Patents by Inventor Arnold Paessens

Arnold Paessens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyrazolamides and their use
    Patent number: 8314089
    Abstract: The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: November 20, 2012
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Rudolf Schohe-Loop, Reinhold Welker, Arnold Paessens, Marcus Bauser, Friederike Stoll, Frank Dittmer, Kerstin Henninger, Daniela Paulsen, Dieter Lang
  • SUBSTITUTED PYRAZOLAMIDES AND THEIR USE
    Publication number: 20110172207
    Abstract: The present invention relates to novel substituted pyrazolamides, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: September 16, 2010
    Publication date: July 14, 2011
    Applicant: AiCuris Gmbh & Co. KG
    Inventors: Rudolf SCHOHE-LOOP, Reinhold Welker, Arnold Paessens, Marcus Bauser, Friederike Stoll, Frank Dittmer, Kerstin Henninger, Daniela Paulsen, Dieter Lang
  • SUBSTITUTED AMINOFURANONES AND THEIR USE
    Publication number: 20100105673
    Abstract: The present invention relates to novel substituted aminofurans, to methods for their preparation, to their use in the treatment and/or prophylaxis of diseases as well as their use in the manufacture of medical products for the treatment and/or prophylaxis of diseases, in particular retroviral disorders, in humans and/or animals.
    Type: Application
    Filed: December 8, 2007
    Publication date: April 29, 2010
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Adrian Tersteegen, Dirk Heimbach, Kai Thede, Reinhold Welker, Beate Fast, Arnold Paessens, Frank Dittmer, Rudolf Schohe-Loop, Axel Harrenga, Alexander Hillisch, Kerstin Henninger, Walter Hübsch, Marcus Bauser, Susanne Greschat, Dirk Schneider, Tobias Marquardt, Andreas Göller, Andreas Urban, Steffen Wildum, Daniela Paulsen
  • BIPHENYL SUBSTITUTED SPIROTETRONIC ACIDS AND THEIR USE FOR THE TREATMENT OF RETROVIRAL DISEASES
    Publication number: 20100022527
    Abstract: The present invention relates to novel substituted spirotetronic acids (I) in which R1 and R2, together with the carbon atom to which they are bonded, form a group of the formula (1), (2), (3) or (4), whereby * represents the carbon atom to which R1 and R2 are bonded, to methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of retroviral disorders, in people and/or animals.
    Type: Application
    Filed: February 25, 2009
    Publication date: January 28, 2010
    Applicant: AiCuris GMBH & Co. KG
    Inventors: Dirk HEIMBACH, Adrian TERSTEEGEN, Kai THEDE, Reinhold WELKER, Beate FAST, Arnold PAESSENS, Frank DITTMER, Rudolph SCHOHE-LOOP, Axel HARRENGA, Alexander HILLISCH, Kerstin HENNINGER, Walter HUEBSCH, Marcus BAUSER, Daniela PAULSEN, Alexander BIRKMANN, Thomas BRETSCHNEIDER, Reiner FISCHER, Susanne GRESCHAT, Andreas URBAN, Steffen WILDUM
  • Dihydropyrimidines
    Publication number: 20070117812
    Abstract: The invention relates to compounds of the formulae
    Type: Application
    Filed: December 15, 2006
    Publication date: May 24, 2007
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jurgen Stoltefuss, Siegfried Goldmann, Thomas Kramer, Karl-Heinz Schlemmer, Ulrich Niewohner, Maria Niewohner, Arnold Paessens, Erwin Graef, Stefan Lottmann, Karl Deres, Olaf Weber, Jorn Stolting
  • Medicaments against viral diseases
    Patent number: 7074784
    Abstract: Novel dihydropyrimidines and combinations thereof with other antiviral agents, suitable for combating HBV infections.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: July 11, 2006
    Inventors: Siegfried Goldmann, Jurgen Stoltefuss, Maria Niewohner, legal representative, Karl-Heinz Schlemmer, Jorg Keldenich, Arnold Paessens, Erwin Graef, Olaf Weber, Karl Deres, Ulrich Niewohner, deceased
  • Dihydropyrimidines
    Publication number: 20040167135
    Abstract: The invention relates to compounds of the general formulae (I) and (Ia) 1
    Type: Application
    Filed: February 17, 2004
    Publication date: August 26, 2004
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jurgen Stoltefuss, Siegfried Goldmann, Thomas Kramer, Karl-Heinz Schlemmer, Ulrich Niewohner, Arnold Paessens, Erwin Graef, Stefan Lottmann, Karl Deres, Olaf Weber, Jorn Stolting
  • Replication assay for detecting anti-viral substances
    Publication number: 20040053220
    Abstract: The present invention relates to a replication assay for detecting antivirally effective inhibitors as a single-tube assay, comprising the combination of a natural virus isolate, suspended target cells and cell culture medium containing foetal calf serum, in which the foetal calf serum concentration is less than 5% by volume.
    Type: Application
    Filed: June 16, 2003
    Publication date: March 18, 2004
    Inventors: Arnold Paessens, Frank Dittmer
  • Dihydropyrimidines
    Patent number: 6696451
    Abstract: The invention relates to compounds of the general formulae (I) and (Ia) The invention furthermore relates to processes for preparing the compounds of the formulae (I) and (Ia) and to their use as medicaments, in particular for the treatment and prophylaxis of hepatitis B.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: February 24, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Siegfired Goldmann, Thomas Krämer, Karl-Heinz Schlemmer, Ulrich Niewöhner, Arnold Paessens, Erwin Graef, Stefan Lettmann, Karl Deres, Olaf Weber, Jörn Stölting
  • Medicaments against viral diseases
    Publication number: 20030232842
    Abstract: Novel dihydropyrimidines and combinations thereof with other antiviral agents, suitable for combating HBV infections.
    Type: Application
    Filed: March 10, 2003
    Publication date: December 18, 2003
    Inventors: Siegfried Goldmann, Jurgen Stoltefuss, Ulrich Niewohner, Karl-Heinz Schlemmer, Jorg Keldenich, Arnold Paessens, Erwin Graef, Olaf Weber, Karl Deres
  • Medicament for viral diseases
    Publication number: 20030187028
    Abstract: Isoxazoles are highly effective anti-viral agents. Combinations of isoxazoles, dihydropyrimidines and/or lamivudine and, optionally, interferon inhibit the proliferation of HBV viruses better than conventional agents.
    Type: Application
    Filed: January 21, 2003
    Publication date: October 2, 2003
    Inventors: Michael Brands, Susanne Nikolic, Peter Eckenberg, Marcus Bauser, Johannes Kaulen, Arnold Paessens, Erwin Graef, Olaf Weber, Stefan Lottmann, Karl-Heinz Schlemmer
  • 2-heterocyclically substituted dihydropyrimidines
    Patent number: 6503913
    Abstract: The invention relates to new 2-heterocyclically substituted dihydropyrimidines, medicaments which contain these 2-heterocyclically substituted dihydropyrimidines, and a process for preparation of medicaments. The invention furthermore relates to the use of the 2-heterocyclically substituted dihydropyrimidines for the production of a medicament, in particular for the treatment of acute or chronic viral diseases, in particular for the production of a medicament for the treatment of acute or chronic hepatitis B infections.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: January 7, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Siegfried Goldmann, Jürgen Stoltefuss, Arnold Paessens, Erwin Graef, Stefan Lottmann
  • Use of dihydropyrimidines as medicaments, and novel substances
    Patent number: 6436943
    Abstract: The invention relates to dihydropyrimidines of the general formula and to the use of dihydropyrimidines as medicaments for the treatment and prophylaxis of hepatitis B. The invention further relates to a process for the preparation of medicaments comprising the corresponding dihydropyrimidines.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: August 20, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Stoltefuss, Siegfried Goldmann, Arnold Paessens, Erwin Graef, Stefan Lottmann
  • Medicaments for viral diseases
    Publication number: 20020082264
    Abstract: Chromanone derivatives are highly active antiviral agents. Combinations of chromanones and/or chromanols with HBV polymerase inhibitors, HBV DNA inhibitors or HBV core protein inhibitors and/or isoxazoles and, where appropriate, interferon inhibit the replication of HBV viruses better than agents disclosed previously.
    Type: Application
    Filed: August 30, 2001
    Publication date: June 27, 2002
    Inventors: Susanne Nikolic, Stephan Bartel, Michael Brands, Ulrich Niewohner, Arnold Paessens, Erwin Graef, Karl-Heinz Schlemmer, Kerstin Henninger, Rainer Endermann, Olaf Weber, Diana Koletzki
  • Inhibitors of retroviral proteases
    Patent number: 5712417
    Abstract: The present invention relates to compounds of the formula I ##STR1## wherein A, Y, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, l, m and the corresponding radicals labeled with * are defined as stated in the description, a process for their preparation and their use for the inhibition of retroviral proteases.
    Type: Grant
    Filed: July 11, 1994
    Date of Patent: January 27, 1998
    Assignee: Abbott Laboratories
    Inventors: Karl-Heinz Budt, Bernd Stowasser, Dieter Ruppert, Christoph Meichsner, Arnold Paessens, Jutta Hansen, Jochen Knolle
  • Pseudopeptides with antiviral activity
    Patent number: 5646121
    Abstract: The present invention relates to novel pseudopeptides with antiviral activity of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to a process for their preparation, and to their use as antiviral agents, especially against cytomegaloviruses.
    Type: Grant
    Filed: September 7, 1994
    Date of Patent: July 8, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter Habich, Thomas-J. Schulze, Jurgen Reefschlager, Jutta Hansen, Rainer Neumann, Gert Streissle, Arnold Paessens
  • Valine-containing pseudopeptides with antiviral activity
    Patent number: 5633231
    Abstract: The present invention relates to valine-containing, substituted pseudopeptides of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to processes for their preparation, and to their use as anti-viral agents, in particular against cytomegaloviruses.
    Type: Grant
    Filed: September 7, 1994
    Date of Patent: May 27, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter Habich, Thomas J. Schulze, Jurgen Reefschlager, Jutta Hansen, Rainer Neumann, Gert Streissle, Arnold Paessens
  • Trifluoromethyl-containing pseudopeptides active against retroviruses
    Patent number: 5605926
    Abstract: The present invention relates to new trifluoromethyl-containing pseudopeptides of the general formula (I) ##STR1## in which W, A, B, D, E, R.sub.1, R.sub.2 and R.sub.3 have the meaning as outlined of their making and use as pharmaceuticals.
    Type: Grant
    Filed: April 10, 1995
    Date of Patent: February 25, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter H abich, Wolfgang R oben, Jutta Hansen, Arnold Paessens
  • Substituted (2-oxo-1-benzimidazolinyl)-peperidines, process for their preparation, and use as anti-retroviral agents
    Patent number: 5571921
    Abstract: The present invention relates to substituted (2-oxo-1-benzimidazolinyl)-piperidines of the general formula (I) ##STR1## in which the substituents have the meaning indicated in the description, to processes for their preparation and to their use as antiretroviral agents.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 5, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Bender, Dieter H abich, Siegfried Raddatz, Wolfgang R oben, Hanno Wild, Jutta Hansen, Arnold Paessens
  • 6-thiono-5,6-dihydro-dibenz[B,E] azepin-11-one-11-oximes
    Patent number: 5545736
    Abstract: The invention relates to 6-thiono-dibenz[b,e]azepines, to a process for their preparation and to their use as inhibitors of reverse transcriptase and in particular as antiretroviral agents.
    Type: Grant
    Filed: January 9, 1995
    Date of Patent: August 13, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hanno Wild, Wolfgang Roeben, Arnold Paessens, J org Petersen-von Gehr