Abstract: A cervical cell and fluid collector includes a substantially disc-shaped main body made of a high-density, non-absorbent, non-fibrous, biologically inert polyurethane foam. A porous membrane is mounted in a mainly concave collection recess in the main body. When the collector is in place adjacent to the cervix of a patient, cells and fluids adhere to the outer surface of the membrane. A layer of a cell-moistening material or agent is provided between the membrane and the inner surface of the recess; the cell-moistening material is preferably a pre-hydrated polymer gel that releases water during cell collection for moistening collected cells through the pores of the membrane when the cells are adhered to the outer surface of the membrane. The main body has an inward-slanting annular lip defining the recess and resiliently holding the membrane. The collector may remain in the vaginal cavity of the patient for up to at least 24 hours.