Patents by Inventor Arjun Ravikumar

Arjun Ravikumar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein engineering via error-prone orthogonal replication and yeast surface display
    Patent number: 11946055
    Abstract: Disclosed herein are methods, compositions, and kits for engineering proteins using error-prone orthogonal replication (epOrthoRep) and yeast surface display (YSD).
    Type: Grant
    Filed: December 9, 2021
    Date of Patent: April 2, 2024
    Assignees: The Regents of the University of California, President and Fellows of Harvard College
    Inventors: Chang C. Liu, Alon Wellner, Ziwei Zhong, Arjun Ravikumar, Andrew Kruse, Conor Thomas McMahon
  • A HIGHLY ERROR-PRONE ORTHOGONAL DNA REPLICATION SYSTEM FOR TARGETED CONTINUOUS EVOLUTION IN VIVO
    Publication number: 20230242902
    Abstract: The invention provides compositions comprising highly error-prone polymerases and methods of using the polymerases for rapid evolution of a nucleic acid sequence within host cells. The invention further provides a versatile synthetic biology platform for manipulating DNA replication inside a cell. The invention also provides a mutually orthogonal replication system for manipulating and tuning DNA replication of multiple nucleic acid molecules using the error-prone polymerases.
    Type: Application
    Filed: October 19, 2018
    Publication date: August 3, 2023
    Applicant: The Regents of the University of California
    Inventors: Chang C. Liu, Arjun Ravikumar, Garri A. Arzumanyan, Alex A. Javanpour
  • Protein Engineering via Error-Prone Orthogonal Replication and Yeast Surface Display
    Publication number: 20220195442
    Abstract: Disclosed herein are methods, compositions, and kits for engineering proteins using error-prone orthogonal replication (epOrthoRep) and yeast surface display (YSD).
    Type: Application
    Filed: December 9, 2021
    Publication date: June 23, 2022
    Inventors: Chang C. Liu, Alon Wellner, Ziwei Zhong, Arjun Ravikumar, Andrew Kruse, Conor Thomas McMahon