Patents by Inventor Arina Corli HITZEROTH

Arina Corli HITZEROTH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of polypeptides relevant to human and animal health using
    Patent number: 9963487
    Abstract: The present invention relates to the expression of polypeptides using Yarrowia lipolytica, in particular the secretion of expressed polypeptides into either the extracellular space or the surface of the Y. lipolytica host cell wall. The invention also extends to the use of the polypeptides so expressed in biotechnological applications. The present invention provides an expression construct for the expression of polypeptides using at least a single Yarrowia lipolytica yeast cell, the expression construct having at least one expression cassette, the expression cassette including an acid extracellular protease secretion signal sequence and flanking zeta sequence recombination sites.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: May 8, 2018
    Assignee: UNIVERSITY OF THE FREE STATE
    Inventors: Robert Richard Bragg, Charlotte Enastacia Boucher, Chrispian William Theron, Arina Corli Hitzeroth
  • Production of polypeptides relevant to human and animal health using
    Patent number: 9908917
    Abstract: The present invention relates to the expression of polypeptides using Yarrowia lipolytica, in particular the secretion of expressed polypeptides into either the extracellular space or the surface of the Y. lipolytica host cell wall. The invention also extends to the use of the polypeptides so expressed in biotechnological applications. The present invention provides an expression construct for the expression of polypeptides using at least a single Yarrowia lipolytica yeast cell, the expression construct having at least one expression cassette, the expression cassette including an acid extracellular protease secretion signal sequence and flanking zeta sequence recombination sites.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: March 6, 2018
    Assignee: UNIVERSITY OF THE FREE STATE
    Inventors: Robert Richard Bragg, Charlotte Enastacia Boucher, Chrispian William Theron, Arina Corli Hitzeroth
  • Production of Polypeptides Relevant to Human and Animal Health Using Yarrowia lipolytica
    Publication number: 20170002044
    Abstract: The present invention relates to the expression of polypeptides using Yarrowia lipolytica, in particular the secretion of expressed polypeptides into either the extracellular space or the surface of the Y. lipolytica host cell wall. The invention also extends to the use of the polypeptides so expressed in biotechnological applications. The present invention provides an expression construct for the expression of polypeptides using at least a single Yarrowia lipolytica yeast cell, the expression construct having at least one expression cassette, the expression cassette including an acid extracellular protease secretion signal sequence and flanking zeta sequence recombination sites.
    Type: Application
    Filed: September 15, 2016
    Publication date: January 5, 2017
    Inventors: Robert Richard BRAGG, Charlotte Enastacia BOUCHER, Chrispian William THERON, Arina Corli HITZEROTH
  • Production of Polypeptides Relevant to Human and Animal Health Using Yarrowia lipolytica
    Publication number: 20160090601
    Abstract: The present invention relates to the expression of polypeptides using Yarrowia lipolytica, in particular the secretion of expressed polypeptides into either the extracellular space or the surface of the Y. lipolytica host cell wall. The invention also extends to the use of the polypeptides so expressed in biotechnological applications. The present invention provides an expression construct for the expression of polypeptides using at least a single Yarrowia lipolytica yeast cell, the expression construct having at least one expression cassette, the expression cassette including an acid extracellular protease secretion signal sequence and flanking zeta sequence recombination sites.
    Type: Application
    Filed: September 30, 2015
    Publication date: March 31, 2016
    Inventors: Robert Richard BRAGG, Charlotte Enastacia BOUCHER, Chrispian William THERON, Arina Corli HITZEROTH