Patents by Inventor Arjo Lysander De Boer

Arjo Lysander De Boer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SECRETION YIELD OF A PROTEIN OF INTEREST BY IN VIVO PROTEOLYTIC PROCESSING OF A MULTIMERIC PRECURSOR
    Publication number: 20130273606
    Abstract: The invention relates to a nucleic acid molecule encoding a multimeric precursor which after transcription is specifically cleaved in vivo to form multiple copies of a protein of interest. The invention further relates to a cell comprising this nucleic acid molecule and a method for producing a protein of interest using this cell.
    Type: Application
    Filed: April 18, 2013
    Publication date: October 17, 2013
    Inventors: Anna Cornelia Hendrika VAN HAUTUM, Arjo Lysander DE BOER, Jan Bastiaan BOUWSTRA, Peter Franciscus Theresius Maria VAN ASTEN
  • Non-natural recombinant gelatins with enhanced functionality
    Patent number: 8349589
    Abstract: The invention concerns recombinant gelatin monomers and recombinant gelatins comprising or consisting of multimers of the monomers. The recombinant gelatins can be produced with enhanced stability.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: January 8, 2013
    Assignee: Fujifilm Manufacturing Europe B.V.
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • Recombinant XRGD-enriched gelatins having high stability
    Patent number: 8349588
    Abstract: The invention concerns recombinant gelatin monomers and recombinant gelatins comprising or consisting of multimers of the monomers. The recombinant gelatins are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anchor dependent cells and also in a variety of medical applications.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: January 8, 2013
    Assignee: Fujifilm Manufacturing Europe B.V.
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • RGD containing recombinant gelatin
    Patent number: 8198047
    Abstract: The invention concerns recombinant gelatins with unevenly distributed RGD motifs that are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anchor dependent cells and also in a variety of medical applications.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: June 12, 2012
    Assignee: Fujifilm Manufacturing Europe B.V.
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • Recombinant gelatins
    Patent number: 8173776
    Abstract: The invention concerns a recombinant CBE gelatin and recombinant gelatins having multimers of the CBE monomer sequence that are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anchor dependent cells and also in a variety of medical applications.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: May 8, 2012
    Assignee: Fujifilm Manufacturing Europe B.V.
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • RECOMBINANT GELATINS
    Publication number: 20120107372
    Abstract: The invention concerns a recombinant CBE gelatin and recombinant gelatins having multimers of the CBEmonomersequence that are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anchor dependent cells and also in a variety of medical applications.
    Type: Application
    Filed: December 2, 2011
    Publication date: May 3, 2012
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • Recombinant gelatins
    Patent number: 8158756
    Abstract: The invention concerns a recombinant CBE gelatin and recombinant gelatins having multimers of the CBE monomer sequence that are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anchor dependent cells and also in a variety of medical applications.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: April 17, 2012
    Assignee: Fujifilm Manufacturing Europe B.V.
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • Recombinant Protein Enriched in a Heparin Binding Site and/or in a Heparan Sulfate Binding Site
    Publication number: 20110256222
    Abstract: The invention relates to a recombinant protein enriched in a heparin binding site and/or a heparan sulfate binding site. Such recombinant protein is used as an in vivo controlled release system of a protein of interest.
    Type: Application
    Filed: April 7, 2009
    Publication date: October 20, 2011
    Inventors: Arjo Lysander De Boer, Jan Bastiaan Bouwstra
  • Secretion Yield of a Protein of Interest by in vivo Proteolytic Processing of a Multimeric Precursor
    Publication number: 20100273215
    Abstract: The invention relates to a nucleic acid molecule encoding a multimeric precursor which after transcription is specifically cleaved in vivo to form multiple copies of a protein of interest. The invention further relates to a cell comprising this nucleic acid molecule and a method for producing a protein of interest using this cell.
    Type: Application
    Filed: December 17, 2008
    Publication date: October 28, 2010
    Inventors: Anna Cornelia Hendrika Van Hautum, Arjo Lysander De Boer, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • High Yield Secretion of Multimeric Recombinant Protein
    Publication number: 20100256075
    Abstract: The present invention relates to high molecular weight gelatin-like proteins and methods for producing high yields thereof. Also, compositions comprising one or more of such proteins are provided.
    Type: Application
    Filed: September 9, 2008
    Publication date: October 7, 2010
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • Recombinant Gelatins
    Publication number: 20100119574
    Abstract: The invention concerns a recombinant CBE gelatin and recombinant gelatins having multimers of the CBE monomer sequence that are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anchor dependent cells and also in a variety of medical applications.
    Type: Application
    Filed: February 21, 2008
    Publication date: May 13, 2010
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • Non-Natural Recombinant Gelatins with Enhanced Functionality
    Publication number: 20100105618
    Abstract: The invention concerns recombinant gelatin monomers and recombinant gelatins comprising or consisting of multimers of the monomers. The recombinant gelatins can be produced with enhanced stability.
    Type: Application
    Filed: February 21, 2008
    Publication date: April 29, 2010
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • Recombinant XRGD-Enriched Gelatins Having High Stability
    Publication number: 20100075902
    Abstract: The invention concerns recombinant gelatin monomers and recombinant gelatins comprising or consisting of multimers of the monomers. The recombinant gelatins are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anchor dependent cells and also in a variety of medical applications.
    Type: Application
    Filed: February 21, 2008
    Publication date: March 25, 2010
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten
  • RGD Containing Recombinant Gelatin
    Publication number: 20100062531
    Abstract: The invention concerns recombinant gelatins with unevenly distributed RGD motifs that are of particular use in several applications involving cell attachment such as in cell culture work and applications involving cell cultures of anchor dependent cells and also in a variety of medical applications.
    Type: Application
    Filed: February 21, 2008
    Publication date: March 11, 2010
    Inventors: Arjo Lysander De Boer, Hendrik Van Urk, Jan Bastiaan Bouwstra, Peter Franciscus Theresius Maria Van Asten