Patents by Inventor Arnaud-Pierre Schaffner

Arnaud-Pierre Schaffner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them
    Patent number: 10654878
    Abstract: Compounds of formula (I) wherein: Ak1 represents an alkyl chain, X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)—, —N(R)—CH2— or —CH2—N(R)—CH2—, m and R are as defined in the description, R1 and R2 each represent H when X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)— or —N(R)—CH2—, or together form a bond when X represents —CH2—N(R)—CH2—, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yl, Cy and Ak3 are as defined in the description, R4 and R5, which may be identical or different, each represent H or F, their optical isomers, and addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating conditions requiring a TAFIa inhibitor.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: May 19, 2020
    Assignee: LES LABORATOIRES SERVIER
    Inventors: Philippe Gloanec, Arnaud-Pierre Schaffner, Patricia Sansilvestri-Morel, Alain Rupin, Philippe Mennecier, Marie-Odile Vallez
  • COMPOUNDS OF PHOSPHINANES AND AZAPHOSPHINANES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20190031693
    Abstract: Compounds of formula (I) wherein: Ak1 represents an alkyl chain, X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)—, N(R)—CH2— or —CH2—N(R)—CH2—, m and R are as defined in the description, R1 and R2 each represent H when X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)— or —N(R)—CH2—, or together form a bond when X represents —CH2—N(R)—CH2—, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yl, Cy and Ak3 are as defined in the description, R4 and R5, which may be identical or different, each represent H or F, their optical isomers, and addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating conditions requiring a TAFIa inhibitor.
    Type: Application
    Filed: October 4, 2018
    Publication date: January 31, 2019
    Inventors: Philippe GLOANEC, Arnaud-Pierre SCHAFFNER, Patricia SANSILVESTRI-MOREL, Alain RUPIN, Philippe MENNECIER, Marie-Odile VALLEZ
  • Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them
    Patent number: 10138260
    Abstract: Compounds of formula (I) wherein: Ak1 represents an alkyl chain, X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)—, —N(R)—CH2— or —CH2—N(R)—CH2—, m and R are as defined in the description, R1 and R2 each represent H when X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)— or —N(R)—CH2—, or together form a bond when X represents —CH2—N(R)—CH2—, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yl, Cy and Ak3 are as defined in the description, R4 and R5, which may be identical or different, each represent H or F, their optical isomers, and addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating conditions requiring a TAFIa inhibitor.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: November 27, 2018
    Assignee: LES LABORATOIRES SERVIER
    Inventors: Philippe Gloanec, Arnaud-Pierre Schaffner, Patricia Sansilvestri-Morel, Alain Rupin, Philippe Mennecier, Marie-Odile Vallez
  • COMPOUNDS OF PHOSPHINANES AND AZAPHOSPHINANES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20180016288
    Abstract: Compounds of formula (I) wherein: Ak1 represents an alkyl chain, X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)—, —N(R)—CH2— or —CH2—N(R)—CH2—, m and R are as defined in the description, R1 and R2 each represent H when X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)— or —N(R)—CH2—, or together form a bond when X represents —CH2—N(R)—CH2—, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yl, Cy and Ak3 are as defined in the description, R4 and R5, which may be identical or different, each represent H or F, their optical isomers, and addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating conditions requiring a TAFIa inhibitor.
    Type: Application
    Filed: January 13, 2017
    Publication date: January 18, 2018
    Inventors: Philippe GLOANEC, Arnaud-Pierre SCHAFFNER, Patricia SANSILVESTRI-MOREL, Alain RUPIN, Philippe MENNECIER, Marie-Odile VALLEZ
  • Cyclic urea compounds and preparation thereof
    Patent number: 7186828
    Abstract: A method for preparing cyclic urea compounds from at least an activated carbamic acid derivative containing an unprotected primary or secondary amine function, includes a cyclization step which consists in a reaction between the primary or secondary amine function and the carbamic acid function of the carbamic acid derivative(s).
    Type: Grant
    Filed: June 13, 2001
    Date of Patent: March 6, 2007
    Assignee: ImmuPharma (France) SA
    Inventors: Gilles Guichard, Marie-Christine Galas-Rodriguez, legal representative, Pierre Rodriguez, legal representative, Elisa Rodriguez, legal representative, Romain Rodriguez, legal representative, Serge Plaue, Vincent Semetey, Arnaud-Pierre Schaffner, Jean-Paul Briand, Marc Rodriguez, deceased
  • Cyclic urea compounds and preparation thereof
    Publication number: 20040044199
    Abstract: A method for preparing cyclic urea compounds from at least an activated carbamic acid derivative containing an unprotected primary or secondary amine function, includes a cyclization step which consists in a reaction between the primary or secondary amine function and the carbamic acid function of the carbamic acid derivative(s).
    Type: Application
    Filed: June 24, 2003
    Publication date: March 4, 2004
    Inventors: Gilles Guichard, Marc Rodriguez, Serge Plaue, Vincent Semetey, Arnaud-Pierre Schaffner, Jean-Paul Briand