Abstract: A valve is provided for controlling the flow of fluid through a flexible conduit such as a length of flexible tubing. The valve includes means for exerting a force against the tubing to deform the tubing and cut off flow therethrough. The force is applied in a direction perpendicular to the flow of axis of the tubing to provide an opposing force to the internal fluid pressure which is equal at any given fluid pressure for either flow direction through the tubing. Movable means are also provided to restrain the means for exerting a force against the tubing in a closed position wherein the flow is cut off. The valve also employs a base member, means for locating the tubing adjacent the base member, and compression means for exerting the perpendicular force against the tubing. An embodiment which permits remote control of the valve is also provided.