Patents by Inventor Arnold S. Leonard
Arnold S. Leonard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8647618Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.Type: GrantFiled: June 15, 2012Date of Patent: February 11, 2014Assignee: Cureium Therapeutics LLCInventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
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Publication number: 20130045525Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.Type: ApplicationFiled: June 15, 2012Publication date: February 21, 2013Applicant: BOTANIC OIL INNOVATIONS, INC.Inventors: ARNOLD S. LEONARD, DANIEL A. SALTZMAN, MARK J. MUELLER
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Patent number: 8221739Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.Type: GrantFiled: April 17, 2009Date of Patent: July 17, 2012Assignee: Botanic Oil Innovations, Inc.Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
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Patent number: 7897194Abstract: A composition of cold pressed botanic oils exhibiting antioxidant activity. The composition is a combination of at least two oils, which can be black cumin oil, black raspberry oil, red raspberry oil, pomegranate oil, pumpkin oil, or sesame, flax, chardonnay grape seed oil or any other fruit, herb, vegetable, grain or nut oil. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils. A method of producing a composition of botanic oils exhibiting antioxidant activity, comprising extracting oil in an oxygen deprived environment from fruits and vegetables and combining the extracted oils. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils.Type: GrantFiled: April 18, 2007Date of Patent: March 1, 2011Assignee: Botanic Oil Innovations, Inc.Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
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Publication number: 20100098665Abstract: A method and composition for treating cancer comprising administering to a patient an effective amount of attenuated Salmonella typhimurium containing a plasmid carrying the coding sequence encoding a truncated human interleukin-2 and optionally an oil containing a high antioxidant concentration.Type: ApplicationFiled: April 17, 2009Publication date: April 22, 2010Applicant: BOTANIC OIL INNOVATIONS, INC.Inventors: ARNOLD S. LEONARD, DANIEL A. SALTZMAN, MARK J. MUELLER
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Publication number: 20090324759Abstract: A method of treating a subject requiring immune mediation includes administering to the subject an immunostimulatory composition which contains black raspberry seed oil. Administering this composition stimulates the production of certain immune cells, including NK cells and CD8(+) lymphocytes. Administering the composition by this method also provides a method of treating, preventing, or ameliorating a condition or disease in the subject requiring enhanced immune system support.Type: ApplicationFiled: June 22, 2009Publication date: December 31, 2009Applicant: Botanic Oil Innovations, Inc.Inventors: Daniel A. Saltzman, Arnold S. Leonard, Mark J. Mueller
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Publication number: 20070243310Abstract: A composition of cold pressed botanic oils exhibiting antioxidant activity. The composition is a combination of at least two oils, which can be black cumin oil, black raspberry oil, red raspberry oil, pomegranate oil, pumpkin oil, or sesame, flax, chardonnay grape seed oil or any other fruit, herb, vegetable, grain or nut oil. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils. A method of producing a composition of botanic oils exhibiting antioxidant activity, comprising extracting oil in an oxygen deprived environment from fruits and vegetables and combining the extracted oils. The composition exhibits total antioxidant activity greater than the sum of the weighted average of the antioxidant activities of the individual oils.Type: ApplicationFiled: April 18, 2007Publication date: October 18, 2007Applicant: Botanic Oil Innovations, Inc.Inventors: Arnold S. Leonard, Daniel A. Saltzman, Mark J. Mueller
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Patent number: 5773006Abstract: The present invention provides a liposome comprising an effective immunoadjuvant amount of a lymphokine such as IL-2. Also provided is an effective antineoplastic amount of IL-2 liposomes in combination with adoptively transferred cells stimulated with anti-CD3 monoclonal antibody plus IL-2.Type: GrantFiled: April 7, 1995Date of Patent: June 30, 1998Assignee: Regents of the University of MinnesotaInventors: Peter M. Anderson, Arnold S. Leonard, Augusto C. Ochoa, Cynthia Loeffler
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Patent number: 5765231Abstract: The present invention is a face mask suitable for application to a skin surface of a person's face, the face mask comprising a plurality of facial mask segments of resilient polymeric foam, each segment conformable to at least a portion of the surface of the person's face and including a first surface, a second surface and a shaped peripheral margin, an adhesive attachment, suitable for use on the first surface of each segment and suitable for attaching the segment to the person's skin; and a decoration, suitable for application on the second surface of each segment, for decorating the face mask; wherein the plurality of facial mask segments cover substantially all of the surface of the skin of the person's face.Type: GrantFiled: March 7, 1997Date of Patent: June 16, 1998Assignee: Face Safe, Inc.Inventors: Arnold S. Leonard, Joseph G. Bilek, James L. Kruse
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Patent number: 5650152Abstract: The present invention provides a liposome comprising an effective immunoadjuvant amount of a lymphokine such as IL-2. Also provided is an effective antineoplastic amount of IL-2 liposomes in combination with adoptively transferred cells stimulated with anti-CD3 monoclonal antibody plus IL-2.Type: GrantFiled: December 10, 1993Date of Patent: July 22, 1997Assignee: Regents of the University of MinnesotaInventors: Peter M. Anderson, Arnold S. Leonard, Augusto C. Ochoa, Cynthia Loeffler
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Patent number: 5409698Abstract: The present invention provides a liposome comprising an effective immunoadjuvant amount of a lymphokine such as IL-2. Also provided is an effective antineoplastic amount of IL-2 liposomes in combination with adoptively transferred cells stimulated with anti-CD3 monoclonal antibody plus IL-2.Type: GrantFiled: October 28, 1992Date of Patent: April 25, 1995Assignee: The Regents of The University of MinnesotaInventors: Peter M. Anderson, Arnold S. Leonard, Augusto C. Ochoa, Cynthia Loeffler
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Patent number: RE38246Abstract: The present invention is a face mask suitable for application to a skin surface of a person's face, the face mask comprising a plurality of facial mask segments at least one facial mask segment of resilient polymeric foam, each segment conformable to at least a portion of the surface of the person's face and including a first surface, a second surface and a shaped peripheral margin, an adhesive attachment, suitable for use on the first surface of each segment and suitable for attaching the segment to the person's skin; and a decoration, suitable for application on the second surface of each segment, for decorating the face mask; wherein the plurality of facial mask segments cover substantially all at least one facial mask segment covers at least a portion of the surface of the skin of the person's face.Type: GrantFiled: May 4, 1999Date of Patent: September 16, 2003Inventors: Arnold S. Leonard, Joseph G. Bilek, James L. Kruse