Patents by Inventor Arnold Gruenweller

Arnold Gruenweller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Effective and stable DNA enzymes
    Publication number: 20060122136
    Abstract: The present invention relates to DNA enzymes of type 10-23 with certain modifications of specific nucleotides in the core sequence rendering the DNA enzymes particularly stable and additionally exhibiting substantially the same or a higher cleavage efficiency with respect to their substrate when compared against the corresponding unmodified DNA enzymes. The present application further provides host cells containing the DNA enzymes according to the invention. In addition there is provided a pharmaceutical formulation which contains the DNA enzymes or host cells according to the invention. The DNA enzymes and further subjects are directed in particular against the vanilloid receptor 1 (VR1), or picornaviruses. The present invention further provides small interference RNA molecules (siRNA) directed against VR1, and host cells containing the siRNA.
    Type: Application
    Filed: May 6, 2005
    Publication date: June 8, 2006
    Applicant: Gruenenthal GmbH
    Inventors: Steffen Schubert, Jens Kurreck, Arnold Gruenweller, Volker Erdmann