Patents by Inventor Armelle Bonfils

Armelle Bonfils has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6437157
    Abstract: A compound selected from the group consisting of a compound of the formula wherein R1 and R2 are individually selected from the group consisting of alkyl of 1 to 12 carbon atoms and aralkyl of 7 to 15 carbon atoms or taken together form a saturated heterocycle of 5 to 6 ring members optionally having a second ring heteroatom selected from the group consisting of sulfur, oxygen and nitrogen, R3 is an &agr;-alkyl of 1 to 8 carbon atoms, n is an integer from 2 to 15, R4 is alkyl of 1 to 12 carbon atoms, R5 is selected from the group consisting of hydrogen, alkyl of 1 to 12 carbon atoms and acyl of an organic carboxylic acid of up to 12 carbon atoms and the wavy lines indicate that the 17- and 20-asymmetrical centers are independent of the absolute R and S configurations and their non-toxic, pharmaceutically acceptable acid addition salts useful for controlling fertility in male warm-blooded animals.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: August 20, 2002
    Assignee: Hoechst Marion Roussel
    Inventors: Armelle Bonfils, Daniel Philibert
  • Patent number: 6083928
    Abstract: A method for facilitating the healing of skin comprising applying topically to skin a composition containing an amount of a lipopolysaccharide extracted from gram negative bacteria effective to facilitate skin healing.
    Type: Grant
    Filed: April 2, 1993
    Date of Patent: July 4, 2000
    Assignee: The Boots Company PLC
    Inventors: Armelle Bonfils, Pierre Smets, Rene Zalisz
  • Patent number: 5739124
    Abstract: A method of controlling male fertility in warm-blooded animals comprising vaginally administering to female warm-blooded animals an amount of a compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of alkyl of 1 to 8 carbon atoms and benzyl or taken together with the nitrogen form a saturated 5 to 6 ring heterocycle optionally containing a second nitrogen or oxygen in the ring, R.sub.3 is .alpha.- or .beta.-methyl, n is an integer from 2 to 10; R.sub.4 and R.sub.5 together are =0 or R.sub.4 is selected from the group consisting of hydrogen, --OH and acyloxy of an organic carboxylic acid of up to 12 carbon atoms and R.sub.5 is selected from hydrogen, --OH, acyloxy of an organic acid of up to 12 carbon atoms and alkyl, alkenyl and, alkynyl of up to 8 carbon atoms, R.sub.6 and R.sub.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: April 14, 1998
    Assignee: Roussel Uclaf
    Inventors: Armelle Bonfils, Daniel Philibert
  • Patent number: 5679668
    Abstract: The invention is a method of controlling fertility in male warm-blooded animals by administering a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of alkyl of 1 to 12 carbon atoms and aralkyl of 7 to 15 carbon atoms or taken together form a saturated heterocycle of 5 to 6 ring members optionally having a second ring heteroatom selected from the group consisting of sulfur, oxygen and nitrogen, R.sub.3 is an .alpha.-alkyl of 1 to 8 carbon atoms, n is an integer from 2 to 15, R.sub.4 is alkyl of 1 to 12 carbon atoms, R.sub.5 is selected from the group consisting of hydrogen, alkyl of 1 to 12 carbon atoms and acyl of an organic carboxylic acid of up to 12 carbon atoms and the wavy lines indicate that the 17- and 20- asymmetrical centers are independent of the absolute R and S configurations and their non-toxic, pharmaceutically acceptable acid addition salts.
    Type: Grant
    Filed: August 2, 1996
    Date of Patent: October 21, 1997
    Assignee: Roussel Uclaf
    Inventors: Armelle Bonfils, Daniel Philibert
  • Patent number: 5672595
    Abstract: A method of controlling male fertility in warm-blooded male animals comprising administering to male warm-blooded animals an amount of a compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are taken together with the nitrogen to form a saturated 5 to 6 ring heterocycle, optionally containing a second nitrogen or oxygen in the ring, R.sub.3 is .alpha.- or .beta.-methyl, n is an integer from 2 to 10, R.sub.4 and R.sub.5 together are .dbd.0 or R.sub.4 is selected from the group consisting of hydrogen, --OH and acyloxy of an organic carboxylic acid of up to 12 carbon atoms and R.sub.5 is selected from the group consisting of hydrogen, --OH, acyloxy of an organic carboxylic acid of up to 12 carbon atoms and alkyl, alkenyl and alkynyl of up to 8 carbon atoms, R.sub.6 and R.sub.7 together are .dbd.0 or are individually selected from the group consisting of hydrogen, --OH and acyloxy of an organic carboxylic acid of up to 12 carbon atoms or R.sub.5 and R.sub.
    Type: Grant
    Filed: December 11, 1995
    Date of Patent: September 30, 1997
    Assignee: Roussel UCLAF
    Inventors: Armelle Bonfils, Daniel Philibert
  • Patent number: 5635498
    Abstract: A method of controlling male fertility in warm-blooded animals comprising administering to male warm-blooded animals an amount of a compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of alkyl of 1 to 8 carbon atoms and benzyl, R.sub.3 is .alpha.- or .beta.- methyl, n is an integer from 2 to 10, either R.sub.4 and R.sub.5 together are .dbd.O and R.sub.6 and R.sub.7 are hydrogen, or R.sub.6 and R.sub.7 together are .dbd.O and R.sub.4 and R.sub.3 are hydrogen or R.sub.4 and R.sub.7 are .dbd.O and R.sub.6 and R.sub.5 are .dbd.O and their non-toxic, pharmaceutically acceptable acid addition salts in an amount sufficient to control male fertility.
    Type: Grant
    Filed: December 11, 1995
    Date of Patent: June 3, 1997
    Assignee: Roussel UCLAF
    Inventors: Armelle Bonfils, Daniel Philibert
  • Patent number: 5580864
    Abstract: A method of controlling male fertility in warm-blooded male animals comprising administering to male warm-blooded animals an amount of a compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of alkyl of 1 to 8 carbon atoms and benzyl, R.sub.3 is a .alpha.- or .beta.-methyl, n is an integer from 2 to 10, R.sub.4 is hydrogen, R.sub.5 is hydrogen, R.sub.6 and R.sub.7 are hydrogen, and their non-toxic, pharmaceutically acceptable acid addition salts in an amount sufficient to control male fertility.
    Type: Grant
    Filed: March 14, 1996
    Date of Patent: December 3, 1996
    Assignee: Roussel UCLAF
    Inventors: Armelle Bonfils, Daniel Philibert
  • Patent number: 5554604
    Abstract: A method of controlling male fertility in warm-blooded male animals comprising administering to male warm-blooded animals an amount of a compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of alkyl of 1 to 8 carbon atoms and benzyl or taken together with the nitrogen form a saturated 5 to 6 ring heterocycle optionally containing a second nitrogen or oxygen in the ring, R.sub.3 is .alpha.- or .beta.- methyl, n is an integer from 2 to 10, R.sub.4 and R.sub.5 together are .dbd.0 or R.sub.4 is selected from the group consisting of hydrogen, --OH and acyloxy of an organic carboxylic acid of up to 12 carbon atoms and R.sub.5 is selected from the group consisting of hydrogen, --OH, acyloxy of an organic carboxylic acid of up to 12 carbon atoms and alkyl, alkenyl and alkynyl of up to 8 carbon atoms, R.sub.6 and R.sub.7 together are .dbd.
    Type: Grant
    Filed: March 8, 1995
    Date of Patent: September 10, 1996
    Assignee: Roussel Uclaf
    Inventors: Armelle Bonfils, Daniel Philibert
  • Patent number: 5086040
    Abstract: A dermatological hair growth stimulating composition containing an effective amount of a glycoprotein extract of gram negative bacteria as the growth stimulant and a method of stimulating hair growth.
    Type: Grant
    Filed: October 16, 1990
    Date of Patent: February 4, 1992
    Assignee: Roussel Uclaf
    Inventors: Armelle Bonfils, Pierre Smets, Rene Zalisz