Abstract: The invention is notably directed to an oscillating reaction device. The device basically includes a structured layer of a matrix material and structural elements. Cavities are defined (for example, as blind holes) in the structured layer to allow the cavities to be filled with an oscillating reaction liquid containing nonpolar molecules of a given molecular species, with a view to triggering an oscillating reaction. Centers of the cavities are arranged according to a 2D lattice, whereby pairs of nearest-neighbor cavities of said cavities are, each, separated by a portion of the matrix material. This portion of material is selectively permeable to said nonpolar molecules. This, in operation, yields an inhibitory chemical coupling of the filled cavities of said pairs of nearest-neighbor cavities, where the inhibitory chemical coupling is mediated by said nonpolar molecules. Also, the structural elements connect the cavities to yield a positive chemical coupling of the filled cavities.

Abstract: The present invention relates to a pharmaceutical combination comprising an FGFR4 inhibitor and a bile acid sequestrant, to the use of the pharmaceutical combination in the treatment of cancer, to the use of a bile acid sequestrant to reduce or mitigate side-effects associated with FGFR4 inhibition therapy.

Abstract: The present invention relates to a pharmaceutical combination comprising an FGFR4 inhibitor and a bile acid sequestrant, to the use of the pharmaceutical combination in the treatment of cancer, to the use of a bile acid sequestrant to reduce or mitigate side-effects associated with FGFR4 inhibition therapy.

Abstract: A corrugated packing grid with consecutively arranged wave crests and wave troughs for a structured packing, which is assembled from several packing grids, for gas-liquid contacting apparatuses, and a packing assembled from the packing grids. The packing grid and the packing have a large mass transfer area and a low pressure drop at the same time and offer a high mechanical strength. This can be achieved in that elements lie in the region of the wave troughs of the packing grid, the elements extending into the wave troughs.

Abstract: The invention relates to a corrugated packing grid with consecutively arranged wave crests and wave troughs for a structured packing, which is assembled from several packing grids, for gas-liquid contacting apparatuses, and to a packing assembled from said packing grids. The aim of the invention is to provide a packing grid and a packing which have a large mass transfer area and a low pressure drop at the same time and which offer a high mechanical strength. According to the invention, this is achieved in that elements lie in the region of the wave troughs of the packing grid, said elements extending into the wave troughs.

Abstract: A method is disclosed for detecting the switch position of an isolating switch, or of a grounding switch, wherein a displaceable switching meter is applied to the contact part in the gap of a contact part in the closed switch position, and wherein the displaceable switch meter can be spaced from the contact part in the open switch position. In at least one embodiment, an optical signal is influenced by the switch meter for differentiating the two switch position with a closed switch position. If the optical signal is influenced, it is indicated that the isolating switch, or the grounding switch, is in the closed switch position. Otherwise it is indicated that the isolating switch, or the grounding switch, is in the open switch position.