Abstract: The present invention relates to an improved method of imaging cardiac neurotransmission in vivo in a human subject using adrenergic imaging agents. The method comprises obtaining two separate images with the same adrenergic imaging agent. One of the images is obtained in conjunction with the administration of a compound known to interfere with the uptake of the particular imaging agent in question. Comparison of the two images enables additional information to be obtained in relation to the status of cardiac neurotransmission in said subject compared with imaging with adrenergic imaging agent alone. The invention also provides a method of imaging cardiac neurotransmission in a human subject in vivo wherein a single image is obtained using an adrenergic imaging agent in conjunction with the administration of a non-pharmaceutical dose of an agent known to interfere with the uptake of the imaging agent.

Abstract: A self-administrable anti-fertility composition comprising a progestational compound in an amount effective for alteration of cervical mucus secretions in a manner unfavorable to fertility without systemic absorption and a pharmaceutically acceptable vehicle. A typical composition is a foamable aqueous emulsion containing an anionic surfactant, propylene glycol and an amount of progesterone effective to provide a dose of from about 10 micrograms to about 5 milligrams. The composition may be foamed by dispensing with a syringe or by dispensing from an aerosol container.

Abstract: A self-administrable anti-fertility composition comprising a progestational compound in an amount effective for alteration of cervical mucus secretions in a manner unfavorable to fertility without systemic absorption and a pharmaceutically acceptable vehicle. A typical composition is a foamable aqueous emulsion containing an anionic surfactant, propylene glycol and an amount of progesterone effective to provide a dose of from about 10 micrograms to about 5 miligrams. The composition may be foamed by dispensing with a syringe or by dispensing from an aerosol container.