Abstract: A magnesium sulfate-based desiccant comprising powder composed of coated particles that contain a particle of magnesium sulfate represented by the chemical formula MgSO4.nH2O (0?n?3) and a coating layer on the surface of the particle, wherein: (1) the coating layer contains a coating material that is at least one of carboxylic acids and salts thereof; (2) the powder has an average particle diameter of 5 ?m or less; and (3) a contact angle of water relative to the face formed with the powder is 20 degrees or more, and to a method for producing the same.

Abstract: The present invention provides a core particle for a pharmaceutical preparation which features the requisite properties of a core particle, and which has enough chemical stability, and in which reactivity with the drug (an active pharmaceutical ingredient) is limited or prevented. More specifically, the present invention relates to a core particle wherein a film containing an active pharmaceutical ingredient can be formed on the surface thereof, and (1) the core particle comprises a pharmaceutically acceptable inorganic material, (2) the inorganic material is poorly soluble in water, and (3) pH of a solution of the inorganic material is 5 to 8.

Abstract: The present invention is to provide a magnesium sulfate-based desiccant comprising powder composed of coated particles that contain a particle of magnesium sulfate represented by the chemical formula MgSO4.nH2O (0?n?3) and a coating layer on the surface of the particle, wherein: (1) the coating layer contains a coating material that is at least one of carboxylic acids and salts thereof; (2) the powder has an average particle diameter of 5 ?m or less; and (3) a contact angle of water relative to the face formed with the powder is 20 degrees or more, and to a method for producing the same.

Abstract: Provided is a core particle for a pharmaceutical preparation, capable of delivering a relatively large amount of a drug active ingredient, in particular, at a predetermined timing. This invention relates to a disintegrable core particle for a pharmaceutical preparation, which core particle is adapted for formation, on the particle surface, of a drug active ingredient-containing film, wherein (1) the core particle includes a pharmaceutically acceptable inorganic material and a disintegration promoting agent, (2) the inorganic material is poorly soluble in water, (3) the inorganic material has a content of from 50 to 95 wt %, and (4) the core particle has a bulk density of at least 0.6 g/mL.

Abstract: Provided is a magnesium oxide for pharmaceutical use that, when mixed with a drug that is unstable in acid, demonstrates high stabilizing effects on the drug while also demonstrating superior stability of the magnesium oxide per se. The magnesium oxide for pharmaceutical use is used by being mixed with a drug that is unstable in acid, and has a specific surface area as determined according to the BET method of 20 m2/g to 200 m2/g and a degree of activation of 40 Img/g to 200 Img/g.

Abstract: The present invention provides a core particle for a pharmaceutical preparation which features the requisite properties of a core particle, and which has enough chemical stability, and in which reactivity with the drug (an active pharmaceutical ingredient) is limited or prevented. More specifically, the present invention relates to a core particle wherein a film containing an active pharmaceutical ingredient can be formed on the surface thereof, and (1) the core particle comprises a pharmaceutically acceptable inorganic material, (2) the inorganic material is poorly soluble in water, and (3) pH of a solution of the inorganic material is 5 to 8.