Patents by Inventor Arnold Wishnia

Arnold Wishnia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6593144
    Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: July 15, 2003
    Assignees: The Trustees of Princeton University, The Research Foundation of State University of New York
    Inventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
  • Patent number: 6241966
    Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: June 5, 2001
    Assignees: The Trustees of Princeton University, The Research Foundation of State University of New York
    Inventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
  • Publication number: 20010000726
    Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.
    Type: Application
    Filed: December 19, 2000
    Publication date: May 3, 2001
    Inventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
  • Patent number: 6123919
    Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.
    Type: Grant
    Filed: June 24, 1999
    Date of Patent: September 26, 2000
    Assignees: The Trustees of Princeton University, The Research Foundation of State University of New York
    Inventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
  • Patent number: 5789921
    Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 4, 1998
    Assignees: The Research Foundation of State University of New York, The Trustees of Princeton University
    Inventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
  • Patent number: 5785953
    Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.
    Type: Grant
    Filed: June 17, 1996
    Date of Patent: July 28, 1998
    Assignees: The Trustees of Princeton University, The Research Foundation of State University of New York
    Inventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
  • Patent number: 5545396
    Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.
    Type: Grant
    Filed: April 8, 1994
    Date of Patent: August 13, 1996
    Assignees: The Research Foundation of State University of New York, The Trustees of Princeton University Office of Research and Project Administration
    Inventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia