Abstract: A method of vascularising a cell aggregate on a microfluidic device, microfluidic cell culture devices comprising perfusable vascular networks and kits and assays using the microfluidic cell culture devices are described. The microfluidic devices comprise one or more capillary pressure barriers allowing for formation of an extracellular matrix gel within a confined area of the network, in which cells can be cultured for different uses.

Abstract: A method of vascularising a cell aggregate on a microfluidic device, microfluidic cell culture devices comprising perfusable vascular networks and kits and assays using the microfluidic cell culture devices are described. The microfluidic devices comprise one or more capillary pressure barriers allowing for formation of an extracellular matrix gel within a confined area of the network, in which cells can be cultured for different uses.

Abstract: A method is disclosed for automatic monitoring of a flight management assembly of an aircraft implementing air operations necessitating guaranteed navigation and guidance performance, wherein flight path data generated by first and second flight management systems respectively, are compared in order to check their consistency; first and second flight management systems transmit their flight path data to a third flight management system; the third flight management system receives a current position of the aircraft, calculates deviations between this current position and a flight path depending on the flight path data received from the first and second flight management systems, which it utilizes only if they are identical, and calculates, according to these deviations, guidance commands for slaving onto this flight path. Monitoring can compare deviations and guidance commands received from the first second and third flight management systems in order to be able to detect an inconsistency between them.

Abstract: A monitoring device includes one or more devices for implementing monitoring, in order to check whether two flight management systems are able to operate in dual mode during operations requiring navigation and guidance performance. For example, a change condition verification device may be included in a second or slave flight management system so that sequencing requests and resynchronization requests received from a first or master flight management system are verified for accuracy before implementation. The verification may include comparison of positional data used by the first and second flight management systems or a comparison of a resynchronized flight plan to information from a navigation data database.

Abstract: The monitoring device (1) comprises means (22) for implementing monitoring, in order to check whether two flight management systems (4, 5) are able to operate in dual mode.

Abstract: A separation and regrouping device for conductive elements such as optical fibers is disclosed. The device includes a housing and a plurality of conductive elements extending through an interior region thereof. The housing surrounds encapsulation discontinuities formed on the conductive elements. The housing can include a guide channel that channels the optical fibers through the interior region thereof and, optionally, rotates the fibers as they extend through the housing. The device can also include strain relief elements that contain the optical fibers and surround the encapsulation discontinuities, and potting chambers in which the optical fibers can be potted to the housing. Methods for organizing conductive elements are also disclosed that include providing a plurality of conductive elements arranged in first groups, separating the first groups into individual conductive elements, and rearranging the individual conductive elements into second groups.

Abstract: A separation and regrouping device for conductive elements such as optical fibers is disclosed. The device includes a housing and a plurality of conductive elements extending through an interior region thereof. The housing surrounds encapsulation discontinuities formed on the conductive elements. The housing can include a guide channel that channels the optical fibers through the interior region thereof and, optionally, rotates the fibers as they extend through the housing. The device can also include strain relief elements that contain the optical fibers and surround the encapsulation discontinuities, and potting chambers in which the optical fibers can be potted to the housing. Methods for organizing conductive elements are also disclosed that include providing a plurality of conductive elements arranged in first groups, separating the first groups into individual conductive elements, and rearranging the individual conductive elements into second groups.