Patents by Inventor Arjun Narayanan

Arjun Narayanan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KETOAMIDE IMMUNOPROTEASOME INHIBITORS
    Publication number: 20150274777
    Abstract: The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein X, R1, R1?, R2, R2?, R3, R4, R4? and R5 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are LMP7 inhibitors and may be useful in treating associated inflammatory diseases and disorders such as, for example, rheumatoid arthritis, lupus and irritable bowel disease.
    Type: Application
    Filed: September 30, 2013
    Publication date: October 1, 2015
    Inventors: Stephen M. Lynch, Arjun Narayanan, Sandra Steiner
  • MACROCYCLIC KETOAMIDE IMMUNOPROTEASOME INHIBITORS
    Publication number: 20150266920
    Abstract: The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein X, Y, Z, R1, R2, R3 and R3? are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are LMP7 inhibitors and may be useful in treating associated inflammatory diseases and disorders such as, for example, rheumatoid arthritis, lupus and irritable bowel disease.
    Type: Application
    Filed: October 9, 2013
    Publication date: September 24, 2015
    Inventors: Stephen M. Lynch, Arjun Narayanan