Patents by Inventor Ariosa Diagnostics, Inc.

Ariosa Diagnostics, Inc. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MATHEMATICAL NORMALIZATION OF SEQUENCE DATA SETS
    Publication number: 20140095136
    Abstract: The invention provides processes of the present invention provide normalization procedures for sequences within multiplexed data sets using the sequence information from multiplexed sequencing data set itself rather than the utilization of any external references.
    Type: Application
    Filed: December 17, 2012
    Publication date: April 3, 2014
    Applicant: ARIOSA DIAGNOSTICS, INC.
    Inventor: ARIOSA DIAGNOSTICS, INC.
  • ASSAY SYSTEMS FOR GENETIC ANALYSIS
    Publication number: 20130210640
    Abstract: The present invention provides assay systems and methods for detection of copy number variation at one or more loci and polymorphism detection at one or more loci in a mixed sample from an individual.
    Type: Application
    Filed: March 8, 2013
    Publication date: August 15, 2013
    Applicant: ARIOSA DIAGNOSTICS, INC.
    Inventor: ARIOSA DIAGNOSTICS, INC.
  • NONINVASIVE DETECTION OF FETAL ANEUPLOIDY IN EGG DONOR PREGNANCIES
    Publication number: 20130178371
    Abstract: The present invention provides assay systems and methods for determining the percent fetal contribution of cell-free DNA in a maternal sample from a pregnant female with an egg donor pregnancy. Further provided, are assay systems and methods for determining a statistical likelihood of the presence or absence of a fetal aneuploidy in a maternal sample using a determined percent fetal cell-free DNA in the sample.
    Type: Application
    Filed: December 19, 2012
    Publication date: July 11, 2013
    Applicant: ARIOSA DIAGNOSTICS, INC.
    Inventor: ARIOSA DIAGNOSTICS, INC.
  • LIGATION-BASED DETECTION OF GENETIC VARIANTS
    Publication number: 20130172213
    Abstract: The present invention provides assays systems and methods for detection of genetic variants in a sample, including copy number variation and single nucleotide polymorphisms. The invention preferably employs the technique of tandem ligation, i.e. the ligation of two or more fixed sequence oligonucleotides and one or more bridging oligonucleotides complementary to a region between the fixed sequence oligonucleotides.
    Type: Application
    Filed: March 8, 2013
    Publication date: July 4, 2013
    Applicant: ARIOSA DIAGNOSTICS, INC.
    Inventor: Ariosa Diagnostics, Inc.
  • LIGATION-BASED DETECTION OF GENETIC VARIANTS
    Publication number: 20130172211
    Abstract: The present invention provides assays systems and methods for detection of genetic variants in a sample, including copy number variation and single nucleotide polymorphisms. The invention preferably employs the technique of tandem ligation, i.e. the ligation of two or more fixed sequence oligonucleotides and one or more bridging oligonucleotides complementary to a region between the fixed sequence oligonucleotides.
    Type: Application
    Filed: March 8, 2013
    Publication date: July 4, 2013
    Applicant: ARIOSA DIAGNOSTICS, INC.
    Inventor: Ariosa Diagnostics, Inc.
  • LIGATION-BASED DETECTION OF GENETIC VARIANTS
    Publication number: 20130172212
    Abstract: The present invention provides assays systems and methods for detection of genetic variants in a sample, including copy number variation and single nucleotide polymorphisms. The invention preferably employs the technique of tandem ligation, i.e. the ligation of two or more fixed sequence oligonucleotides and one or more bridging oligonucleotides complementary to a region between the fixed sequence oligonucleotides.
    Type: Application
    Filed: March 8, 2013
    Publication date: July 4, 2013
    Applicant: ARIOSA DIAGNOSTICS, INC.
    Inventor: Ariosa Diagnostics, Inc.
  • DETECTION OF GENETIC ABNORMALITIES
    Publication number: 20130143213
    Abstract: The present invention provides assay systems and related methods for determining genetic abnormalities in mixed samples comprising cell free DNA from both normal and putative genetically atypical cells. Exemplary mixed samples for analysis using the assay systems of the invention include samples comprising both maternal and fetal cell free DNA and samples that contain DNA from normal cells and circulating cancerous cells.
    Type: Application
    Filed: November 29, 2012
    Publication date: June 6, 2013
    Applicant: ARIOSA DIAGNOSTICS, INC.
    Inventor: Ariosa Diagnostics, Inc.
  • ASSAY SYSTEMS FOR GENETIC ANALYSIS
    Publication number: 20130122500
    Abstract: The present invention provides assay systems and methods for detection of copy number variation at one or more loci and polymorphism detection at one or more loci in a mixed sample from an individual.
    Type: Application
    Filed: November 28, 2012
    Publication date: May 16, 2013
    Applicant: ARIOSA DIAGNOSTICS, INC.
    Inventor: ARIOSA DIAGNOSTICS, INC.
  • RISK CALCULATION FOR EVALUATION OF FETAL ANEUPLOIDY
    Publication number: 20130089863
    Abstract: The present invention provides processes for determining accurate risk probabilities for fetal aneuploidies. Specifically, the invention provides non-invasive evaluation of genomic variations through chromosome-selective sequencing and non-host fraction data analysis of maternal samples.
    Type: Application
    Filed: November 29, 2012
    Publication date: April 11, 2013
    Applicant: ARIOSA DIAGNOSTICS, INC.
    Inventor: Ariosa Diagnostics, Inc.