Abstract: A method of using a biological sampling device to obtain a biological sample. The device comprises a sheath, an applicator, a collector, and a handle. The method includes inserting a first applicator end into an organism with the device being in a pre-sampling configuration; transitioning the device from the pre-sampling configuration to a sampling configuration; with the device in the sampling configuration, via the handle, moving the collector against biological material within the organism to collect the biological material; transitioning the device from the sampling configuration to a post-sampling configuration; and with the device in the post-sampling configuration, withdrawing the device from within the organism.

Abstract: A method of using a biological sampling device to obtain a biological sample. The device comprises a sheath, an applicator, a collector, and a handle. The method includes inserting a first applicator end into an organism with the device being in a pre-sampling configuration; transitioning the device from the pre-sampling configuration to a sampling configuration; with the device in the sampling configuration, via the handle, moving the collector against biological material within the organism to collect the biological material; transitioning the device from the sampling configuration to a post-sampling configuration; and with the device in the post-sampling configuration, withdrawing the device from within the organism.

Abstract: A method of using a biological sampling device to obtain a biological sample. The device comprises a sheath, an applicator, a collector, and a handle. The method includes inserting a first applicator end into an organism with the device being in a pre-sampling configuration; transitioning the device from the pre-sampling configuration to a sampling configuration; with the device in the sampling configuration, via the handle, moving the collector against biological material within the organism to collect the biological material; transitioning the device from the sampling configuration to a post-sampling configuration; and with the device in the post-sampling configuration, withdrawing the device from within the organism.

Abstract: A method of using a biological sampling device to obtain a biological sample. The device comprises a sheath, an applicator, a collector, and a handle. The method includes inserting a first applicator end into an organism with the device being in a pre-sampling configuration; transitioning the device from the pre-sampling configuration to a sampling configuration; with the device in the sampling configuration, via the handle, moving the collector against biological material within the organism to collect the biological material; transitioning the device from the sampling configuration to a post-sampling configuration; and with the device in the post-sampling configuration, withdrawing the device from within the organism.

Abstract: A biological sampling device for collecting biological material from within an organism can include a sheath, a collector, a handle, and optionally, an applicator. In a secured position, a collector is within the sheath and/or applicator; in a sampling position, a collector is outside the sheath and applicator. A device can be inserted into an orifice of an organism with a collector being transitioned from a secured to a sampling position, moved via a handle to collect biological material for testing, and subsequently returned to a secured position. A biological sample can be prepared from biological material collected by a biological sampling device, and a biological sample can be tested by application of a testing protocol.