Patents by Inventor Arne Lunding
Arne Lunding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8581021Abstract: The present invention relates to a genetically modified pig comprising at least one site for integration of at least one transgene. The invention also pertains to a porcine embryo, blastocyst, fetus, donor cell and/or cell nucleus, derived from said genetically modified pig. In another aspect, the invention relates to any genetically modified porcine blastocyst, wherein the genetically modified genome comprises at least one site for integration of at least one transgene.Type: GrantFiled: March 7, 2008Date of Patent: November 12, 2013Assignee: Aarhus UniversitetInventors: Jacob Giehm Mikkelsen, Brian Moldt, Anders Lade Nielsen, Lars Axel Bolund, Peter Michael Kragh, Jannik Ejnar Jakobsen, Arne Lund Jørgensen
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Patent number: 8389794Abstract: The present invention relates to a modified pig as a model for studying Alzheimer's disease. The modified pig model displays one or more phenotypes associated with Alzheimer's disease. Disclosed is also a modified pig comprising a modified human and/or porcine APP gene, and/or PS1 gene, and/or a transcriptional and/or translational product or part thereof. The invention further relates to methods for producing the modified pig; and methods for evaluating the effect of a therapeutical treatment of Alzheimer's disease; methods for screening the efficacy of a pharmaceutical composition; and a method for treatment of a human being suffering from Alzheimer's disease are disclosed.Type: GrantFiled: March 6, 2008Date of Patent: March 5, 2013Assignee: Aarhus UniversitetInventors: Arne Lund Jørgensen, Ida Elisabeth Holm, Anders Lade Nielsen, Marianne Gregers Johansen, Jannik Ejnar Jakobsen
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Publication number: 20100179412Abstract: An arrangement for magnetic particle imaging and a method for influencing and/or detecting magnetic particles in a region of action is disclosed, which arrangement comprises: magnetic particles in a region of action, the magnetic particles being influenceable and/or detectable, selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strengthare formed in the region of action, drive means for changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, wherein each magneticparticle comprises a non-magnetic substrate with a layer of stainless steel.Type: ApplicationFiled: February 11, 2008Publication date: July 15, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Jurgen Weizenecker, Bernhard Gleich, Hans Negle, Arne Lunding
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Publication number: 20100154069Abstract: The present invention relates to a genetically modified pig comprising at least one site for integration of at least one transgene. The invention also pertains to a porcine embryo, blastocyst, foetus, donor cell and/or cell nucleus, derived from said genetically modified pig. In another aspect, the invention relates to any genetically modified porcine blastocyst, wherein the genetically modified genome comprises at least one site for integration of at least one transgene.Type: ApplicationFiled: March 7, 2008Publication date: June 17, 2010Applicant: AARHUS UNIVERSITETInventors: Jacob Giehm Mikkelsen, Brian Moldt, Anders Lade Nielsen, Lars Axel Bolund, Peter Michael Kragh, Jannik Ejnar Jakobsen, Arne Lund Jørgensen
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Publication number: 20100138940Abstract: The present invention relates to a modified pig as a model for studying Alzheimer's disease. The modified pig model displays one or more phenotypes associated with Alzheimer's disease. Disclosed is also a modified pig comprising a modified human and/or porcine APP gene, and/or PS1 gene, and/or a transcriptional and/or translational product or part thereof. The invention further relates to methods for producing the modified pig; and methods for evaluating the effect of a therapeutical treatment of Alzheimer's disease; methods for screening the efficacy of a pharmaceutical composition; and a method for treatment of a human being suffering from Alzheimer's disease are disclosed.Type: ApplicationFiled: March 6, 2008Publication date: June 3, 2010Applicant: AARHUS UNIVERSITETInventors: Arne Lund Jorgensen, Ida Elisabeth Holm, Anders Lade Nielsen, Marianne Gregers Johansen, Jannik Ejnar Jakobsen
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Patent number: 7050539Abstract: A power supply for X-ray generators which includes at least one inverter (11, 12, 13), at least one transformer (111, 121, 131) and at least one voltage cascade (112, 122, 132) for generating a supply voltage for an X-ray tube (15). In order to increase the output power that can be achieved with a comparatively small weight and a low ripple or output capacitance, the voltage cascade is conceived in respect of its capacitances and the stray inductance of the transformers (111, 121, 131) in such a manner that it can be made to operate in the resonance mode by appropriate control of the inverter. In respect of the properties mentioned it is notably advantageous to integrate a two-phase embodiment or three-phase embodiment with an X-ray system so as to form a compact tank generator.Type: GrantFiled: December 5, 2002Date of Patent: May 23, 2006Assignee: Koninklijke Philips Electronics N.V.Inventors: Christoph Loef, Arne Lunding, Heiko Osterholz, Heinz Van Der Broeck
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Publication number: 20050018815Abstract: A power supply for X-ray generators which includes at least one inverter (11, 12, 13), at least one transformer (111, 121, 131) and at least one voltage cascade (112, 122, 132) for generating a supply voltage for an X-ray tube (15). In order to increase the output power that can be achieved with a comparatively small weight and a low ripple or output capacitance, the voltage cascade is conceived in respect of its capacitances and the stray inductance of the transformers (111, 121, 131) in such a manner that it can be made to operate in the resonance mode by appropriate control of the inverter. In respect of the properties mentioned it is notably advantageous to integrate a two-phase embodiment or three-phase embodiment with an X-ray system so as to form a compact tank generator.Type: ApplicationFiled: December 5, 2002Publication date: January 27, 2005Inventors: Christoph Loef, Arne Lunding, Heiko Osterholz, Heinz Van Der Broeck
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Patent number: 6703010Abstract: Powder compositions usable to reduce malodours, and powder formulations from which can be made aqueous spray compositions usable to reduce malodours, each comprise, as a major ingredient, amphoteric material, for example sodium bicarbonate, potassium bicarbonate, or zinc oxide, together with one or more minor ingredients, in particular a drying agent, for example sodium sulphate. Other minor ingredients may be an ammonia-odour/sulphide-odour remover, for example ferrous sulphate or zinc sulphate, and an adsorbent, for example zeolite, in the case of a powder formulation; or a filler, for example potassium chloride, or an organic complexing agent, for example cyclodextrin, or a surfactant, in the case of a stock formulation.Type: GrantFiled: May 14, 2001Date of Patent: March 9, 2004Inventors: Jan Frismark, Arne Lund Kvernheim, Ole Widar Saastad, Ronnie Thomasson, Børre Bengt Ulrichsen, Fred Archer
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Patent number: 6672385Abstract: The invention relates to a system and a method for well completion, control and monitoring of processes in a reservoir. A combined prefabricated liner and matrix system (4) with defined properties for fast and simple well and/or reservoir completion, monitoring and control is provided. An embodiment of the combined prefabricated liner and matrix system 4 includes an outer perforated tubular pipe system 6, an inner tubular screen 7, and a matrix 8. A method for control and monitoring of processes in a well or reservoir using the combined liner and matrix system is also described. The combined liner/matrix system may be used in any process equipment, such as reactors, separators and storage tanks. The system may also be used in a gas/oil/water producing or injection well for well completion, control and monitoring.Type: GrantFiled: July 20, 2001Date of Patent: January 6, 2004Assignee: Sinvent ASInventors: Lars Kilaas, Are Lund, Davoud Tayebi, Jostein Sveen, Arne Lund Kvernheim, Marit Valeur Ramstad, Odd Ivar Eriksen, Ole Bernt Lile, Ole Widar Saastad
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Patent number: 6645769Abstract: A method for monitoring hydrocarbon and water production from different production zones/sections in a hydrocarbon reservoir and/or injection wells and detection of different phenomena such as e.g. local variations in pH, salinity, hydrocarbon composition, temperature, pressure, microorganisms, and the difference between production of formation and/or injection water from various zones/sections. The method includes dividing regions around wells in the reservoir into a number of zones/sections, and injecting or placing specific tracers with unique characteristics for each zone/section into the formation in these regions such that tracers are placed as integrated parts of the well completion or placed and immobilized in these regions through injection, squeeze or by other techniques. The tracers can also be immobilized or placed on a filter, a casing or other constructions surrounding the well in each zone/section. The tracers are specific or introduced to give specific information from each zone/section.Type: GrantFiled: November 29, 2000Date of Patent: November 11, 2003Assignee: Sinvent ASInventors: Davoud Tayebi, Lars Kilaas, Are Lund, Arne Lund Kvernheim, Odd Ivar Eriksen, Jostein Sveen, Ole Bernt Lile, Marit Valeur Ramstad, Ole Widar Saastad
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Patent number: 6563717Abstract: The invention relates to a power supply for X-ray generators which includes at least one inverter, at least one transformer and at least one voltage cascade for generating a supply voltage for an X-ray tube. In order to increase the output power that can be achieved while ensuring at the same time a comparatively low weight and a small ripple or output capacitance, the voltage cascade is configured in respect of its capacitances and the stray inductance of the transformers in such a manner that it can operate in the resonance mode under appropriate control of the inverter. For said features it is particularly beneficial to use a two-phase or three-phase configuration which can be integrated with an X-ray system so as to form a compact tank generator.Type: GrantFiled: September 26, 2001Date of Patent: May 13, 2003Assignee: Koninklijke Philips Electronics N.V.Inventors: Arne Lunding, Heiko Osterholz
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Publication number: 20020067631Abstract: The invention relates to a power supply for X-ray generators which includes at least one inverter (11, 12, 13), at least one transformer (111, 131, 131) and at least one voltage cascade (112, 122, 132) for generating a supply voltage for an X-ray tube (15). In order to increase the output power that can be achieved while ensuring at the same time a comparatively low weight and a small ripple or output capacitance, the voltage cascade is configured in respect of its capacitances and the stray inductance of the transformers (111, 131, 131) in such a manner that it can operate in the resonance mode under appropriate control of the inverter. For said features it is particularly beneficial to use a two-phase or three-phase configuration which can be integrated with an X-ray system so as to form a compact tank generator.Type: ApplicationFiled: September 26, 2001Publication date: June 6, 2002Inventors: Arne Lunding, Heiko Osterholz
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Publication number: 20020020527Abstract: The invention relates to a system and a method for well completion, control and monitoring of processes in a reservoir. A combined prefabricated liner and matrix system (4) with defined properties for fast and simple well and/or reservoir completion, monitoring and control is provided. An embodiment of the combined prefabricated liner and matrix system 4 comprises an outer perforated tubular pipe/pipe system 6, an inner tubular screen 7, and a matrix 8. A method for control and monitoring of processes in a well or reservoir using the combined liner and matrix system is also described The combined liner/matrix system may be used in any process equipment, like e.g. reactors, separators and storage tanks. The system may also be used in a gas/oil/water producing or injection well for well completion, control and monitoring.Type: ApplicationFiled: July 20, 2001Publication date: February 21, 2002Inventors: Lars Kilaas, Are Lund, Davoud Tayebi, Jostein Sveen, Arne Lund Kvernheim, Marit Valeur Ramstad, Odd Ivar Eriksen, Ole Bernt Lile, Ole Widar Saastad
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Publication number: 20010036667Abstract: The present invention relates to a method for monitoring the hydrocarbon and water production from different production zones/sections in a hydrocarbon reservoir and/or injection wells and detection of different phenomena such as e.g. local variations in pH, salinity, hydrocarbon composition, temperature, pressure, microorganisms, and the difference between production of formation and/or injection water from various zones/sections. The method comprising dividing regions around wells in the reservoir into a number of zones/sections, and injecting or placing specific tracers with unique characteristics for each zone/section into the formation in these regions such that tracers are placed as integrated parts of the well completion or placed and immobilized in these regions through injection, squeeze or by other techniques. The tracers can also be immobilized or placed on a filter, a casing or constructions surrounding the well in each zone/section.Type: ApplicationFiled: November 29, 2000Publication date: November 1, 2001Inventors: Davoud Tayebi, Lars Kilaas, Are Lund, Arne Lund Kvernheim, Odd Ivar Eriksen, Jostein Sveen, Ole Bernt Lile, Marit Valeur Ramstad, Ole Widar Saastad
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Patent number: 6302983Abstract: A method for renovation of pipelines, comprising introduction of lining layers into the existing pipeline, the lining layers corresponding in length to the length of the pipeline to be renovated. The lining layers consist of fusible polymers and are presurized and fused together by the introduction of a heat source into the inside of the innermost lining layer.Type: GrantFiled: October 28, 1998Date of Patent: October 16, 2001Assignee: Uponor Innovation ABInventors: Lennart Agren, Arne Lund, Alan John Dickinson, Veli-Pekka Jormakka, Bo Mollsjo, Harri Leo, Jyri Jarvenkyla
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Patent number: 6111933Abstract: In an X-ray device which includes an X-ray tube (12) provided with means (15, 22, 23) for influencing the electron flow through the X-ray tube (12), a control voltage for the means for influencing the electron flow is customarily generated by means of a complex circuit which, because of its size, is not suitable to be accommodated within the protective tube housing. This has the drawback that the control voltage for the X-ray tube, usually of high voltage potential, must be supplied additionally to the high-voltage supply. Therefore, it is desirable to realize a simple generation means the control voltage which is suitable for accommodation in the protective tube housing. To this end, the invention proposes a piezoelectric transformer (21, 24, 25) for generating the control voltage for the X-ray tube. The invention also relates to a piezoelectric transformer which is particularly suitable for generating such a control voltage.Type: GrantFiled: January 21, 1998Date of Patent: August 29, 2000Assignee: U.S. Philips CorporationInventors: Uwe Schaaf, Heinz Van Der Broeck, Martin Wimmer, Arne Lunding, Reinhard v. Hacht, Diethard Peter
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Patent number: 5469891Abstract: The invention relates to a material wherein the main constituent is PVC for manufacturing pipes to be used for relining underground pipelines by the pipe in a folded condition being drawn into the pipeline and being engaged with the inside surface of the pipeline by temperature increase. By the addition of polymer thermoplastic elastomers which can be mixed with PVC the material has a glass transition temperature ranging from 45.degree. to 75.degree. C. and a ratio (Emod, T=20.degree. C.)/(Emod, T=75.degree. C.)>20. The invention also relates to a method for restoring underground pipes by relining such pipes with a pipe which has been folded after the extrusion.Type: GrantFiled: April 18, 1994Date of Patent: November 28, 1995Assignee: Uponor Innovation ABInventors: Arne Lund, Lennart Agren
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Patent number: 5408236Abstract: A high-voltage unit comprising at least a high-voltage electrode which carries a high voltage in the operating condition of the high-voltage unit. A measuring divider/resistor arrangement is connected between the high-voltage electrode and a measuring point wherefrom a measuring voltage is derived corresponding to the variation in time of the high voltage. A reduced volume and thus a more compact device is achieved in that a flat measuring electrode is provided which carries the potential of the measuring point and in that the measuring divider/resistor arrangement is positioned between the high-voltage electrode and the measuring electrode so that it is inclined relative to each of these electrodes.Type: GrantFiled: April 9, 1993Date of Patent: April 18, 1995Assignee: U.S. Philips CorporationInventors: Bernd Freiheit-Jensen, Arne Lunding, Hans Negle
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Patent number: 4611432Abstract: In a window comprising a main frame (1), an intermediate frame (3) hinged at the top of the latter and a sash (7) which is journalled as a pivot sash in the intermediate frame, said intermediate frame (3) is provided with an arresting means (5) in the area of the pivoting axis (2), said arresting means normally being engaged with an associate arresting means (6) in the main frame. The arrest can be disengaged by means of a release handle (9) which is placed on the inner side of the main frame (1), and the window can then serve as an emergency exit, as the intermediate frame (3) with the sash (7) is swung clear of the main frame due to a permanent urging of the intermediate frame in its opening direction.Type: GrantFiled: February 11, 1985Date of Patent: September 16, 1986Assignee: V. Kann Rasmussen Industri A/SInventors: Arne Lund, Egon Nowakowski, Elgard Nielsen, Per G. Nielsen