Patents by Inventor Arnold Leonard Jozef Gielkens

Arnold Leonard Jozef Gielkens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant pseudorabies virus, and vaccines containing the same
    Patent number: 5695765
    Abstract: The invention relates to a pseudorabies virus (PRV) not found in nature and having a genome containing a mutation in the protein kinase gene region and/or in the 28K gene region. The mutation is e.g. a nucleic acid substitution, deletion, insertion or inversion, or a combination thereof. The mutations are introduced, by genetic engineering techniques, into the genome of a naturally occuring PRV, preferably NIA-3. Insertions may be nucleic acid sequences encoding antigenic polypeptides characteristic of a pathogen found in pigs. The invention also relates to vaccines containing a pseudorabies virus according to the invention, and to a process for preparing such vaccines.
    Type: Grant
    Filed: January 25, 1995
    Date of Patent: December 9, 1997
    Assignee: Stichting Voor de Technische Wetenschappen
    Inventors: Niels De Wind, Maria Madalene Van Zijl, Arnold Leonard Jozef Gielkens, Antonius Jozef Maria Berns