Abstract: A mounting device for mounting a sample separation unit configured for separating, preferably chromatographically separating, compounds in a fluidic sample includes a first fluid connector configured for being mechanically and fluidically coupled with a first fluid interface of the sample separation unit, a second fluid connector configured for being mechanically and fluidically coupled with a second fluid interface of the sample separation unit, and a swivel mechanism configured for swivelling the first fluid connector between a mounting orientation for mounting the first fluid interface of the sample separation unit at the first fluid connector and an alignment orientation for aligning the second fluid interface of the mounted sample separation unit with the second fluid connector for subsequently coupling the second fluid interface with the second fluid connector.

Abstract: A fluidic coupling is positioned between a first fluidic structure and a second fluidic structure. The first fluidic structure has a first channel configured for conducting fluid and opening at a first opening at a first surface of the first fluidic structure. The second fluidic structure has a second channel configured for conducting fluid and opening at a second opening at a second surface of the second fluidic structure. The fluidic coupling includes a sealing element and an elastic structure. The elastic structure may be elastically deformed by the sealing element, thus allowing a fluidic communication between the first channel and the second channel.

Abstract: A valve may be utilized in a high-performance chromatography system for separating components of a sample liquid introduced into a mobile phase. The valve has a first valve element and a second valve element. By a movement of one valve element relative to the other, a first effective surface of the first valve element is brought into connection with a second effective surface of the second valve element, and a flow path may be produced or suppressed. The second valve element has an elastic region to compensate for an axial angle between the first valve element and the second valve element, such that the first effective surface and the second effective surface may be oriented parallel to each other. This may favorably influence a fluidic leak tightness and/or longevity of the valve.

Abstract: A microfluidic component for a sample separation device includes a layer body with multiple metal layer structures that are connected with each other, and an element made of a material different from the metal layer structures, which includes at least one microfluidic structure and is bonded with the layer body.

Abstract: A valve, such as for a high performance chromatography system for separating components of a sample liquid introduced into a mobile phase, includes a rotor and a stator, wherein a flow path can be established or inhibited by a rotational movement of the rotor relative to the stator. The valve also includes a compensation element, which is axially arranged together with the rotor and the stator and, in an operating state of the valve, causes an axial pressing of the rotor relative to the stator. The compensation element includes at least one spherical surface to compensate for an axial misalignment between the rotor and the stator.

Abstract: A mounting device for mounting a sample separation unit configured for separating, preferably chromatographically separating, compounds in a fluidic sample includes a first fluid connector configured for being mechanically and fluidically coupled with a first fluid interface of the sample separation unit, a second fluid connector configured for being mechanically and fluidically coupled with a second fluid interface of the sample separation unit, and a swivel mechanism configured for swivelling the first fluid connector between a mounting orientation for mounting the first fluid interface of the sample separation unit at the first fluid connector and an alignment orientation for aligning the second fluid interface of the mounted sample separation unit with the second fluid connector for subsequently coupling the second fluid interface with the second fluid connector.

Abstract: A fluidic valve for a sample separation apparatus for separating a fluid, wherein the fluidic valve comprises a stack of connected layer structures, a first conduit within the stack, a second conduit within the stack, a movable body within the stack, and an actuator configured for actuating the movable body to selectively bring the movable body into a flow enabling configuration in which flow of fluid between the first conduit and the second conduit is enabled, or into a flow disabling configuration in which flow of fluid between the first conduit and the second conduit is disabled.

Abstract: A pre-heater assembly for pre-heating a fluid, in particular in a fluid separation apparatus, wherein the pre-heater assembly comprises a capillary having a lumen and being configured for conducting the fluid, and a thermal coupling body contacting at least part of the capillary, having a value of thermal conductivity in a range between 8 W/(m K) and 100 W/(m K) and being arrangable so that heat generated by a heat source is supplied to the capillary via at least part of the thermal coupling body.

Abstract: An arrangement for mounting components in a heating chamber for heating a fluid of a fluid separation apparatus, wherein the arrangement comprises a mounting board having at least one mounting recess each configured for accommodating at least one component, and the at least one component each configured to be mountable in and/or on the at least one mounting recess.

Abstract: A pre-heater assembly for pre-heating a fluid, in particular in a fluid separation apparatus, wherein the pre-heater assembly comprises a capillary having a lumen and being configured for conducting the fluid, and a thermal coupling body contacting at least part of the capillary, having a value of thermal conductivity in a range between 8 W/(m K) and 100 W/(m K) and being arrangable so that heat generated by a heat source is supplied to the capillary via at least part of the thermal coupling body.

Abstract: A pre-heater assembly (90) for pre-heating a fluid, in particular in a fluid separation apparatus (10), wherein the pre-heater assembly (90) comprises a capillary (200) having a lumen and being configured for conducting the fluid, and a thermal coupling body (202) contacting at least part of the capillary (200), having a value of the thermal conductivity in a range between 8 W/(m K) and 100 W/(m K) and being arrangable so that heat generated by a heat source (80) is supplied to the capillary (200) via at least part of the thermal coupling body (202).

Abstract: A fluidic valve for a sample separation apparatus for separating a fluid, wherein the fluidic valve comprises a stack of connected layer structures, a first conduit within the stack, a second conduit within the stack, a movable body within the stack, and an actuator configured for actuating the movable body to selectively bring the movable body into a flow enabling configuration in which flow of fluid between the first conduit and the second conduit is enabled, or into a flow disabling configuration in which flow of fluid between the first conduit and the second conduit is disabled.

Abstract: Disclosed is a pressure determining unit configured for determining a pressure of a fluid. The pressure determining unit comprises a body structure and a deformation detector. The body structure has a fluidic path configured for conducting the fluid, wherein the body structure has a first surface in a first dimension and in a second dimension, and a thickness in a third dimension. The deformation detector is configured for responding to an elongation into the second dimension of the first surface of the body structure by generating a signal indicative of a value of the pressure of the fluid in the body structure. The fluidic path of the body structure comprises one or more first channel segments, each first channel segment having a height into the third dimension being at least twice of its width into the second dimension.

Abstract: An adjustable aperture device for an electromagnetic radiation detecting apparatus includes a position adjustment body configured for adjusting a position of a selected aperture hole of multiple selectable aperture holes, where electromagnetic radiation propagates through the selected aperture hole. The adjustable aperture device further includes a guide unit configured for guiding the position adjustment body along a predefined guide direction, and an aperture body defining the aperture holes and including multiple engagement sections, where the adjustment body is engagable in a selectable one of the engagement sections to thereby select the selected aperture hole. The adjustable aperture device further includes a pre-loading element configured for pre-loading the position adjustment body towards the aperture body, and a drive unit configured for driving the aperture body to move so that the position adjustment body is engaged in a respective one of the plurality of engagement sections.

Abstract: A base station for separating a fluidic sample by liquid chromatography in cooperation with a liquid chromatography analysis unit configured for executing a predefined liquid chromatography analysis task, wherein the base station comprises an analysis unit coupling section configured for removably coupling the liquid chromatography analysis unit to the base station, and an analysis task identification unit configured for identifying the predefined liquid chromatography analysis task of the liquid chromatography analysis unit coupled to the analysis unit coupling section, so that the fluidic sample is separable by executing the identified predefined liquid chromatography analysis task in cooperation between the base station and the liquid chromatography analysis unit.

Abstract: A liquid chromatography analysis unit configured for executing a predefined liquid chromatography analysis task, wherein the liquid chromatography analysis unit comprises a sample insertion compartment configured for inserting a fluidic sample to be separated, wherein the fluidic sample is to be separated when executing the liquid chromatography analysis task, a solvent accommodation section accommodating a predefined volume of at least one predefined solvent required for executing the liquid chromatography analysis task, and a sample separation unit configured for separating the fluidic sample inserted into the sample insertion compartment upon applying a solvent and sample drive force for driving the solvent and the fluidic sample through the sample separation unit.

Abstract: Disclosed is a pressure determining unit configured for determining a pressure of a fluid. The pressure determining unit comprises a body structure and a deformation detector. The body structure has a fluidic path configured for conducting the fluid, wherein the body structure has a first surface in a first dimension and in a second dimension, and a thickness in a third dimension. The deformation detector is configured for responding to an elongation into the second dimension of the first surface of the body structure by generating a signal indicative of a value of the pressure of the fluid in the body structure. The fluidic path of the body structure comprises one or more first channel segments, each first channel segment having a height into the third dimension being at least twice of its width into the second dimension.

Abstract: An arrangement for mounting components in a heating chamber for heating a fluid of a fluid separation apparatus, wherein the arrangement comprises a mounting board having at least one mounting recess each configured for accommodating at least one component, and the at least one component each configured to be mountable in and/or on the at least one mounting recess.

Abstract: A pre-heater assembly (90) for pre-heating a fluid, in particular in a fluid separation apparatus (10), wherein the pre-heater assembly (90) comprises a capillary (200) having a lumen and being configured for conducting the fluid, and a thermal coupling body (202) contacting at least part of the capillary (200), having a value of the thermal conductivity in a range between 8 W/(m K) and 100 W/(m K) and being arrangable so that heat generated by a heat source (80) is supplied to the capillary (200) via at least part of the thermal coupling body (202).

Abstract: A valve having at least one first valve chamber (1) which has an inlet opening (2) for the supply of a medium and a valve opening (3) which can be closed off by means of a valve body (4), which valve body (4) is acted on by a spring force (F K) which acts in the closing direction and which is generated by a force store (9) which has a spring constant and which valve body (4) can be adjusted counter to the spring force (F K) by means of an actuating element (5) to which an actuating force (F S) which acts counter to the spring force (F K) can be applied at an action point (10), is characterized in that means (7, 8) are provided, by way of which the spring constant which acts at the action point (10) of the actuating force (F S) can be set.