Patents by Inventor Arie Shteyer

Arie Shteyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic peptides and pseudopeptides having osteogenic activity and pharmaceutical compositions containing the same
    Patent number: 7189692
    Abstract: Cyclic to Synthetic pseudopeptide derivatives of osteogenic growth polypeptide (OGP) and OGP(10-14) which are capable of enhancing bone cell proliferation and bone formation. Pharmaceutical composition comprising as active ingredient at least one pseudopeptide derivative of the invention and to the use of these pseudopeptide derivatives in the preparation of a pharmaceutical composition for stimulating the formation of osteoblastic or fibroblastic cells, enhancing bone formation in osteopenic pathological conditions, repairing fractures, healing wounds, grafting of intraosseous implants, reversing bone loss in osteoporosis and other conditions requiring enhanced bone cells formation.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: March 13, 2007
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Itai Bab, Dan Gazit, Chen Yu-Chen, Andras Muhlrad, Arie Shteyer, Michael Chorev
  • Synthetic peptides and pseudopeptides having osteogenic activity and pharmaceutical compositions containing the same
    Publication number: 20030069175
    Abstract: Cyclic to Synthetic pseudopeptide derivatives of osteogenic growth polypeptide (OGP) and OGP(10-14) which are capable of enhancing bone cell proliferation and bone formation. Pharmaceutical composition comprising as active ingredient at least one pseudopeptide derivative of the invention and to the use of these pseudopeptide derivatives in the preparation of a pharmaceutical composition for stimulating the formation of osteoblastic or fibroblastic cells, enhancing bone formation in osteopenic pathological conditions, repairing fractures, healing wounds, grafting of intraosseous implants, reversing bone loss in osteoporosis and other conditions requiring enhanced bone cells formation.
    Type: Application
    Filed: September 27, 2002
    Publication date: April 10, 2003
    Inventors: Itai Bab, Dan Gazit, Chen Yu-Chen, Andras Muhlrad, Arie Shteyer, Michael Chorev
  • Synthetic peptides and pseudopeptides having osteogenic activity and pharmaceutical compositions containing the same
    Patent number: 6479460
    Abstract: The invention relates to synthetic pseudopeptide derivatives of osteogenic grog polypeptide (OGP) and OGP(10-14) which may be linear or cyclic, and which are capable of enhancing bone cell proliferation and bone formation. Further, the present invention relates to pharmaceutical composition comprising as active ingredient at least one pseudopeptide derivative of the invention and to the use of these pseudopeptide derivatives in the preparation of a pharmaceutical composition for stimulating the formation of osteoblastic or fibroblastic cells, enhancing bone formation in osteopenic pathological conditions, repairing fractures, healing wounds, grafting of intraosseous implants, reversing bone loss in osteoporosis and other conditions requiring enhanced bone cells formation.
    Type: Grant
    Filed: September 10, 1998
    Date of Patent: November 12, 2002
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Itai Bab, Dan Gazit, Chen Yu-Chen, Andras Muhlrad, Arie Shteyer, Michael Chorev
  • Osteogenic growth oligopeptides and pharmaceutical compositions containing them
    Patent number: 5814610
    Abstract: The invention relates to biochemically pure oligopeptides having stimulatory activity on osteoblastic and/or fibroblastic cells having a molecular weight between 200 and 2,000. Preferred oligopeptides according to the invention comprise the amino acid sequences Tyr-Gly-Phe-His-Gly (SEQ.ID.No.2) and Gly-Phe-Gly-Gly (SEQ.ID.No.3). The invention further relates to pharmaceutical compositions for the stimulation of formation of osteoblastic or fibroblastic cells, enhanced bone formation in osteogenic pathological conditions, fracture repair, healing of wounds, intraosseous implants and bone supplementation, or other conditions requiring enhanced bone formation cells comprising a therapeutically effective amount of an oligopeptide according to the invention.
    Type: Grant
    Filed: January 5, 1996
    Date of Patent: September 29, 1998
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Itai Bab, Andras Muhlrad, Michael Chorev, Arie Shteyer, Zvi Greenberg, Nura Mansur