Patents by Inventor Arnold I. Freeman

Arnold I. Freeman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100113335
    Abstract: The present invention discloses lentogenic viral strains useful in the treatment of cancer. A preferred viral strain of Newcastle disease Virus (NDV) is specifically characterized in terms of biological activities. The present invention further discloses treatment of cancer by application of a clonal NDV strain to tumors. According to an alternative preferred embodiment the use of at least one isolated viral protein or subunit or analog thereof, or an isolated polynucleotide encoding same, is used in the treatment of cancer.
    Type: Application
    Filed: October 16, 2009
    Publication date: May 6, 2010
    Inventors: Zichria Zakay-Rones, Amos Panet, Evgeniya Greenbaum, Eithan Galun, Arnold I. Freeman, Linda Rasooly, Charles S. Irving
  • Patent number: 7615209
    Abstract: The present invention discloses methods for inducing regression of a tumor in a subject by administering a pharmaceutical composition comprising a lentogenic strain of Newcastle disease virus (NDV). A preferred viral strain of NDV for inducing regression of a tumor in a subject is a clonal strain of NDV, the NDV HUJ. The methods of the present invention are particularly useful for inducing regression of tumors in patients unresponsive to conventional anti-cancer therapies.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: November 10, 2009
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem, Theravir Management L.P.
    Inventors: Zichria Zakay-Rones, Amos Panet, Evgeniya Greenbaum, Eithan Galun, Arnold I. Freeman, Linda Rasooly, Charles S. Irving
  • Patent number: 5876728
    Abstract: The invention is a method of treating cancer comprising administering an effective amount of either a composition of three herbal extracts consisting essentially of 30% to 70% by weight Goldenseal, 20% to 40% by weight of Myrtle, and 5% to 20% by weight of Centaurea, or a composition of seven herbal extracts consisting essentially of 3% to 5% by weight Centaurea, 1.5% to 4% by weight Capsicum, 1.5% to 4% by weight Lobelia, 20% to 40% by weight Myrrh, 30% to 50% by weight Echinacea, 15% to 25% by weight Goldenseal, and 3% to 5% by weight Myrtle. The compositions were prepared by separately extracting each herb by mixing the herb in water, ethyl alcohol, or a mixture of water and ethyl ether, boiling and cooling the mixture, allowing the mixture to stand for about two weeks, filtering the mixture to obtain the liquid phase, and combining each of said extracts to obtain said compositions.
    Type: Grant
    Filed: January 31, 1996
    Date of Patent: March 2, 1999
    Assignee: Howard David Kass
    Inventors: Howard David Kass, Arnold I. Freeman, Albert Leyva