Patents by Inventor Arne Kristensen
Arne Kristensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230009314Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: ApplicationFiled: September 19, 2022Publication date: January 12, 2023Inventors: Anders Axelsson, Arne Kristensen, Henri Hansson
-
Patent number: 11547660Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: GrantFiled: August 27, 2021Date of Patent: January 10, 2023Assignee: Niconovum USA, Inc.Inventors: Anders Axelsson, Arne Kristensen, Henri Hansson
-
Publication number: 20210386662Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: ApplicationFiled: August 27, 2021Publication date: December 16, 2021Inventors: Anders Axelsson, Arne Kristensen, Henri Hansson
-
Patent number: 11129792Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: GrantFiled: November 19, 2018Date of Patent: September 28, 2021Assignee: Modoral Brands Inc.Inventors: Anders Axelsson, Arne Kristensen, Henri Hansson
-
Publication number: 20190083393Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: ApplicationFiled: November 19, 2018Publication date: March 21, 2019Inventors: Anders Axelsson, Arne Kristensen, Henri Hansson
-
Patent number: 10219999Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: GrantFiled: November 30, 2012Date of Patent: March 5, 2019Assignee: Niconovum USA, Inc.Inventors: Anders Axelsson, Arne Kristensen, Henri Hansson
-
Patent number: 9629832Abstract: A nicotine-containing particulate material for release of nicotine, the material comprising a combination of nicotine or a pharmaceutically acceptable salt, complex or solvate thereof and a microcrystalline cellulose, The particulate material is stable upon storage and releases nicotine relatively fast. The particulate material can be used in the manufacture of nicotine-containing pharmaceutical composition, wherein the release of nicotine can be designed to be relatively fast so as to obtain a fast onset of action.Type: GrantFiled: April 28, 2014Date of Patent: April 25, 2017Assignee: Niconovum USA, Inc.Inventors: Henri Hansson, Arne Kristensen
-
Patent number: 9402809Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: GrantFiled: March 16, 2007Date of Patent: August 2, 2016Assignee: Niconovum USA, Inc.Inventors: Anders Axelsson, Arne Kristensen, Henri Hansson
-
Patent number: 8833378Abstract: A method for the preparation of a nicotine-cellulose combination, the method comprising simultaneous loading of the nicotine on the cellulose and agglomeration of the particles so as to obtain a suitably loaded combination with a mean particle size that is suitable for use e.g. in snuff compositions packed in pouches of gauze or other materials with opening. The invention further relates to the use of such a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: GrantFiled: September 17, 2009Date of Patent: September 16, 2014Assignee: Niconovum ABInventors: Anders Axelsson, Arne Kristensen
-
Publication number: 20140234392Abstract: A nicotine-containing particulate material for release of nicotine, the material comprising a combination of nicotine or a pharmaceutically acceptable salt, complex or solvate thereof and a microcrystalline cellulose, The particulate material is stable upon storage and releases nicotine relatively fast. The particulate material can be used in the manufacture of nicotine-containing pharmaceutical composition, wherein the release of nicotine can be designed to be relatively fast so as to obtain a fast onset of action.Type: ApplicationFiled: April 28, 2014Publication date: August 21, 2014Applicant: Niconovum ABInventors: Henri Hansson, Arne Kristensen
-
Patent number: 8741348Abstract: A nicotine-containing particulate material for release of nicotine, the material comprising a combination of nicotine or a pharmaceutically acceptable salt, complex or solvate thereof and a microcrystalline cellulose. The particulate material is stable upon storage and releases nicotine relatively fast. The particulate material can be used in the manufacture of nicotine containing pharmaceutical composition, wherein the release of nicotine can be designed to be relatively fast so as to obtain a fast onset of action.Type: GrantFiled: December 19, 2003Date of Patent: June 3, 2014Assignee: Niconovum ABInventors: Henri Hansson, Arne Kristensen
-
Publication number: 20110214681Abstract: A method for the preparation of a nicotine-cellulose combination, the method comprising simultaneous loading of the nicotine on the cellulose and agglomeration of the particles so as to obtain a suitably loaded combination with a mean particle size that is suitable for use e.g. in snuff compositions packed in pouches of gauze or other materials with opening. The invention further relates to the use of such a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: ApplicationFiled: September 17, 2009Publication date: September 8, 2011Applicant: NicoNovum ABInventors: Anders Axelsson, Arne Kristensen
-
Publication number: 20100260690Abstract: Use of a nicotine-cellulose combination, maltitol and a gum base for the preparation of a chewing gum composition for achieving a fast onset of nicotine effect after initiation of chewing the chewing gum composition by a subject. The chewing gum composition is preferably prepared by direct compression and it does not disintegrate during chewing. The invention also relates to chewing gum compositions comprising nicotine, which compositions provide a rapid release of nicotine.Type: ApplicationFiled: September 18, 2008Publication date: October 14, 2010Inventors: Arne Kristensen, Anders Axelsson, Nils Siegbahn
-
Publication number: 20100061940Abstract: Use of a nicotine-cellulose combination and a gum base for the preparation of a chewing gum composition for achieving a fast onset of nicotine effect after initiation of chewing the chewing gum composition by a subject. The chewing gum composition is preferably prepared by direct compression and it does not disintegrate during chewing. The invention also relates to chewing gum compositions comprising nicotine, which compositions provide a rapid release of nicotine.Type: ApplicationFiled: March 16, 2007Publication date: March 11, 2010Applicant: NicoNovum ABInventors: Anders Axelsson, Henri Hansson, Arne Kristensen
-
Publication number: 20100004294Abstract: Compositions comprising nicotine, which compositions provide a rapid release of nicotine. Nicotine is present in the form of a nicotine-cellulose combination. The compositions are designed for administration to the oral cavity where the nicotine is rapidly released from the composition and available for absorption through the oral mucosa. The compositions are lozenges and have excellent storage stability.Type: ApplicationFiled: September 16, 2007Publication date: January 7, 2010Applicant: NicoNovum ABInventors: Anders Axelsson, Arne Kristensen, Henri Hansson
-
Publication number: 20090293895Abstract: Use of a nicotine-cellulose combination for the preparation of a snuff composition for achievement of a fast onset of action of nicotine after application of the snuff composition to the oral cavity of a subject, wherein the composition has a high release rate so that when subjected to an in vitro dissolution test about 45% or more of the total content of nicotine is released within 30 minutes. Moreover, the invention relates to an improved snuff composition for application to the oral cavity.Type: ApplicationFiled: March 16, 2007Publication date: December 3, 2009Applicant: NicoNovum ABInventors: Anders Axelsson, Arne Kristensen, Henri Hansson
-
Patent number: 5807583Abstract: A process for the manufacture of sustained release pellets comprising pelletizing a mixture containing the drug in finely divided form and a binder. The characteristic feature is that:(a) said binder is in particle form consisting of one or more water-insoluble wax-like binder substance(s) with a melting point above 40.degree. C., and(b) said pelletization step is performed by mechanically working said mixture, in a high shear mixer, under the input of a sufficient amount of energy for the binder to melt and pelletization to take place.Type: GrantFiled: January 12, 1995Date of Patent: September 15, 1998Assignee: Pharmacia ABInventors: Henning Kristensen, Torben Schaefer, Lars Juul Thomsen, deceased, Arne Kristensen
-
Patent number: 5476667Abstract: A melt granulating method for the production of pellets (spheres) which contain a therapeutically active substance of high-dosage type. The method is characterized by: (i) mechanically working a mixture which contains (a) the active substance in cohesive form and (b) a binder (melting point 40.degree. C.-100.degree. C.) while supplying sufficient energy for the binder to melt and to form spherical overwetted pellets; (ii) adding further cohesive substance, while maintaining the mechanical working; (iii) interrupting the mechanical working and supply of energy and cohesive substance when the desired mean particle size of dry pellets (spheres) has been achieved; and (iv) removing the smallest and largest particles and dividing the remaining pellets into dosage batches. A novel pharmaceutical composition containing a dosage of 300-500 mg of pellets is obtainable from this process.Type: GrantFiled: April 16, 1993Date of Patent: December 19, 1995Assignee: Kabi Pharmacia ABInventors: Arne Kristensen, Per Holm