Patents by Inventor Arnold Caplan

Arnold Caplan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7192719
    Abstract: Whether or not a sample of skin or of a skin equivalent contains such amount of a papillary fibroblast population as to be considered a normal skin is determined by labelling said skin or skin equivalent with at least one antibody specific for papillary fibroblasts and evaluating the extent of such labelling as a marker for skin or skin equivalent quality.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: March 20, 2007
    Assignee: L'Oreal
    Inventors: Daniel Asselineau, Arnold Caplan
  • Publication number: 20060263336
    Abstract: In certain aspects, the invention relates to cell delivery compositions comprising a progenitor cell and a targeting moiety, and methods related thereto. Such compositions and methods may be used, for example, in administering a targeted cell therapy to a subject.
    Type: Application
    Filed: March 22, 2004
    Publication date: November 23, 2006
    Inventor: Arnold Caplan
  • Publication number: 20040082016
    Abstract: Whether or not a sample of skin or of a skin equivalent contains such amount of a papillary fibroblast population as to be considered a normal skin is determined by labelling said skin or skin equivalent with at least one antibody specific for papillary fibroblasts and evaluating the extent of such labelling as a marker for skin or skin equivalent quality.
    Type: Application
    Filed: July 15, 2003
    Publication date: April 29, 2004
    Inventors: Daniel Asselineau, Arnold Caplan
  • Publication number: 20010036642
    Abstract: Whether or not a sample of skin or of a skin equivalent contains such amount of a papillary fibroblast population as to be considered a normal skin is determined by labelling said skin or skin equivalent with at least one antibody specific for papillary fibroblasts and evaluating the extent of such labelling as a marker for skin or skin equivalent quality.
    Type: Application
    Filed: November 29, 2000
    Publication date: November 1, 2001
    Inventors: Daniel Asselineau, Arnold Caplan
  • Patent number: 4609551
    Abstract: A process for exposing live cells to a soluble bone protein and transferring the cells into appropriate skeletal sites to initiate or enhance local chondrogenesis or osteogenesis. Isogenic fibroblasts are exposed in vitro to a soluble bone protein capable of stimulating in vitro and/or in vivo a chondrogenic response. The fibroblasts are then transferred in vivo in a manner effective to prevent diffusion away from the implantation site so that the desired chondro/osteogenesis reaction can proceed. Delivery systems include: combining the activated fibroblasts with a biodegradable matrix; suspending the activated fibroblasts in a solution suitable for intra-articular injection; and attaching the fibroblasts to allografts and prosthetic devices.
    Type: Grant
    Filed: March 20, 1984
    Date of Patent: September 2, 1986
    Inventors: Arnold Caplan, Glenn T. Syftestad
  • Patent number: 4608199
    Abstract: A process of extracting and purifying a bone protein capable of stimulating chondrogenic expression in undifferentiated cells in culture. The purification process is monitored at various stages by bioassaying the bone protein for chondrogenic activity in embryonic limb bud mesenchymal cell cultures.
    Type: Grant
    Filed: March 20, 1984
    Date of Patent: August 26, 1986
    Inventors: Arnold Caplan, Glenn T. Syftestad