Patents by Inventor Armelle Novelli Rousseau
Armelle Novelli Rousseau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10704075Abstract: The invention concerns a method for determining the reaction of at least one bacterium of interest to its exposure to an antibiotic implementing a Raman spectroscopy analysis comprising the following steps: Having a biological sample that could contain said bacteria of interest, Preparing at least two fractions of said sample each comprising one or more living bacteria of interest, Capturing, in each fraction, at least one living bacterium of interest by using a binding partner, Exposing at least one of the fractions to at least one concentration of at least one given antibiotic, the other of the fractions being the control fraction, Submitting the bacterium/bacteria of interest contained in the fractions to an incident light and analyzing the resultant light obtained by Raman diffusion by the bacterium/bacteria of interest by Raman spectroscopy in order to obtain as many Raman spectra as bacteria, Treating said spectra in order to obtain a signature of the reaction of the or each bacterium/bacteria of intType: GrantFiled: November 25, 2016Date of Patent: July 7, 2020Assignees: BIOMÉRIEUX, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Armelle Novelli Rousseau, Isabelle Espagnon, Quentin Josso, Alice Douet, Frédéric Mallard, Olivier Gal
-
Publication number: 20180355399Abstract: The invention concerns a method for determining the reaction of at least one bacterium of interest to its exposure to an antibiotic implementing a Raman spectroscopy analysis comprising the following steps: Having a biological sample that could contain said bacteria of interest, Preparing at least two fractions of said sample each comprising one or more living bacteria of interest, Capturing, in each fraction, at least one living bacterium of interest by using a binding partner, Exposing at least one of the fractions to at least one concentration of at least one given antibiotic, the other of the fractions being the control fraction, Submitting the bacterium/bacteria of interest contained in the fractions to an incident light and analyzing the resultant light obtained by Raman diffusion by the bacterium/bacteria of interest by Raman spectroscopy in order to obtain as many Raman spectra as bacteria, Treating said spectra in order to obtain a signature of the reaction of the or each bacterium/bacteria of intType: ApplicationFiled: November 25, 2016Publication date: December 13, 2018Inventors: Armelle NOVELLI ROUSSEAU, Isabelle ESPAGNON, Quentin JOSSO, Alice DOUET, Frédéric MALLARD, Olivier GAL
-
Patent number: 9359631Abstract: A method for observing a sample is provided. The method includes the steps of: a) providing a volume (G, V) of a substantially transparent medium having a first refractive index (nint) and having a first surface (S1) that is convex, rounded, or faceted, and a second substantially planar surface (S2), the first surface separating the volume from a surrounding medium (MA) having a second refractive index (nest) that is lower than the first index, the sample to be observed being contained inside the volume or being deposited on the first surface; b) observing the sample through the second substantially planar surface; and c) determining the presence of a substance or an object in the sample by detection during step b), a ring of light that correlates with the volume.Type: GrantFiled: February 16, 2012Date of Patent: June 7, 2016Assignees: Commissariat a L'Energie Atomique et aux Energies Alternatives, BiomerieuxInventors: Mathieu Dupoy, Pierre Joly, Frédéric Mallard, Pierre Marcoux, Raphaël Mathey, Armelle Novelli-Rousseau
-
Publication number: 20130344532Abstract: A method for observing a sample is provided. The method includes the steps of: a) providing a volume (G, V) of a substantially transparent medium having a first refractive index (nint) and having a first surface (S1) that is convex, rounded, or faceted, and a second substantially planar surface (S2), the first surface separating the volume from a surrounding medium (MA) having a second refractive index (next) that is lower than the first index, the sample to be observed being contained inside the volume or being deposited on the first surface; b) observing the sample through the second substantially planar surface; and c) determining the presence of a substance or an object in the sample by detection during step b), a ring of light that correlates with the volume.Type: ApplicationFiled: February 16, 2012Publication date: December 26, 2013Applicant: BIOMERIEUXInventors: Mathieu Dupoy, Pierre Joly, Frédéric Mallard, Pierre Marcoux, Raphaël Mathey, Armelle Novelli-Rousseau
-
Patent number: 8129113Abstract: Analysis chip of at least one analyte, said chip comprising at least one analysis spot for recognition and immobilization specific to the analyte; and a reference range (G) comprising several reference spots each arranged on said chip in a defined manner and independently of one another, each reference spot of this range comprising, immobilized on its surface and in a defined proportion P that is different and known for each spot relative to the other reference spots of said range: a probe reference molecule (PRM) permitting recognition and hybridization specifically to a defined target reference molecule (TRM), and/or an inert oligonucleotide molecule (IM) incapable of recognition and hybridization with said PRM, these molecules both being unable to immobilize said analyte or analytes. The method of the invention comprises the use of said chip with its reference range for analysis of said, at least one, analyte.Type: GrantFiled: December 23, 2004Date of Patent: March 6, 2012Assignee: Commissariat a l'Energie AtomiqueInventors: Frédéric Ginot, Armelle Novelli-Rousseau, Frédéric Mallard, Florence Ricoul
-
Publication number: 20080254448Abstract: Analysis chip of at least one analyte, said chip comprising at least one analysis spot for recognition and immobilization specific to the analyte; and a reference range (G) comprising several reference spots each arranged on said chip in a defined manner and independently of one another, each reference spot of this range comprising, immobilized on its surface and in a defined proportion P that is different and known for each spot relative to the other reference spots of said range: a probe reference molecule (PRM) permitting recognition and hybridization specifically to a defined target reference molecule (TRM), and/or an inert oligonucleotide molecule (IM) incapable of recognition and hybridization with said PRM, these molecules both being unable to immobilize said analyte or analytes. The method of the invention comprises the use of said chip with its reference range for analysis of said, at least one, analyte.Type: ApplicationFiled: December 23, 2004Publication date: October 16, 2008Inventors: Frédéric Ginot, Armelle Novelli-Rousseau, Frederic Mallard, Florence Ricoul
-
Patent number: 6884582Abstract: The present invention relates to a method for detection of a molecular recognition reaction without labelling and a device for using this method. This invention concerns the general field of detection and analysis of molecular recognition between a first and a second molecule, for example a biological molecule. The method of the present invention consists of the detection of the molecular recognition by a photothermal method.Type: GrantFiled: September 29, 2000Date of Patent: April 26, 2005Assignees: Commissariat a l'Energie Atomique, Biomerieux SA.Inventors: Patrick Chaton, Ludovic Poupinet, Frédéric Ginot, Armelle Novelli Rousseau
-
Publication number: 20050033019Abstract: The invention concerns a nucleotide sequence coding for a modified protein of interest, said protein of interest having, after purification and immobilization, at least the same biological activity as the native protein of interest and being directly usable, said sequence comprising at least a gene coding for said protein of interest, a nucleotide fragment, called polyK, coding for a succession of at least six lysine residues, and a nucleotide fragment, called polyH, coding for a succession of at least six histidine residues; a vector comprising such a sequence; and a method for obtaining a purifiable and immobilized modified protein of interest.Type: ApplicationFiled: November 21, 2002Publication date: February 10, 2005Inventors: Francois Mallet, Valerie Cheynet, Guy Oriol, Laure Allard, Armelle Novelli-Rousseau
-
Patent number: 6632615Abstract: The invention concerns a method for isolating a target biological material contained in a sample, which consists in providing a capture phase comprising an organic molecule having at least a reactive function and at least a protein material capable of recognizing or binding, specifically and directly or indirectly, with the target biological material, said protein material having a specific covalent binding site with the organic molecule reactive function, consisting of at least a tag comprising at least six contiguous lysine, or lysine derivative residues, the method consists in contacting said target biological material with at least the capture phase; and detecting the target biological material fixed on the capture phase: The invention also concerns the capture and detection phases, and a reagent containing them.Type: GrantFiled: April 21, 1999Date of Patent: October 14, 2003Assignee: Bio MerieuxInventors: Francois Mallet, Thierry DeLair, Catherine Ladaviere, Armelle Novelli-Rousseau, Marie-Helene Charles
-
Publication number: 20020192840Abstract: The invention concerns a method for isolating a target biological material contained in a sample, which consists in providing a capture phase comprising an organic molecule having at least a reactive function and at least a protein material capable of recognizing or binding, specifically and directly or indirectly, with the target biological material, said protein material having a specific covalent binding site with the organic molecule reactive function, consisting of at least a tag comprising at least six contiguous lysine, or lysine derivative residues, the method consists in contacting said target biological material with at least the capture phase; and detecting the target biological material fixed on the capture phase: The invention also concerns the capture and detection phases, and a reagent containing them.Type: ApplicationFiled: April 21, 1999Publication date: December 19, 2002Inventors: FRANCOIS MALLET, THIERRY DELAIR, CATHERINE LADAVIERE, ARMELLE NOVELLI-ROUSSEAU, MARIE-HELENE CHARLES
-
Publication number: 20020160526Abstract: The invention concerns a method for isolating a target biological material contained in a sample, consisting in the following steps: providing a capture phase, in microparticulate or linear form, consisting of at least a first particulate or linear polymer, with apparent hydrophile character and first complexing groups, the latter being bound by co-ordination to a first transition metal, which is itself bound to a frist biological entity capable of specifically recongnising the target biological material; contacting said target biological material with at least the capture phase; and detecting the capture phase-target biological material complex, optionally with a detection phase, in microparticulate or linear form, and consisting of at least a second particulate or linear polymer, with apparent hydrophile character and second complexing groups, the latter being bound by co-ordination to a second transition metal, which is itself bound to a second biological entity capable of specifically recognizing the targType: ApplicationFiled: January 7, 2000Publication date: October 31, 2002Inventors: ABDELHAMID ELAISSARI, DAVID DURACHER, CHRISTIAN PICHOT, FRANCOIS MALLET, ARMELLE NOVELLI-ROUSSEAU