Patents by Inventor Arnaud Bonnefoy

Arnaud Bonnefoy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing cells for engraftment
    Patent number: 8828724
    Abstract: The present invention relates to an in vitro method for preparing progenitor cells having an increased adhesivity, wherein progenitor cells are contacted with an agonist of the CD47/IAP receptor thereby yielding progenitor cells presenting an increased adhesivity.
    Type: Grant
    Filed: August 14, 2008
    Date of Patent: September 9, 2014
    Assignee: Institut National de la Sante et de la Recherche Medicale (Inserm)
    Inventors: Olivier Blanc-Brude, Arnaud Bonnefoy
  • QUANTIFICATION OF CHANGES IN THE DEGREES OF ORDER OF CELLULAR AND VIRAL MEMBRANES AND APPLICATIONS TO DIAGNOSIS, TREATMENT AND DRUG SCREENING
    Publication number: 20100330604
    Abstract: A method for characterizing cell membrane order in a cell. The method includes: staining the cell with di-4-ANEPPDHQ to produce a stained cell; irradiating the stained cell with an excitation light, the excitation light being capable of inducing fluorescence in the di-4-ANEPPDHQ; measuring a fluorescence spectrum of the stained cell; and characterizing the cell membrane order by computing a spectral signature of the stained cell from the fluorescence spectrum, the spectral signature providing a character of the cell membrane order.
    Type: Application
    Filed: September 5, 2008
    Publication date: December 30, 2010
    Inventors: Benoit Labarthe, Ange Maguy, Arnaud Bonnefoy, Pierre Theroux
  • Polyhydroxy phenols and their use in binding p-selectin
    Patent number: 7273951
    Abstract: Polyhydroxy phenols, which are non-peptidic mimetics of galloyl peptides, and a process for the preparation of gallic acid derivatives using a gallic-acid providing moiety are provided as well as polyhydroxy phenol-containing pharmaceutical and nutraceutical compositions. The use of polyhydroxy phenols as a medicament and especially for the manufacture of a medicament for the prevention, treatment or diagnosis of a disease or a condition, wherein P-selectin is involved, is provided. The same compounds can also be used as targeting tools to P-selectin expressing cells or tissues in a composition, further comprising an active compound in a vehicle.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: September 25, 2007
    Assignee: Astellas Pharma Inc.
    Inventors: Erik Anna Leonardus Biessen, Chantal Catharina Maria Appeldoorn, Arnaud Bonnefoy, Theodorus Josephus Cornelis Van Berkel, Johan Kuiper, Marc Florimond Hoylaerts
  • Polyhydroxy phenols and their use in binding p-selectin
    Publication number: 20060276545
    Abstract: Polyhydroxy phenols, which are non-peptidic mimetics of galloyl peptides, and a process for the preparation of gallic acid derivatives using a gallic-acid providing moiety are provided as well as polyhydroxy phenol-containing pharmaceutical and nutraceutical compositions. The use of polyhydroxy phenols as a medicament and especially for the manufacture of a medicament for the prevention, treatment or diagnosis of a disease or a condition, wherein P-selectin is involved, is provided. The same compounds can also be used as targeting tools to P-selectin expressing cells or tissues in a composition, further comprising an active compound in a vehicle.
    Type: Application
    Filed: May 7, 2004
    Publication date: December 7, 2006
    Applicant: YAMANOUCHI PHARMACEUTICAL CO., LTD.
    Inventors: Erik Anna Biessen, Chantal Appeldoorn, Arnaud Bonnefoy, Theodorus Van Berkel, Johan Kuiper, Marc Hoylaerts