Patents by Inventor Arlene Leon

Arlene Leon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adjustable sensitivity, genetic molecular interaction systems, including protein-protein interaction systems for detection and analysis
    Publication number: 20040180325
    Abstract: A method for detecting interactions between first and second interacting molecules a variable sensitivity. This variable sensitivity may be obtained by providing for the overexpression of either a bait hybrid protein containing a DNA binding domain (desensitization) or a prey hybrid protein containing the DNA activation domain for a reporter gene (enhanced sensitivity). The use of exogenous activators of one or the other according to the needs of a particular system is readily accomplished.
    Type: Application
    Filed: March 26, 2004
    Publication date: September 16, 2004
    Inventors: David N. Edwards, Arlene Leon, David F. Ranney
  • Adjustable sensitivity, genetic molecular interaction systems, including protein-protein interaction systems for detection and analysis
    Patent number: 6790607
    Abstract: A method for detecting interactions between first and second interacting molecules at variable sensitivity. This variable sensitivity may be obtained by providing for the overexpression of either a bait hybrid protein containing a DNA binding domain (desensitization) or a prey hybrid protein containing the DNA activation domain for a reporter gene (enhanced sensitivity). The use of exogenous activators of one or the other according to the needs of a particular system is readily accomplished.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: September 14, 2004
    Assignee: Hybrigen, Inc.
    Inventors: David N. Edwards, Arlene Leon, David F. Ranney