Patents by Inventor Arne Heyerick

Arne Heyerick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODRUGS AND MEDICAL USES THEREOF
    Publication number: 20210205299
    Abstract: The invention relates to nitrogen mustards bearing substituted piperazine carboxamide and their corresponding pharmaceutically acceptable salts as cytotoxic agents that target tumours and methods of use thereof, alone or in combination with other cancer treatments.
    Type: Application
    Filed: May 29, 2019
    Publication date: July 8, 2021
    Inventors: Arne HEYERICK, Sofie DESCHOEMAEKER, Sophie THIOLLOT, Dominique TERSAGO, Philiph LAMBIN
  • Enzymatic demethylation of flavonoids
    Patent number: 8709764
    Abstract: The invention discloses the demethylation of 5-methoxyflavonoids by bacterial enzymes, the use of these enzymes in the production of phytoestrogens in vitro, and in pharmaceutical compositions in combination with a source of methylated 5-methoxyprenylflavonoids.
    Type: Grant
    Filed: March 27, 2006
    Date of Patent: April 29, 2014
    Assignee: Universiteit Gent
    Inventors: Sam Possemiers, Willy Verstraete, Arne Heyerick, Denis De Keukeleire
  • Production of hop extracts having oestrogenic and antiproliferative bioactivity
    Publication number: 20110130447
    Abstract: A method for the production of a hop extract which is enriched in 8-prenylnaringenin with respect to 6-prenylnaringenin include the steps of subjecting a hop product to (1) an isomerisation reaction in the presence of water as a solvent and in the presence of an amount of a base and (2) to at least one extraction. In that way a hop extract is obtained which contains 6-prenylnaringenin and 8-prenylnaringenin in a ratio (8-prenylnaringenin×100%)/(8-prenylnaringenin+6-prenylnaringenin) of at least 50%. The extract preferably also contains xanthohumol, the weight ratio of xanthohumol to 8-prenylnaringenin being at least 10.
    Type: Application
    Filed: October 25, 2010
    Publication date: June 2, 2011
    Inventors: Francis Maes, Denis De Keukeleire, Arne Heyerick
  • Enzymatic Demethylation of Flavonoids
    Publication number: 20090130724
    Abstract: The invention discloses the demethylation of 5-methoxyflavonoids by bacterial enzymes, the use of these enzymes in the production of phytoestrogens in vitro, and in pharmaceutical compositions in combination with a source of methylated 5-methoxyprenylflavonoids.
    Type: Application
    Filed: March 27, 2006
    Publication date: May 21, 2009
    Inventors: Sam Possemiers, Willy Verstraete, Arne Heyerick, Denis De Keukeleire
  • Method for the production of enriched hop extracts having combined oestrogenic and antiproliferative bioactivity
    Publication number: 20070110835
    Abstract: The present invention relates to a method for the production of a hop extract which is enriched in 8-prenylnaringenin with respect to 6-prenylnaringenin, which method comprises the steps of subjecting a hop product to (1) an isomerisation reaction in the presence of water as a solvent and in the presence of an amount of a base and (2) to at least one extraction. In that way a hop extract may be extract is obtained which contains 6-prenylnaringenin and 8-prenylinaringening in a ratio (8-prenylnaringenin ×100%)/(8-prenylnaringenin+6-prenylnaringenin) of at least 50%. The extract preferably also contains xanthohumol, the weight ratio of xanthohumol to 8-prenylnaringenin being at least 10.
    Type: Application
    Filed: December 15, 2004
    Publication date: May 17, 2007
    Inventors: Francis Maes, Denis De Keukeleire, Arne Heyerick