Abstract: A method of stimulation of a body surface with application of a fluid matter pressure over a part of the body surface, a mechanical pressure on local points of the body surface, and a temperature change of the part of the body surface, the method comprises the steps of applying a negative fluid matter pressure over the whole part of the body surface; increasing the mechanical pressure on the local points distributed over the whole part of the body surface simultaneously with the applying the negative fluid matter pressure; cooling the part of the body surface simultaneously with the applying the negative fluid matter pressure and increasing the mechanical pressure on the local points; maintaining said negative fluid matter pressure, said increased mechanical pressure on the local points and said cooling over a preset period of time; then raising the pressure of the fluid matter over the whole part of the body surface; reducing the mechanical pressure on the local points of the part of the body surface simulta