Patents by Inventor Arja Mantyla
Arja Mantyla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7927849Abstract: The present invention relates to a novel laccase enzyme obtainable from the strains of genus Thielavia. The invention relates also to the nucleic acid sequence encoding the enzyme, a recombinant host into which the nucleic acid sequence has been introduced and a method for the production of the enzyme in a recombinant host. The enzyme of the invention is suitable for several applications, in particular for increasing the lightness of denim.Type: GrantFiled: September 21, 2005Date of Patent: April 19, 2011Assignee: AB Enzymes OYInventors: Marja Paloheimo, Leena Valtakari, Terhi Puranen, Kristiina Kruus, Jarno Kallio, Arja Mantyla, Richard Fagerstrom, Pentti Ojapalo, Jari Vehmaanpera
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Patent number: 7816129Abstract: The present invention is related to an improved production of bacterial proteins in filamentous fungus, e.g. in Trichoderma and Aspergillus. The improvement is achieved by constructing expression vectors, which comprise the bacterial protein encoding DNA sequences fused in frame with a DNA sequence encoding a filamentous fungus secretable protein or one or more functional domains of said protein. Filamentous fungus hosts transformed with such expression vectors secrete the desired proteins or enzymes, especially xylanases or cellulases originating from bacteria or more preferably from actinornycetes into the culture medium of the host. The desired proteins or enzymes can be used directly from the culture medium after separation of host cells or recovered and treated using down-stream processes, which are appropriate for the respective application. Xylanases or cellulases from actinomycetes produced using the above expression vectors are most suitable for treating plant derived materials e.g.Type: GrantFiled: August 13, 2002Date of Patent: October 19, 2010Assignee: AB Enzymes GmbHInventors: Arja Mäntylä, Marja Paloheimo, Raija Lantto, Richard Fagerström, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanperä
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Patent number: 7732178Abstract: The present invention relates to novel laccase enzymes obtainable from the strains of the genus Thielavia or from the strains of the genus Chaetomium. The invention relates also to nucleic acid sequences encoding the enzymes, recombinant hosts into which the nucleic acid sequences have been introduced and to methods for the production of the enzymes in recombinant hosts. The enzymes of the invention are suitable for several applications, for example for treating denim and for strain removal.Type: GrantFiled: September 21, 2005Date of Patent: June 8, 2010Assignee: AB Enzymes OyInventors: Marja Paloheimo, Terhi Puranen, Leena Valtakari, Kristiina Kruus, Jarno Kallio, Arja Mantyla, Richard Fagerstrom, Pentti Ojapalo, Jari Vehmaanpera
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Publication number: 20080248016Abstract: The present invention relates to novel laccase enzymes obtainable from the strains of the genus Thielavia or from the strains of the genus Chaetomium. The invention relates also to nucleic acid sequences encoding the enzymes, recombinant hosts into which the nucleic acid sequences have been introduced and to methods for the production of the enzymes in recombinant hosts. The enzymes of the invention are suitable for several applications, for example for treating denim and for strain removal.Type: ApplicationFiled: September 21, 2005Publication date: October 9, 2008Applicant: AB ENZYMES OYInventors: Marja Paloheimo, Terhi Puranen, Leena Valtakari, Kristiina Kruus, Jarno Kallio, Arja Mantyla, Richard Fagerstrom, Pentti Ojapalo, Jari Vehmaanpera
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Patent number: 7348172Abstract: The invention is related to a method and DNA constructs for obtaining in a filamentous fungus host a higher production level of a carbohydrate degrading (CD) enzyme, having in its original state a catalytic module (CAT) and a carbohydrate binding module (CBM) separated by a linker region. The DNA construct comprising a truncated actinomycetes, preferably Nonomuraea flexuosa (NJ) derived DNA sequence encoding a truncated form of the CD enzyme, for example Nf Xyn11A, Nf Xyn10A, and is introduced into a filamentous fungal host. Said CD enzyme contains the catalytically active region of CAT but lacks part or all of the CBM, or all of the CBM and part or all of the linker region and is expressed and secreted under the control of regulatory sequences comprising at least a signal sequence, but also promoters, terminators and DNA sequences encoding a secretable carrier protein or domains thereof, preferably originating from filamentous fungi are included.Type: GrantFiled: April 18, 2005Date of Patent: March 25, 2008Assignee: AB Enzymes OyInventors: Marja Paloheimo, Arja Mantyla, Sanna Leskinen, Richard Fagerstrom, Jarno Kallio, Terhi Puranen, Raija Lantto, Pirkko Suominen
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Patent number: 7323326Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.Type: GrantFiled: February 20, 2004Date of Patent: January 29, 2008Assignee: AB Enzymes OyInventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanpera, Heli Haakana, Arja Mantyla, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
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Patent number: 7273748Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.Type: GrantFiled: April 16, 2004Date of Patent: September 25, 2007Assignee: AB Enzymes OyInventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanpera, Heli Haakana, Arja Mantyla, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
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Publication number: 20060063246Abstract: The present invention relates to a novel laccase enzyme obtainable from the strains of genus Thielavia. The invention relates also to the nucleic acid sequence encoding the enzyme, a recombinant host into which the nucleic acid sequence has been introduced and a method for the production of the enzyme in a recombinant host. The enzyme of the invention is suitable for several applications, in particular for increasing the lightness of denim.Type: ApplicationFiled: September 21, 2005Publication date: March 23, 2006Applicant: AB Enzymes OYInventors: Marja Paloheimo, Leena Valtakari, Terhi Puranen, Kristiina Kruus, Jarno Kallio, Arja Mantyla, Richard Fagerstrom, Pentti Ojapalo, Jari Vehmaanpera
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Publication number: 20060014247Abstract: The invention is related to a method and DNA constructs for obtaining in a filamentous fungus host a higher production level of a carbohydrate degrading (CD) enzyme, having in its original state a catalytic module (CAT) and a carbohydrate binding module (CBM) separated by a linker region. The DNA construct comprising a truncated actinomycetes, preferably Nonomuraea flexuosa (NJ) derived DNA sequence encoding a truncated form of the CD enzyme, for example Nf Xyn11A, Nf Xyn10A, and is introduced into a filamentous fungal host. Said CD enzyme contains the catalytically active region of CAT but lacks part or all of the CBM, or all of the CBM and part or all of the linker region and is expressed and secreted under the control of regulatory sequences comprising at least a signal sequence, but also promoters, terminators and DNA sequences encoding a secretable carrier protein or domains thereof, preferably originating from filamentous fungi are included.Type: ApplicationFiled: April 18, 2005Publication date: January 19, 2006Inventors: Marja Paloheimo, Arja Mantyla, Sanna Leskinen, Richard Fagerstrom, Jarno Kallio, Terhi Puranen, Raija Lantto, Pirkko Suominen
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Publication number: 20040185498Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.Type: ApplicationFiled: April 16, 2004Publication date: September 23, 2004Inventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanpera, Heli Haakana, Arja Mantyla, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
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Publication number: 20040142444Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.Type: ApplicationFiled: February 20, 2004Publication date: July 22, 2004Inventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanpera, Heli Haakana, Arja Mantyla, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
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Patent number: 6723549Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.Type: GrantFiled: April 30, 1997Date of Patent: April 20, 2004Assignee: AB Enzymes OyInventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanperä, Heli Haakana, Arja Mäntylä, Raija Lanto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen
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Patent number: 6667170Abstract: The production of thermostable xylanses having bacterial origin is described. These compositions are useful for modifying plant biomass and for enzyme-aided bleaching of wood pulp.Type: GrantFiled: January 22, 1999Date of Patent: December 23, 2003Assignee: Röhm Enzyme Finland OyInventors: Arja Mäntylä, Marja Paloheimo, Raija Lantto, Richard Fagerström, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanperä
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Patent number: 6635464Abstract: DNA encoding novel xylanases, vectors containing such DNA, hosts transformed with such DNA, enzyme preparations, and the use of such preparations are described.Type: GrantFiled: May 7, 2001Date of Patent: October 21, 2003Assignee: Rohm Enzyme Finland OYInventors: Marja Paloheimo, Satu Hakola, Arja Mantyla, Jari Vehmaanpera, Raija Lantto, Tarja Lahtinen, Richard Fagerström, Pirkko Suominen
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Publication number: 20030148453Abstract: The present invention is related to an improved production of bacterial proteins in filamentous fungus, e.g. in Tfichodenna and Aspergillus. The improvement is achieved by constructing expression vectors, which comprise the bacterial protein encoding DNA sequences fused in frame with a DNA sequence encoding a filamentous fungus secretable protein or one or more functional domains of said protein. Filamentous fungus hosts transformed with such expression vectors secrete the desired proteins or enzymes, especially xylanases or cellulases originating from bacteria or more preferably from actinornycetes into the culture medium of the host. The desired proteins or enzymes can be used directly from the culture medium after separation of host cells or recovered and treated using down-stream processes, which are appropriate for the respective application. Xylanases or cellulases from actinomycetes produced using the above expression vectors are most suitable for treating plant derived materials e.g.Type: ApplicationFiled: August 13, 2002Publication date: August 7, 2003Applicant: Rohm Enzyme Finland OyInventors: Arja Mantyla, Marja Paloheimo, Raija Lantto, Richard Fagerstrom, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanpera
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Patent number: 6506593Abstract: The production of thermostable xylanses having bacterial origin is described. These compositions are useful for modifying plant biomass and for enzyme-aided bleaching of wood pulp.Type: GrantFiled: January 29, 2001Date of Patent: January 14, 2003Assignee: Rohm Enzyme Finland OYInventors: Arja Mäntylä, Marja Paloheimo, Raija Lantto, Richard Fagerström, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanperä
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Publication number: 20020168751Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described. The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.Type: ApplicationFiled: April 30, 1997Publication date: November 14, 2002Inventors: ARJA MIETTINEN-OINONEN, JOHN LONDESBOROUGH, JARI VEHMAANPERA, HELI HAAKANA, ARJA MANTYLA, RAIJA LANTTO, MINNA ELOVAINIO, VESA JOUTSJOKI, MARJA PALOHEIMO, PIRKKO SUOMINEN
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Publication number: 20010024815Abstract: The production of thermostable xylanses having bacterial origin is described. These compositions are useful for modifying plant biomass and for enzyme-aided bleaching of wood pulp.Type: ApplicationFiled: January 29, 2001Publication date: September 27, 2001Inventors: Arja Mantyla, Marja Paloheimo, Raija Lantto, Richard Fagerstrom, Tarja Lahtinen, Pirkko Suominen, Jari Vehmaanpera
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Patent number: 6228629Abstract: DNA encoding novel xylanases, vectors containing such DNA, hosts transformed with such DNA, enzyme preparations, and the use of such preparations are described.Type: GrantFiled: December 17, 1996Date of Patent: May 8, 2001Assignee: Röhn Enzyme Finland OYInventors: Marja Paloheimo, Satu Hakola, Arja Mäntylä, Jari Vehmaanperä, Raija Lantto, Tarja Lahtinen, Richard B. Fagerström, Pirkko Suominen
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Patent number: 6184019Abstract: Genes encoding novel cellulases, and a gene encoding a protein that facilitates the action of such novel cellulases, the novel cellulases and a protein that facilitates the action of such cellulases, and enzyme preparations containing such proteins are described The native hosts and the culture medium of said hosts containing said novel cellulases are also disclosed. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.Type: GrantFiled: June 10, 1999Date of Patent: February 6, 2001Assignee: Röhm Enzyme Finland OYInventors: Arja Miettinen-Oinonen, John Londesborough, Jari Vehmaanperä, Heli Haakana, Arja Mäntylä, Raija Lantto, Minna Elovainio, Vesa Joutsjoki, Marja Paloheimo, Pirkko Suominen