Patents by Inventor Arne Von Bonin

Arne Von Bonin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccine against
    Patent number: 11891413
    Abstract: The present invention relates to a synthetic oligosaccharide of general formula (I): T*-[(—Ux+4—Ux+3—Ux+2—Ux+1—Ux)m—(Vx+2—Vx+1—Vx)1-m-T-O-L-E that is related to Klebsiella pneumoniae serotype O3, O3b and/or O5 lipopolysaccharide and conjugate thereof. Said synthetic oligosaccharide, said conjugate and pharmaceutical composition containing said synthetic oligosaccharide or said conjugate are useful for prevention and/or treatment of diseases associated with Klebsiella pneumoniae. Furthermore, the synthetic oligosaccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against Klebsiella pneumoniae serotype O3, O3b and/or O5 bacteria.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: February 6, 2024
    Assignee: IDORSIA PHARMACEUTICALS LTD
    Inventors: Arun Naini, Daniel Knopp, Bopanna Monnanda, Arne Von Bonin, Claney Lebev Pereira
  • Treatment and prevention of Alzheimer's disease (AD)
    Patent number: 11857568
    Abstract: The invention discloses an aluminium salt for use in the treatment and prevention of dementias associated with ?-amyloid deposition, preferably AD.
    Type: Grant
    Filed: July 8, 2021
    Date of Patent: January 2, 2024
    Assignee: Advantage Therapeutics, Inc.
    Inventors: Markus Mandler, Achim Schneeberger, Wolfgang Zauner, Arne Von Bonin, Frank Mattner, Walter Schmidt
  • VACCINE AGAINST KLEBSIELLA PNEUMONIAE
    Publication number: 20230122752
    Abstract: The present invention relates to a synthetic saccharide of general formula (I) that is related to Klebsiella pneumoniae serotype O1, O2, O2ac, and O8 O-polysaccharide and carbapenem-resistant Klebsiella pneumoniae ST258 O-polysaccharide and conjugate thereof. Said synthetic saccharide, said conjugate and pharmaceutical composition containing said synthetic saccharide or said conjugate are useful for prevention and/or treatment of diseases associated with Klebsiella pneumoniae. Furthermore, the synthetic saccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against Klebsiella pneumoniae bacteria.
    Type: Application
    Filed: August 10, 2022
    Publication date: April 20, 2023
    Inventors: Sharavathi Guddehalli Parameswarappa, Marilda P. Lisboa, Sylvia Oestreich, Jessica Przygodda, Bopanna Monnanda, Arne Von Bonin, Claney Lebev Pereira
  • STABLE VACCINE AGAINST CLOSTRIDIUM DIFFICILE
    Publication number: 20230045939
    Abstract: The present invention relates to a synthetic saccharide of general formulate (I) that is related to Clostridium difficile PS-II cell-surface polysaccharide and conjugate thereof. Said synthetic saccharide, said conjugate and pharmaceutical composition containing said synthetic saccharide or said conjugate are useful for prevention and/or treatment of diseases associated with Clostridium difficile. Furthermore, the synthetic saccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against Clostridium difficile bacteria.
    Type: Application
    Filed: November 22, 2019
    Publication date: February 16, 2023
    Inventors: Madhu EMMADI, Marilda P. LISBOA, Daniel KNOPP, Bopanna MONNANDA, Arne VON BONIN, Claney Lebev PEREIRA
  • Vaccine against
    Patent number: 11479574
    Abstract: The present invention relates to a synthetic saccharide of general formula (I) that is related to Klebsiella pneumoniae serotype O1, O2, O2ac, and O8 O-polysaccharide and carbapenem-resistant Klebsiella pneumoniae ST258 O-polysaccharide and conjugate thereof. Said synthetic saccharide, said conjugate and pharmaceutical composition containing said synthetic saccharide or said conjugate are useful for prevention and/or treatment of diseases associated with Klebsiella pneumoniae. Furthermore, the synthetic saccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against Klebsiella pneumoniae bacteria.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: October 25, 2022
    Assignee: IDORSIA PHARMACEUTICALS LTD
    Inventors: Sharavathi Guddehalli Parameswarappa, Marilda P. Lisboa, Sylvia Oestreich, Jessica Przygodda, Bopanna Monnanda, Arne Von Bonin, Claney Lebev Pereira
  • TREATMENT AND PREVENTION OF ALZHEIMER'S DISEASE (AD)
    Publication number: 20220000908
    Abstract: The invention discloses an aluminium salt for use in the treatment and prevention of dementias associated with ?-amyloid deposition, preferably AD.
    Type: Application
    Filed: July 8, 2021
    Publication date: January 6, 2022
    Inventors: Markus Mandler, Achim Schneeberger, Wolfgang Zauner, Arne Von Bonin, Frank Mattner, Walter Schmidt
  • VACCINE AGAINST KLEBSIELLA PNEUMONIAE
    Publication number: 20210386845
    Abstract: The present invention relates to a synthetic oligosaccharide of general formula (I): T*-[(—Ux+4—Ux+3—Ux+2—Ux+1—Ux)m—(Vx+2—Vx+1—Vx)1-m-T-O-L-E that is related to Klebsiella pneumoniae serotype O3, O3b and/or O5 lipopolysaccharide and conjugate thereof. Said synthetic oligosaccharide, said conjugate and pharmaceutical composition containing said synthetic oligosaccharide or said conjugate are useful for prevention and/or treatment of diseases associated with Klebsiella pneumoniae. Furthermore, the synthetic oligosaccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against Klebsiella pneumoniae serotype O3, O3b and/or O5 bacteria.
    Type: Application
    Filed: November 30, 2018
    Publication date: December 16, 2021
    Inventors: Arun Naini, Daniel Knopp, Bopanna Monnanda, Arne Von Bonin, Claney Lebev Pereira
  • Treatment and prevention of alzheimer's disease (AD)
    Patent number: 11065273
    Abstract: The invention discloses an aluminium salt for use in the treatment and prevention of dementias associated with ?-amyloid deposition, preferably AD.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: July 20, 2021
    Assignee: AFFIRIS AG
    Inventors: Markus Mandler, Achim Schneeberger, Wolfgang Zauner, Arne Von Bonin, Frank Mattner, Walter Schmidt
  • VACCINE AGAINST KLEBSIELLA PNEUMONIAE
    Publication number: 20210198304
    Abstract: The present invention relates to a synthetic saccharide of general formula (I) that is related to Klebsiella pneumoniae serotype O1, O2, O2ac, and O8 O-polysaccharide and carbapenem-resistant Klebsiella pneumoniae ST258 O-polysaccharide and conjugate thereof. Said synthetic saccharide, said conjugate and pharmaceutical composition containing said synthetic saccharide or said conjugate are useful for prevention and/or treatment of diseases associated with Klebsiella pneumoniae. Furthermore, the synthetic saccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against Klebsiella pneumoniae bacteria.
    Type: Application
    Filed: November 30, 2018
    Publication date: July 1, 2021
    Inventors: Sharavathi Guddehalli Parameswarappa, Marilda P. Lisboa, Sylvia Oestreich, Jessica Przygodda, Bopanna Monnanda, Arne Von Bonin, Claney Lebev Pereira
  • Treatment of Alzheimer's disease (AD) with aluminum oxyhydroxide
    Patent number: 10478454
    Abstract: The invention discloses aluminium oxyhydroxide for use in the treatment and prevention of AD.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: November 19, 2019
    Assignee: AFFIRIS AG
    Inventors: Markus Mandler, Achim Schneeberger, Arne Von Bonin, Frank Mattner, Walter Schmidt
  • METHOD FOR VACCINATION AGAINST A SELF-ANTIGEN IN A HUMAN PATIENT
    Publication number: 20190091306
    Abstract: Disclosed is a method for vaccination against a self-antigen in a human patient wherein a dose with an effective amount of a self-antigen is administered to the patient to elicit a primary immune response, characterised in that the patient is subjected to a boost administration of said self-antigen, wherein the amount of the self-antigen in the dose for the boost administration is higher than the amount of the self-antigen in the dose used in the administration for the primary immune response.
    Type: Application
    Filed: November 2, 2016
    Publication date: March 28, 2019
    Applicant: AFFIRIS AG
    Inventors: Gergana GALABOVA, Sabine SCHMIDHUBER, Achim SCHNEEBERGER, Arne VON BONIN, Dorian WINTER, Jana ZIMMERMANN
  • Method for detecting aSyn-specific antibodies in a biological sample
    Patent number: 9964547
    Abstract: Disclosed is a method for detecting aSyn-specific antibodies in a biological sample, comprising the following steps: —contacting the sample with aSyn-comprising-aggregates and allowing the aSyn-specific antibodies to bind to the aSyn-comprising-aggregates, and —detecting the aSyn-specific antibodies bound to the aSyn-comprising-aggregates by a single particle detection technique, preferably by fluorescence activated cell sorting (FACS).
    Type: Grant
    Filed: April 2, 2014
    Date of Patent: May 8, 2018
    Assignee: AFFIRIS AG
    Inventors: Guenther Staffler, Markus Mandler, Andreas Mairhofer, Arne Von Bonin
  • TREATMENT AND PREVENTION OF ALZHEIMER'S DISEASE (AD)
    Publication number: 20170049812
    Abstract: The invention discloses aluminium oxyhydroxide for use in the treatment and prevention of AD.
    Type: Application
    Filed: April 29, 2015
    Publication date: February 23, 2017
    Applicant: AFFIRIS AG
    Inventors: Markus MANDLER, Achim SCHNEEBERGER, Arne VON BONIN, Frank MATTNER, Walter SCHMIDT
  • METHOD FOR DETECTING ASYN-SPECIFIC ANTIBODIES IN A BIOLOGICAL SAMPLE
    Publication number: 20160054333
    Abstract: Disclosed is a method for detecting aSyn-specific antibodies in a biological sample, comprising the following steps: contacting the sample with aSyn-comprising-aggregates and allowing the aSyn-specific antibodies to bind to the aSsyn-comprising-aggregates, and detecting the aSyn-specific antibodies bound to the aSyn-comprising-aggregates by a single particle detection technique, preferably by fluorescence activated cell sorting (FACS).
    Type: Application
    Filed: April 2, 2014
    Publication date: February 25, 2016
    Applicant: AFFIRIS AG
    Inventors: Guenther STAFFLER, Markus MANDLER, Andreas MAIRHOFER, Arne VON BONIN
  • DENTRIC POLYGLYCEROL SULFATES AND SULFONATES AND THEIR USE FOR INFLAMMATORY DISEASES
    Publication number: 20140363507
    Abstract: The present invention relates to the novel compound classes of dendritic polyglycerol sulfates and sulfonates as well as to their production and use for the treatment of diseases, particularly inflammatory diseases, and to their use as selectin inhibitors and selectin indicators. The dendritic polyglycerol sulfates and sulfonates are also suitable for imaging diagnostics, particularly with respect to inflammatory diseases.
    Type: Application
    Filed: August 26, 2014
    Publication date: December 11, 2014
    Applicant: FREIE UNIVERSITAT BERLIN
    Inventors: Rainer HAAG, Jens DERNEDDE, Rudolf TAUBER, Gesche BERNHARD, Sven ENDERS, Heidemarie WEINHART, Arne VON BONIN, Ulrich ZÜGEL, Holger TÜRK
  • Sulphone-substituted quinazoline derivatives as immuno-modulators, their preparation and use as medicaments
    Patent number: 8841311
    Abstract: The present invention relates to sulphone-substituted quinazoline derivatives of the formula (I), processes for their preparation and their use as a medicament for the treatment of various diseases.
    Type: Grant
    Filed: July 18, 2009
    Date of Patent: September 23, 2014
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Bernd Buchmann, Dirk Kosemund, Duy Nguyen, Arne Von Bonin
  • OXO-SUBSTITUTED IMIDAZO[1,2B]PYRIDAZINES, THEIR PREPARATION AND USE AS PHARMACEUTICALS
    Publication number: 20140135323
    Abstract: The invention relates to novel inhibitors of kinases of the general formula (I): in which Q and R1 are defined in the claims, method for preparing such inhibitors, intermediates for preparing such inhibitors and uses of such inhibitors.
    Type: Application
    Filed: January 17, 2014
    Publication date: May 15, 2014
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Olaf PRIEN, Knut EIS, Benjamin BADER, Judith GUENTHER, Arne VON BONIN
  • Oxo-substituted imidazo[1,2B]pyridazines, their preparation and use as pharmaceuticals
    Patent number: 8653076
    Abstract: The invention relates to novel inhibitors of kinases of the general formula (I): in which Q and R1 are defined in the claims, method for preparing such inhibitors, intermediates for preparing such inhibitors and uses of such inhibitors.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: February 18, 2014
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Olaf Prien, Knut Eis, Benjamin Bader, Judith Guenther, Arne Von Bonin
  • DENTRIC POLYGLYCEROL SULFATES AND SULFONATES AND THEIR USE FOR INFLAMMATORY DISEASES
    Publication number: 20120328519
    Abstract: The present invention relates to the novel compound classes of dendritic polyglycerol sulfates and sultanates as well as to their production and use for the treatment of diseases, particularly inflammatory diseases, and to their use as selectin inhibitors and selectin indicators. The dendritic polyglycerol sulfates and sulfonates are also suitable for imaging diagnostics, particularly with respect to inflammatory diseases.
    Type: Application
    Filed: August 3, 2007
    Publication date: December 27, 2012
    Inventors: Rainer Haag, Jens Dernedde, Rudolf Tauber, Gesche Bernhard, Sven Enders, Heidemarie Weinhart, Arne Von Bonin, Ulrich Zügel, Holger Türk
  • 2-arylthiazole-4-carboxamide derivatives, their preparation and use as pharmaceuticals
    Patent number: 8163739
    Abstract: The present invention relates to 2-arylthiazole-4-carboxamide derivatives of the formula (I), the use thereof as medicament for the treatment of various disorders, and processes for the preparation thereof
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: April 24, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Ulrich Bothe, Arne Von Bonin, Duy Nguyen, Ulf Bomer, Judith Guenther