Abstract: A computer system develops models and generates decision logic based on the developed models. The decision logic is distributed to end user devices, and the end user devices are able to implement the decision logic to detect events, determine event sequences, and correlate the determined event sequences to predicted outcomes.

Abstract: A weather intelligence system retrieves weather forecast data for a number of geographic regions. The weather intelligence system determines, using the weather forecast data for each of the geographic regions, a set of geographic regions predicted to experience a weather anomaly, or unusual weather condition, during a particular time interval. The weather intelligence system determines, through a machine-learning process, whether the weather forecast data indicates conditions that people would generally consider to be unusually hot or cold. The weather intelligence system can then programmatically enable a trigger to transmit a service-related offer associated with the weather anomaly to user devices located within one of the geographic regions where that weather anomaly is determined.

Abstract: Multilayer structures comprising a covalent organic framework (COF) film in contact with a polyaromatic carbon (PAC) film. The multilayer structures can be made by combining precursor compounds in the presence of a PAC film. The PAC film can be for example, a single layer graphene film. The multilayer structures can be used in a variety of applications such as solar cells, flexible displays, lighting devices, RFID tags, sensors, photoreceptors, batteries, capacitors, gas-storage devices, and gas-separation devices.

Abstract: A weather intelligence system retrieves weather forecast data for a number of geographic regions. The weather intelligence system determines, using the weather forecast data for each of the geographic regions, a set of geographic regions predicted to experience a weather anomaly, or unusual weather condition, during a particular time interval. The weather intelligence system determines, through a machine-learning process, whether the weather forecast data indicates conditions that people would generally consider to be unusually hot or cold. The weather intelligence system can then programmatically enable a trigger to transmit a service-related offer associated with the weather anomaly to user devices located within one of the geographic regions where that weather anomaly is determined.

Abstract: A computer system develops models and generates decision logic based on the developed models. The decision logic is distributed to end user devices, and the end user devices are able to implement the decision logic to detect events, determine event sequences, and correlate the determined event sequences to predicted outcomes.

Abstract: A network computing system, and method for implementing a network computing system, to analyze events accumulated over digital channels of an enterprise, for purpose of determining contextual and/or customized outputs that facilitate a desired objective of the enterprise.

Abstract: Multilayer structures comprising a covalent organic framework (COF) film in contact with a polyaromatic carbon (PAC) film. The multilayer structures can be made by combining precursor compounds in the presence of a PAC film. The PAC film can be for example, a single layer graphene film. The multilayer structures can be used in a variety of applications such as solar cells, flexible displays, lighting devices, RFID tags, sensors, photoreceptors, batteries, capacitors, gas-storage devices, and gas-separation devices.

Abstract: Subterranean treatment fluids comprising: an aqueous base fluid and a reaction product of a gelling agent comprising a copolymer or salt thereof comprising N-[tris(hydroxymethyl)methyl]acrylamide, 2-acrylamido-2-methylpropanesulfonic acid or a salt thereof, acrylamide; and a crosslinking agent. Such treatment fluids are particularly well-suited for high temperature applications. In particular, they are suited for subterranean temperatures up to about 400° F.

Abstract: Of the many methods and compositions provided by this invention, one method a method of treating a subterranean formation, comprising: providing a treatment fluid comprising: an aqueous base fluid and a reaction product of a gelling agent comprising a copolymer or salt thereof comprising N-[tris(hydroxymethyl)methyl]acrylamide, 2-acrylamido-2-methylpropanesulfonic acid or a salt thereof, and acrylamide; and a crosslinking agent; and introducing the treatment fluid into a subterranean formation.

Abstract: Subterranean treatment fluids comprising: an aqueous base fluid and a reaction product of a gelling agent comprising a copolymer or salt thereof comprising N-[tris(hydroxymethyl)methyl]acrylamide, 2-acrylamido-2-methylpropanesulfonic acid or a salt thereof, acrylamide; and a crosslinking agent. Such treatment fluids are particularly well-suited for high temperature applications. In particular, they are suited for subterranean temperatures up to about 400° F.

Abstract: Of the many methods and compositions provided by this invention, one method a method of treating a subterranean formation, comprising: providing a treatment fluid comprising: an aqueous base fluid and a reaction product of a gelling agent comprising a copolymer or salt thereof comprising N-[tris(hydroxymethyl)methyl]acrylamide, 2-acrylamido-2-methylpropanesulfonic acid or a salt thereof, and acrylamide; and a crosslinking agent; and introducing the treatment fluid into a subterranean formation.

Abstract: Provided is a class of radiolabeled androgen receptor targeting agents (ARTA), useful for prostate cancer imaging and in treating or preventing prostate cancer. The agents define a new subclass of radiolabeled compounds, which are selective androgen receptor modulators (SARM), which demonstrate antiandrogenic activity of a nonsteroidal ligand for the androgen receptor, and/or which bind irreversibly to the androgen receptor. The present invention further provides methods for a) imaging of cancer in a subject, b) imaging an androgen receptor-containing tissue in a subject, c) in-vivo imaging in a subject, d) treating a subject suffering from prostate cancer, e) delaying the progression of prostate cancer in a subject suffering from prostate cancer, f) preventing the recurrence of prostate cancer in a subject suffering from prostate cancer, and g) treating the recurrence of prostate cancer in a subject suffering from prostate cancer, which comprise using the radiolabeled compounds of the present invention.

Abstract: Provided is a class of radiolabeled androgen receptor targeting agents (ARTA), useful for prostate cancer imaging and in treating or preventing prostate cancer. The agents define a new-subclass of radiolabeled compounds, which are selective androgen receptor modulators (SARM), which demonstrate antiandrogenic activity of a nonsteroidal ligand for the androgen receptor, and/or which bind irreversibly to the androgen receptor. The present invention further provides methods for a) imaging of cancer in a subject, b) imaging an androgen receptor-containing tissue in a subject, c) in-vivo imaging in a subject, d) treating a subject suffering from prostate cancer, e) delaying the progression of prostate cancer in a subject suffering from prostate cancer, f) preventing the recurrence of prostate cancer in a subject suffering from prostate cancer, and g) treating the recurrence of prostate cancer in a subject suffering from prostate cancer, which comprise using the radiolabeled compounds of the present invention.

Abstract: The present invention relates to an androgen receptor alkylating compound, wherein the compound may include, inter alia, an active functional group, which permits the alkylation of the androgen receptor.

Abstract: The present invention relates to an antiandrogen compound and a method of treating prostate cancer in a patient utilizing the compound. The present invention also relates to a pharmaceutical composition which includes the compound.

Abstract: In one embodiment, this invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). The SARM compounds have unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor. In one embodiment, the SARM compounds bind irreversibly to the androgen receptor In another embodiment, the SARM compounds are androgen receptor antagonists, which bind irreversibly to the androgen receptor. In another embodiment, the SARM compounds are alkylating agents.

Abstract: The present invention relates to an androgen receptor alkylating compound, wherein the compound may include, inter alia, an active functional group, which permits the alkylation of the androgen receptor.

Abstract: In one embodiment, this invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). The SARM compounds have unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor. In one embodiment, the SARM compounds bind irreversibly to the androgen receptor. In another embodiment, the SARM compounds are androgen receptor antagonists which bind irreversibly to the androgen receptor. In another embodiment, the SARM compounds are alkylating agents.

Abstract: Provided is a class of radiolabeled androgen receptor targeting agents (ARTA), useful for prostate cancer imaging and in treating or preventing prostate cancer. The agents define a new-subclass of radiolabeled compounds, which are selective androgen receptor modulators (SARM), which demonstrate antiandrogenic activity of a nonsteroidal ligand for the androgen receptor, and/or which bind irreversibly to the androgen receptor. The present invention further provides methods for a) imaging of cancer in a subject, b) imaging an androgen receptor-containing tissue in a subject, c) in-vivo imaging in a subject, d) treating a subject suffering from prostate cancer, e) delaying the progression of prostate cancer in a subject suffering from prostate cancer, f) preventing the recurrence of prostate cancer in a subject suffering from prostate cancer, and g) treating the recurrence of prostate cancer in a subject suffering from prostate cancer, which comprise using the radiolabeled compounds of the present invention.

Abstract: The present invention relates to an antiandrogen compound and a method of treating prostate cancer in a patient utilizing the compound. The present invention also relates to a pharmaceutical composition which includes the compound.