Patents by Inventor Arja Mantyla

Arja Mantyla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7927849
    Abstract: The present invention relates to a novel laccase enzyme obtainable from the strains of genus Thielavia. The invention relates also to the nucleic acid sequence encoding the enzyme, a recombinant host into which the nucleic acid sequence has been introduced and a method for the production of the enzyme in a recombinant host. The enzyme of the invention is suitable for several applications, in particular for increasing the lightness of denim.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: April 19, 2011
    Assignee: AB Enzymes OY
    Inventors: Marja Paloheimo, Leena Valtakari, Terhi Puranen, Kristiina Kruus, Jarno Kallio, Arja Mantyla, Richard Fagerstrom, Pentti Ojapalo, Jari Vehmaanpera
  • Patent number: 7816129
    Abstract: The present invention is related to an improved production of bacterial proteins in filamentous fungus, e.g. in Trichoderma and Aspergillus. The improvement is achieved by constructing expression vectors, which comprise the bacterial protein encoding DNA sequences fused in frame with a DNA sequence encoding a filamentous fungus secretable protein or one or more functional domains of said protein. Filamentous fungus hosts transformed with such expression vectors secrete the desired proteins or enzymes, especially xylanases or cellulases originating from bacteria or more preferably from actinornycetes into the culture medium of the host. The desired proteins or enzymes can be used directly from the culture medium after separation of host cells or recovered and treated using down-stream processes, which are appropriate for the respective application. Xylanases or cellulases from actinomycetes produced using the above expression vectors are most suitable for treating plant derived materials e.g.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: October 19, 2010
    Assignee: AB Enzymes GmbH
    Inventors: Arja Mäntylä, Marja Paloheimo, Raija Lantto, Richard Fagerström, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanperä
  • Patent number: 7732178
    Abstract: The present invention relates to novel laccase enzymes obtainable from the strains of the genus Thielavia or from the strains of the genus Chaetomium. The invention relates also to nucleic acid sequences encoding the enzymes, recombinant hosts into which the nucleic acid sequences have been introduced and to methods for the production of the enzymes in recombinant hosts. The enzymes of the invention are suitable for several applications, for example for treating denim and for strain removal.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: June 8, 2010
    Assignee: AB Enzymes Oy
    Inventors: Marja Paloheimo, Terhi Puranen, Leena Valtakari, Kristiina Kruus, Jarno Kallio, Arja Mantyla, Richard Fagerstrom, Pentti Ojapalo, Jari Vehmaanpera
  • Publication number: 20080248016
    Abstract: The present invention relates to novel laccase enzymes obtainable from the strains of the genus Thielavia or from the strains of the genus Chaetomium. The invention relates also to nucleic acid sequences encoding the enzymes, recombinant hosts into which the nucleic acid sequences have been introduced and to methods for the production of the enzymes in recombinant hosts. The enzymes of the invention are suitable for several applications, for example for treating denim and for strain removal.
    Type: Application
    Filed: September 21, 2005
    Publication date: October 9, 2008
    Applicant: AB ENZYMES OY
    Inventors: Marja Paloheimo, Terhi Puranen, Leena Valtakari, Kristiina Kruus, Jarno Kallio, Arja Mantyla, Richard Fagerstrom, Pentti Ojapalo, Jari Vehmaanpera
  • Patent number: 7348172
    Abstract: The invention is related to a method and DNA constructs for obtaining in a filamentous fungus host a higher production level of a carbohydrate degrading (CD) enzyme, having in its original state a catalytic module (CAT) and a carbohydrate binding module (CBM) separated by a linker region. The DNA construct comprising a truncated actinomycetes, preferably Nonomuraea flexuosa (NJ) derived DNA sequence encoding a truncated form of the CD enzyme, for example Nf Xyn11A, Nf Xyn10A, and is introduced into a filamentous fungal host. Said CD enzyme contains the catalytically active region of CAT but lacks part or all of the CBM, or all of the CBM and part or all of the linker region and is expressed and secreted under the control of regulatory sequences comprising at least a signal sequence, but also promoters, terminators and DNA sequences encoding a secretable carrier protein or domains thereof, preferably originating from filamentous fungi are included.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: March 25, 2008
    Assignee: AB Enzymes Oy
    Inventors: Marja Paloheimo, Arja Mantyla, Sanna Leskinen, Richard Fagerstrom, Jarno Kallio, Terhi Puranen, Raija Lantto, Pirkko Suominen
  • Patent number: 7323326
    Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
    Type: Grant
    Filed: February 20, 2004
    Date of Patent: January 29, 2008
    Assignee: AB Enzymes Oy
    Inventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanpera, Heli Haakana, Arja Mantyla, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
  • Patent number: 7273748
    Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: September 25, 2007
    Assignee: AB Enzymes Oy
    Inventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanpera, Heli Haakana, Arja Mantyla, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
  • Publication number: 20060063246
    Abstract: The present invention relates to a novel laccase enzyme obtainable from the strains of genus Thielavia. The invention relates also to the nucleic acid sequence encoding the enzyme, a recombinant host into which the nucleic acid sequence has been introduced and a method for the production of the enzyme in a recombinant host. The enzyme of the invention is suitable for several applications, in particular for increasing the lightness of denim.
    Type: Application
    Filed: September 21, 2005
    Publication date: March 23, 2006
    Applicant: AB Enzymes OY
    Inventors: Marja Paloheimo, Leena Valtakari, Terhi Puranen, Kristiina Kruus, Jarno Kallio, Arja Mantyla, Richard Fagerstrom, Pentti Ojapalo, Jari Vehmaanpera
  • Publication number: 20060014247
    Abstract: The invention is related to a method and DNA constructs for obtaining in a filamentous fungus host a higher production level of a carbohydrate degrading (CD) enzyme, having in its original state a catalytic module (CAT) and a carbohydrate binding module (CBM) separated by a linker region. The DNA construct comprising a truncated actinomycetes, preferably Nonomuraea flexuosa (NJ) derived DNA sequence encoding a truncated form of the CD enzyme, for example Nf Xyn11A, Nf Xyn10A, and is introduced into a filamentous fungal host. Said CD enzyme contains the catalytically active region of CAT but lacks part or all of the CBM, or all of the CBM and part or all of the linker region and is expressed and secreted under the control of regulatory sequences comprising at least a signal sequence, but also promoters, terminators and DNA sequences encoding a secretable carrier protein or domains thereof, preferably originating from filamentous fungi are included.
    Type: Application
    Filed: April 18, 2005
    Publication date: January 19, 2006
    Inventors: Marja Paloheimo, Arja Mantyla, Sanna Leskinen, Richard Fagerstrom, Jarno Kallio, Terhi Puranen, Raija Lantto, Pirkko Suominen
  • Publication number: 20040185498
    Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
    Type: Application
    Filed: April 16, 2004
    Publication date: September 23, 2004
    Inventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanpera, Heli Haakana, Arja Mantyla, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
  • Publication number: 20040142444
    Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
    Type: Application
    Filed: February 20, 2004
    Publication date: July 22, 2004
    Inventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanpera, Heli Haakana, Arja Mantyla, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
  • Patent number: 6723549
    Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
    Type: Grant
    Filed: April 30, 1997
    Date of Patent: April 20, 2004
    Assignee: AB Enzymes Oy
    Inventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanperä, Heli Haakana, Arja Mäntylä, Raija Lanto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
  • Patent number: 6667170
    Abstract: The production of thermostable xylanses having bacterial origin is described. These compositions are useful for modifying plant biomass and for enzyme-aided bleaching of wood pulp.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: December 23, 2003
    Assignee: Röhm Enzyme Finland Oy
    Inventors: Arja Mäntylä, Marja Paloheimo, Raija Lantto, Richard Fagerström, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanperä
  • Patent number: 6635464
    Abstract: DNA encoding novel xylanases, vectors containing such DNA, hosts transformed with such DNA, enzyme preparations, and the use of such preparations are described.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: October 21, 2003
    Assignee: Rohm Enzyme Finland OY
    Inventors: Marja Paloheimo, Satu Hakola, Arja Mantyla, Jari Vehmaanpera, Raija Lantto, Tarja Lahtinen, Richard Fagerström, Pirkko Suominen
  • Publication number: 20030148453
    Abstract: The present invention is related to an improved production of bacterial proteins in filamentous fungus, e.g. in Tfichodenna and Aspergillus. The improvement is achieved by constructing expression vectors, which comprise the bacterial protein encoding DNA sequences fused in frame with a DNA sequence encoding a filamentous fungus secretable protein or one or more functional domains of said protein. Filamentous fungus hosts transformed with such expression vectors secrete the desired proteins or enzymes, especially xylanases or cellulases originating from bacteria or more preferably from actinornycetes into the culture medium of the host. The desired proteins or enzymes can be used directly from the culture medium after separation of host cells or recovered and treated using down-stream processes, which are appropriate for the respective application. Xylanases or cellulases from actinomycetes produced using the above expression vectors are most suitable for treating plant derived materials e.g.
    Type: Application
    Filed: August 13, 2002
    Publication date: August 7, 2003
    Applicant: Rohm Enzyme Finland Oy
    Inventors: Arja Mantyla, Marja Paloheimo, Raija Lantto, Richard Fagerstrom, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanpera
  • Patent number: 6506593
    Abstract: The production of thermostable xylanses having bacterial origin is described. These compositions are useful for modifying plant biomass and for enzyme-aided bleaching of wood pulp.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: January 14, 2003
    Assignee: Rohm Enzyme Finland OY
    Inventors: Arja Mäntylä, Marja Paloheimo, Raija Lantto, Richard Fagerström, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanperä
  • Publication number: 20020168751
    Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
    Type: Application
    Filed: April 30, 1997
    Publication date: November 14, 2002
    Inventors: ARJA MIETTINEN-OINONEN, JOHN LONDESBOROUGH, JARI VEHMAANPERA, HELI HAAKANA, ARJA MANTYLA, RAIJA LANTTO, MINNA ELOVAINIO, VESA JOUTSJOKI, MARJA PALOHEIMO, PIRKKO SUOMINEN
  • Publication number: 20010024815
    Abstract: The production of thermostable xylanses having bacterial origin is described. These compositions are useful for modifying plant biomass and for enzyme-aided bleaching of wood pulp.
    Type: Application
    Filed: January 29, 2001
    Publication date: September 27, 2001
    Inventors: Arja Mantyla, Marja Paloheimo, Raija Lantto, Richard Fagerstrom, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanpera
  • Patent number: 6228629
    Abstract: DNA encoding novel xylanases, vectors containing such DNA, hosts transformed with such DNA, enzyme preparations, and the use of such preparations are described.
    Type: Grant
    Filed: December 17, 1996
    Date of Patent: May 8, 2001
    Assignee: Röhn Enzyme Finland OY
    Inventors: Marja Paloheimo, Satu Hakola, Arja Mäntylä, Jari Vehmaanperä, Raija Lantto, Tarja Lahtinen, Richard B. Fagerström, Pirkko Suominen
  • Patent number: 6184019
    Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: February 6, 2001
    Assignee: Röhm Enzyme Finland OY
    Inventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanperä, Heli Haakana, Arja Mäntylä, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen