Patents by Inventor Arnaud Humair
Arnaud Humair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230055399Abstract: Embodiments herein relate to bioprosthetic heart valves. In an embodiment, a heart valve replacement system is included having a delivery catheter can include a heart valve accommodation region; and a heart valve disposed around the delivery catheter at the heart valve accommodation region of the delivery catheter, the heart valve can include a frame; and a plurality of valve leaflets coupled to the frame; wherein the valve leaflets include an animal tissue, the animal tissue can include from 15% to 50% by weight water; and from 20% to 70% by weight glycerol; a package defining an interior volume, wherein the delivery catheter and the heart valve are disposed within the package. Other embodiments are also included herein.Type: ApplicationFiled: September 20, 2022Publication date: February 23, 2023Inventor: Arnaud Humair
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Publication number: 20220096713Abstract: Embodiments herein relate to prosthetic heart valves constructed with animal tissue wherein the leaflets are unitary with the inner skirt. In an embodiment, an implantable heart valve assembly is included having a plurality of valve leaflets, an inner skirt, and a metal frame, wherein the plurality of valve leaflets and the inner skirt are formed of a continuous piece of animal tissue. In another embodiment, a method of making an implantable heart valve assembly is included, the method including placing a piece of pericardial tissue over a mold, cross-linking the pericardial tissue in place over the mold, removing the pericardial tissue from the mold, and attaching the pericardial tissue to a frame, wherein the pericardial tissue forms a seamless junction between a plurality of valve leaflets and an inner skirt. Other embodiments are also included herein.Type: ApplicationFiled: September 28, 2021Publication date: March 31, 2022Inventors: Arnaud Humair, Yutit Wanakoht
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Publication number: 20220061986Abstract: Embodiments herein relate to cardiac stent-valves for transcatheter delivery. A cardiac stent-valve for transcatheter delivery is compressible to a compressed state for delivery and expandable to an expanded state for implantation. The stent-valve can include a stent with an axial inflow end and an axial outflow end, a plurality of leaflets arranged within the stent, and a structured sealing skirt for reduction or prevention of paravalvular leakage. The structured sealing skirt comprises one or more sealing formations arranged on a radially outer surface of the structured sealing skirt. At least in the expanded state, at least one of the one or more sealing formations is shaped and arranged such that, at each axial level of the structured sealing skirt covered by the one or more sealing formations. Other embodiments are also included herein.Type: ApplicationFiled: September 3, 2021Publication date: March 3, 2022Inventors: Arnaud Humair, Jean-Luc Hefti, Stephane Delaloye
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Publication number: 20220061984Abstract: Embodiments herein include a cardiac stent-valve for transcatheter delivery being compressible to a compressed state for delivery, and expandable to an expanded state for implantation. The stent-valve including a stent with an axial inflow end and an axial outflow end, a plurality of leaflets arranged within the stent, and a sealing skirt for reduction or prevention of paravalvular leakage. In the expanded state, the sealing skirt includes a tubular inner wall and at least one pocket which is positioned on the tubular inner wall and comprises an outer wall which extends radially outward from the tubular inner wall. The pocket is configured to be distended radially outward in response to inflow of blood in the expanded state. In the expanded state, the outer wall of the pocket includes one or more pre-shaped bulges which extend radially outward from the outer wall of the pocket. Other embodiments are also included herein.Type: ApplicationFiled: September 3, 2021Publication date: March 3, 2022Inventors: Arnaud Humair, Jean-Luc Hefti, Stephane Delaloye
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Publication number: 20210346157Abstract: Embodiments include a valve leaflet for an implantable valve device comprising a leaflet body. The leaflet body comprising a free edge configured for coaptation with free edges of one or more other valve leaflets; and a root edge disposed opposite the free edge. The free edge defining an edge profile comprising a peak and valleys disposed on opposite sides of the peak. Other embodiments are also included herein.Type: ApplicationFiled: July 23, 2021Publication date: November 11, 2021Inventor: Arnaud Humair
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Publication number: 20210290379Abstract: Various embodiments of a seal for a stent-valve, and methods of production, are described. In some embodiments, the seal or a skirt comprises a fabric wall portion and a polymeric material fused to the fabric wall portion, the polymeric material having a melting temperature that is lower than that of the fabric wall portion. The fibres of the fabric may remain unmelted at the interface with the polymeric material, the polymeric material being attached to material to the fibres of the fabric wall portion by fusion. The polymeric material may provide a welded joint to another fabric wall portion and/or may reinforce the fabric and/or may occlude pores of the fabric.Type: ApplicationFiled: June 8, 2021Publication date: September 23, 2021Applicant: Boston Scientific LimitedInventors: Lionel Flaction, Stephane Delaloye, Youssef Biadillah, Arnaud Humair
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Patent number: 11071625Abstract: Embodiments include a valve leaflet for an implantable valve device comprising a leaflet body. The leaflet body comprising a free edge configured for coaptation with free edges of one or more other valve leaflets; and a root edge disposed opposite the free edge. The free edge defining an edge profile comprising a peak and valleys disposed on opposite sides of the peak. Other embodiments are also included herein.Type: GrantFiled: October 23, 2018Date of Patent: July 27, 2021Assignee: Boston Scientific LimitedInventor: Arnaud Humair
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Patent number: 11045312Abstract: Various embodiments of a seal for a stent-valve, and methods of production, are described. In some embodiments, the seal or a skirt comprises a fabric wall portion and a polymeric material fused to the fabric wall portion, the polymeric material having a melting temperature that is lower than that of the fabric wall portion. The fibres of the fabric may remain unmelted at the interface with the polymeric material, the polymeric material being attached to material to the fibres of the fabric wall portion by fusion. The polymeric material may provide a welded joint to another fabric wall portion and/or may reinforce the fabric and/or may occlude pores of the fabric.Type: GrantFiled: February 2, 2016Date of Patent: June 29, 2021Assignee: Boston Scientific LimitedInventors: Lionel Flaction, Stéphane Delaloye, Youssef Biadillah, Arnaud Humair
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Publication number: 20210154006Abstract: Embodiments herein relate to polymer coated prosthetic heart valves. In an embodiment, a method of manufacturing a heart valve is included, the method obtaining a frame, attaching a porous web to the frame, applying a coating over at least a portion of the porous web. In an embodiment a heart valve is included. The heart valve including a frame and a plurality of valve leaflets attached to the frame. Each valve leaflet can have a first polymer forming a porous support web and a second polymer forming a coating occluding pores in the porous support web. The valve leaflets can be attached to the frame with a connection structure that is at least partially covered by the coating. Other embodiments are also included herein.Type: ApplicationFiled: November 10, 2020Publication date: May 27, 2021Inventors: Arnaud Humair, Jean-Luc Hefti
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Publication number: 20210077253Abstract: Embodiments herein relate to bioprosthetic heart valves. In an embodiment, a heart valve replacement system is included having a delivery catheter can include a heart valve accommodation region; and a heart valve disposed around the delivery catheter at the heart valve accommodation region of the delivery catheter, the heart valve can include a frame; and a plurality of valve leaflets coupled to the frame; wherein the valve leaflets include an animal tissue, the animal tissue can include from 15% to 50% by weight water; and from 20% to 70% by weight glycerol; a package defining an interior volume, wherein the delivery catheter and the heart valve are disposed within the package. Other embodiments are also included herein.Type: ApplicationFiled: September 3, 2020Publication date: March 18, 2021Inventor: Arnaud Humair
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Publication number: 20190117391Abstract: Embodiments include a valve leaflet for an implantable valve device comprising a leaflet body. The leaflet body comprising a free edge configured for coaptation with free edges of one or more other valve leaflets; and a root edge disposed opposite the free edge. The free edge defining an edge profile comprising a peak and valleys disposed on opposite sides of the peak. Other embodiments are also included herein.Type: ApplicationFiled: October 23, 2018Publication date: April 25, 2019Inventor: Arnaud Humair