Patents by Inventor Armin Rossler

Armin Rossler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof
    Patent number: 7132544
    Abstract: The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification below. The present invention further relates to a process for preparing the compound of formula (II) and novel crystalline structures of the compound of formula (II).
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: November 7, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Hua Zhong, Silke Dubberke, Stefan Müller, Armin Rossler, Thomas W. Schultz, Daniel J. Korey, Thomas Otten, Donald G. Walker, Ahmed Abdel-Magid
  • Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof
    Patent number: 7067671
    Abstract: The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification below. The present invention further relates to a process for preparing the compound of formula (II) and novel crystalline structures of the compound of formula (II).
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: June 27, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Hua Zhong, Silke Dubberke, Stefan Müller, Armin Rossler, Thomas W. Schultz, Daniel J. Korey, Thomas Otten, Donald G. Walker, Ahmed Abdel-Magid
  • Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof
    Publication number: 20060030712
    Abstract: The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification below. The present invention further relates to a process for preparing the compound of formula (II) and novel crystalline structures of the compound of formula (II).
    Type: Application
    Filed: October 4, 2005
    Publication date: February 9, 2006
    Inventors: Hua Zhong, Silke Dubberke, Stefan Muller, Armin Rossler, Thomas Schultz, Daniel Korey, Thomas Otten, Donald Walker, Ahmed Abdel-Magid
  • Process for the preparation of imidazopyridines
    Patent number: 6841679
    Abstract: A compound of the general formula (1), in which: Y denotes hydrogen, a halogen or a C1-4 alkyl group; X1 and X2 denote, independently of each other, hydrogen, a halogen, a C1-4 alkoxy, C1-6 alkyl, CF3, CH3S CH3SO2 or NO2 group; and R1 and R2 denote independently of each other, hydrogen or a C1-5 alkyl group, with the proviso that R1 and R2 do not both denote hydrogen, or a salt thereof, and is prepared by a multi-step process, the last step of which comprises reducing a compound of the general formula (6), in which Y, X1, X2, R1 and R2 are as defined above with an appropriate reducing agent, such as Zn, and, if desired, converting the compound of formula (1) thus obtained, into a salt. The products of this process are known to have useful pharmacological properties, e.g. as anxiolytics.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: January 11, 2005
    Assignee: Cilag AG
    Inventors: Heidedore Hisabeth Rey-Papina, Armin Rossler, Giusep Derungs, Jae Kyoung Pak, Max Rey
  • Process for the preparation of imidazopyridines
    Publication number: 20040072861
    Abstract: A compound of general formula (1), in which: Y denotes hydrogen, a halogen or a C1-4 alkyl group X1 and X2 denote, independently of each other, hydrogen, a halogen or a C1-4 alkoxy, C1-6 alkyl, CF3, CH3S CH3SO2 or NO2 group and R1 and R2 denote independently of each other, hydrogen or a C1-5 alkyl group, with the proviso that R1 and R2 do not both denote hydrogen, or a salt thereof is prepared by a multi-step process, the last step of which comprises reducing a compound of the general formula (6), in which Y, X1, X2, R1 and R2 are as defined above with an appropriate reducing agent, such as Zn, and, if desired, converting the compound of formula (1) thus obtained, into a salt. The products of this process are known to have useful pharmacological properties, e.g. as anxiolytics.
    Type: Application
    Filed: November 24, 2003
    Publication date: April 15, 2004
    Inventors: Max Rey, H. J. Rey-Papina, Armin Rossler, Giusep Derungs, Jae Kyoung Pak
  • Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof
    Publication number: 20030045723
    Abstract: The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) 1
    Type: Application
    Filed: February 22, 2002
    Publication date: March 6, 2003
    Inventors: Hua Zhong, Silke Dubberke, Stefan Muller, Armin Rossler, Thomas W. Schultz, Daniel J. Korey, Thomas Otten, Donald G. Walker, Ahmed Abdel-Magid
  • Process for preparing [S-(R*,S*)]-&bgr;-[[[1-[1-oxo-3(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridinepropanoic acid and derivatives
    Patent number: 6515130
    Abstract: A process for preparing a compound of formula I wherein R1 and R2 are independently selected from the group consisting of hydrogen, lower alkyl and halogen
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: February 4, 2003
    Inventors: Judith H. Cohen, Michael Justus, Cynthia A. Maryanoff, Armin Rössler, Fridtjof Schröder, Kirk L. Sorgi, Frank J. Villani, Jr., Christian Weh
  • Process for preparing [S- (R*, S*) ] -beta- [ [ [1- [1-oxo-3- (4-piperidinyl) propyl] -3-piperidinyl] carbonyl]amino] -3-pyridinepropanoic acid and derivatives
    Publication number: 20020137937
    Abstract: A process for preparing a compound of formula I 1
    Type: Application
    Filed: February 22, 2002
    Publication date: September 26, 2002
    Inventors: Judith H. Cohen, Michael Justus, Cynthia A. Maryanoff, Armin Rossler, Fridtjof Harmen Schroder, Kirk L. Sorgi, Frank J. Villani, Christian Weh
  • Process for forming an amide bond
    Publication number: 20010037011
    Abstract: A process for forming an amide bond comprising reacting a carboxylic acid with an amine carboxylate salt, in the presence of an inorganic base.
    Type: Application
    Filed: March 8, 2001
    Publication date: November 1, 2001
    Inventor: Armin Rossler