Patents by Inventor Arnold Vogel

Arnold Vogel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antihypertensive 9-(2,N.sup.6 -disubstituted adenyl) ribofuranuronic acid derivatives
    Patent number: 5219840
    Abstract: N.sup.6, 2-disubstituted or 2-substituted 1'-desoxy-1'-(6-amino-9-purinyl)-.beta.-D-ribofuranuronic acid amides, N-substituted amides, N,N-disubstituted amides, thioamides, N-substituted thioamides and N,N-disubstituted thioamidesare effective against raised blood pressure.
    Type: Grant
    Filed: May 1, 1991
    Date of Patent: June 15, 1993
    Assignee: Sandoz Ltd.
    Inventors: Fulvio Gadient, Arnold Vogel
  • Furanuronic acid derivatives, process for their production and their use
    Patent number: 4855288
    Abstract: 1'-desoxy-1'-(6-amino-9-purinyl)-.beta.-D-ribofuranuronic acid thioamides of formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 possess various definitions given in claim 2, are effective against raised blood pressure.
    Type: Grant
    Filed: December 14, 1987
    Date of Patent: August 8, 1989
    Assignee: Sandoz Ltd.
    Inventors: Fulvio Gadient, Arnold Vogel
  • 4-(2,1,3-benzoxadiazol and benzothiadiazol-4-4L)-1,4-dihydropyridine-3,5-dicarboxylic acid esters useful as antihypertensives
    Patent number: 4707482
    Abstract: 1,4-Dihydropyridine-3,5-dicarboxylic acid esters of formula I ##STR1## wherein the substitutents have various significances, are useful as calcium antagonists.
    Type: Grant
    Filed: December 4, 1985
    Date of Patent: November 17, 1987
    Assignee: Sandoz Ltd.
    Inventor: Arnold Vogel
  • 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydropyridazine derivatives, their production and pharmaceutical compositions
    Patent number: 4491581
    Abstract: Novel 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridazines, particularly compounds of the formula I, ##STR1## wherein COOR.sub.1 and COOR.sub.2 are the same or different carboxylic acid ester groups,R.sub.3 is H or (C.sub.1-6)alkyl andR.sub.4 is H, (C.sub.1-6)alkyl, (C.sub.3-6)alkenyl or -alkynyl, (C.sub.3-7)cycloalkyl, (C.sub.4-8)cycloalkylalkyl, (C.sub.7-9)phenylalkyl or (C.sub.9-12) phenylalkenyl, the phenyl ring being unsubstituted or mono-, di- or trisubstituted independently by halogen, OH, (C.sub.1-4)alkyl or -alkoxy,for the treatment of coronary insufficiency, spasms in smooth muscles, hypertension or cerebrovascular insufficiency.
    Type: Grant
    Filed: October 28, 1982
    Date of Patent: January 1, 1985
    Assignee: Sandoz Ltd.
    Inventor: Arnold Vogel