulating a performance of the technical system by the physical simulation model, providing a response signal of the virtual sensor to the simulated performance at the given position, determining a first optimized position for the virtual sensor where the response signal is intensified by an optimization algorithm, and providing co-ordinates of the first optimized position for positioning a physical sensor at the technical system.