Patents by Inventor Aribert Stief

Aribert Stief has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Attachment-elements for stimulation of eukaryotic expression systems
    Patent number: 5731178
    Abstract: The invention concerns methods to increase the expression of genes brought into eukaryotic cells or organisms. By flanking a transcription unit EPC made up by e.g. an enhancer (E), promoter (P), and the (structural) gene of interest (C) with attachment-elements (A) the expression of said (structural) gene of interest is stimulated when integrated into the genome of eucaryotic cells and is independent of its chromosomal position. Thus a construct AEPCA is advantageous because it constitutes an independant regulatory unit.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: March 24, 1998
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Albrecht E. Sippel, Aribert Stief