Abstract: A method for noninvasive analysis of subcutaneous tissue includes irradiating a surface of the tissue with short wave infrared (SWIR) radiation in a first spectral band that is strongly absorbed by water, and with SWIR radiation in a second spectral band such that an interaction of the radiation in both spectral bands with a component of the tissue other than water is substantially identical. An intensity of the radiation in each of the spectral bands that emerges from the tissue is measured. A relative absorption by the tissue of radiation in one of spectral bands relative to absorption by the tissue of radiation in the other of the spectral bands is calculated. A state of the tissue is determined in accordance with the calculated relative absorption.

Abstract: Systems, devices and methods for noninvasive analysis of tissue, by irradiating a surface of the tissue with infrared radiation such that an interaction of the radiation with a component of the tissue other than water in two spectral bands is substantially identical, measuring an intensity of the radiation that emerges from the tissue in each of the spectral bands, determining change in at least one of shape and intensity of signals received by the at least one radiation detector, calculating a relative absorption by the tissue of radiation in one of the first and second spectral bands relative to absorption by the tissue of radiation in the other of the first and second spectral bands, and determining concentration of a predetermined substance, in accordance with the calculated relative absorption and in accordance with determined change in the received signal.

Abstract: A method for noninvasive analysis of subcutaneous tissue includes irradiating a surface of the tissue with short wave infrared (SWIR) radiation in a first spectral band that is strongly absorbed by water, and with SWIR radiation in a second spectral band such that an interaction of the radiation in both spectral bands with a component of the tissue other than water is substantially identical. An intensity of the radiation in each of the spectral bands that emerges from the tissue is measured. A relative absorption by the tissue of radiation in one of spectral bands relative to absorption by the tissue of radiation in the other of the spectral bands is calculated. A state of the tissue is determined in accordance with the calculated relative absorption.

Abstract: A device for real-time tissue diagnosis of biological tissue having: a means for preparing a tissue sample before a measurement procedure; a means for positioning an ATR element and mirrors so as to perform a system calibration; a means for irradiating a sample with IR radiation using the ATR element and an opto-mechanical assembly; a means for recording the absorption spectrum of a sample being tested; a means for carrying out a Fourier transformation of the absorption spectrum obtained into a FT-IR spectrum; a means for calculating tissue characteristics on the basis of signal processing; a means for comparing the characteristics in a pre-selected wavenumber range with the reference spectra prepared and stored in a database.

Abstract: A method for noninvasive analysis of subcutaneous tissue includes irradiating a surface of the tissue with short wave infrared (SWIR) radiation in a first spectral band that is strongly absorbed by water, and with SWIR radiation in a second spectral band such that an interaction of the radiation in both spectral bands with a component of the tissue other than water is substantially identical. An intensity of the radiation in each of the spectral bands that emerges from the tissue is measured. A relative absorption by the tissue of radiation in one of spectral bands relative to absorption by the tissue of radiation in the other of the spectral bands is calculated. A state of the tissue is determined in accordance with the calculated relative absorption.

Abstract: Systems, devices and methods for noninvasive analysis of tissue, by irradiating a surface of the tissue with infrared radiation such that an interaction of the radiation with a component of the tissue other than water in two spectral bands is substantially identical, measuring an intensity of the radiation that emerges from the tissue in each of the spectral bands, determining change in at least one of shape and intensity of signals received by the at least one radiation detector, calculating a relative absorption by the tissue of radiation in one of the first and second spectral bands relative to absorption by the tissue of radiation in the other of the first and second spectral bands, and determining concentration of a predetermined substance, in accordance with the calculated relative absorption and in accordance with determined change in the received signal.

Abstract: A hybrid Attenuated Total Reflection fiber optic probe device having a radiation source; a detecting system; a core-only solid optical fiber probe tip having an input end and an output end; an input hollow fiber waveguide configured for association with the radiation source at a first end and interconnection with the input end of the core-only solid optical fiber probe tip at a second end; an output hollow fiber waveguide configured for interconnection with the output end of the core-only solid optical fiber probe tip at a first end and association with the detection system at a second end; an inwardly tapered solid fiber input radiation collector element configured at a tapered end for interconnection with the second end of the output hollow fiber waveguide so as to receive radiation from the radiation source; wherein an outside diameter of the core-only solid optical fiber probe tip and an inside diameter of each one of the input hollow fiber waveguide and the output hollow fiber waveguide is such that the

Abstract: A hybrid Attenuated Total Reflection fiber optic probe device having a radiation source; a detecting system; a core-only solid optical fiber probe tip having an input end and an output end; an input hollow fiber waveguide configured for association with the radiation source at a first end and interconnection with the input end of the core-only solid optical fiber probe tip at a second end; an output hollow fiber waveguide configured for interconnection with the output end of the core-only solid optical fiber probe tip at a first end and association with the detection system at a second end; an inwardly tapered solid fiber input radiation collector element configured at a tapered end for interconnection with the second end of the output hollow fiber waveguide so as to receive radiation from the radiation source; wherein an outside diameter of the core-only solid optical fiber probe tip and an inside diameter of each one of the input hollow fiber waveguide and the output hollow fiber waveguide is such that the

Abstract: A method for noninvasive analysis of subcutaneous tissue includes irradiating a surface of the tissue with short wave infrared (SWIR) radiation in a first spectral band that is strongly absorbed by water, and with SWIR radiation in a second spectral band such that an interaction of the radiation in both spectral bands with a component of the tissue other than water is substantially identical. An intensity of the radiation in each of the spectral bands that emerges from the tissue is measured. A relative absorption by the tissue of radiation in one of spectral bands relative to absorption by the tissue of radiation in the other of the spectral bands is calculated. A state of the tissue is determined in accordance with the calculated relative absorption.