Abstract: Suggested are compositions comprising substituted azacycles on one hand and physiological cooling or warming agents, flavors and/or fragrances on the other for masking, enhancing and/or boosting flavors, improving soothing ability, and improving antimicrobial stability.

Abstract: The invention relates to aroma preparations that contain (a) a compound of the formula (I) in which R1 represents a linear or branched, saturated or unsaturated hydrocarbon group with 1 to 4 carbon atoms, R2 represents hydrogen or a hydroxyl group and R3 represents hydrogen, a methyl or methoxy group, or an essential oil containing one or more compounds of the formula (I) and at least one menthol compound.

Abstract: Suggested is a cooling preparation comprising phenylalkenals and homovanillic acid esters.

Abstract: The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.

Abstract: The present invention relates to oral care compositions for altering the composition of oral biofilms so that the proportion of microorganisms, which are detrimental to oral health, is reduced while the proportion of health-promoting microorganisms is increased. Furthermore, oral care products comprising the composition according to the invention in an amount sufficient to alter the composition of oral biofilms to promote dental health are provided.

Abstract: Mixtures comprising a selected cooling active ingredient (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide and at least one other substance which acts as a solvent for (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide, wherein the substance is selected form the group consisting of benzyl benzoate, diethyl succinate, triethyl citrate, triacetin, ethanol, peppermint oil, anethol, optamint, propylene glycol, further cooling active ingredients or mixtures thereof.

Abstract: The invention relates to coolant mixtures containing: (a) at least one compound of formula (I), (b) at least one compound of formula (II) in which R1 stands for hydrogen or a methyl group, R2 stands for a methyl, ethyl or propyl group and n stands for 0, 1, or 2, and if applicable (c) an additional component.

Abstract: Suggested are liquid cooling compositions, containing (a) L-Menthol, (b) D-Menthol, and (c) at least one further cooling agent, selected from the group consisting of isomenthol, menthyl acetate (L), menthyl acetate (D), menthyl acetate (iso), acetic acid menthyl lactate (iso) and acetic acid menthyl lactate (neo) with the proviso that in case that component (c) represents Isomenthol, the compositions do not contain any alkanediols.

Abstract: The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.

Abstract: The invention relates to coolant mixtures containing: (a) at least one compound of formula (I), (b) at least one compound of formula (II) in which R1 stands for hydrogen or a methyl group, R2 stands for a methyl, ethyl or propyl group and n stands for 1 or 2, and if applicable, (c) an additional coolant.

Abstract: Suggested is a composition comprising (a) at least one lactate ester and (b1) at least one second compound selected from the group encompassing benzaldehyde derivatives, aromatic aldehydes and aromatic acids.

Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

Abstract: The invention relates to aroma preparations that contain (a) a compound of the formula (I) in which R1 represents a linear or branched, saturated or unsaturated hydrocarbon group with 1 to 4 carbon atoms, R2 represents hydrogen or a hydroxyl group and R3 represents hydrogen, a methyl or methoxy group, or an essential oil containing one or more compounds of the formula (I) and at least one menthol compound.

Abstract: Suggested are liquid cooling compositions, containing (a) L-Menthol, (b) D-Menthol, and (c) at least one further cooling agent, selected from the group consisting of isomenthol, menthyl acetate (L), menthyl acetate (D), menthyl acetate (iso), acetic acid menthyl lactate (iso) and acetic acid menthyl lactate (neo) with the proviso that in case that component (c) represents Isomenthol, the compositions do not contain any alkanediols.

Abstract: Mixtures comprising a selected cooling active ingredient (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide and at least one other substance which acts as a solvent for (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide, wherein the substance is selected form the group consisting of benzyl benzoate, diethyl succinate, triethyl citrate, triacetin, ethanol, peppermint oil, anethol, optamint, propylene glycol, further cooling active ingredients or mixtures thereof.

Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

Abstract: A mixtures which contain (a) at least one phenylalkenal of formula (I) wherein R1 and R2 independently represent hydrogen, a methyl or phenyl group, R3 represents hydrogen, a phenyl group, alkenyl group or a linear or branched alkyl group with 1 to 5 carbon atoms, and the broken double lines independently represent a single bond or a double bond, and (b) at least one physiological cooling agent.

Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

Abstract: The present invention primarily concerns teeth cleaning compounds containing menthol for use with a toothbrush, preferably tooth pastes, tooth crèmes, tooth cleaning gels or tooth powders. Such a tooth cleaning compound according to the invention contains menthol and a quantity, for masking the bitterness of the menthol, of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the following formula (Ia), in particular of the following formula (Ib), i.e. L-menthane carboxylic acid-N-(4-methoxyphenyl)-amide. The present invention also concerns the use of menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) of the formulas (Ia) or (preferably) (Ib) to mask the bitter taste of menthol in a teeth cleaning compound. The present invention also concerns a method for dissolving menthane carboxylic acid-N-(4-methoxyphenyl)-amide (WS-12) in a teeth cleaning compound and a method for masking the bitterness of menthol in a teeth cleaning compound.

Abstract: Suggested is a composition comprising (a) at least one lactate ester and (b1) at least one second compound selected from the group encompassing benzaldehyde derivatives, aromatic aldehydes and aromatic acids.