Patents by Inventor Arnold Wishnia
Arnold Wishnia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6593144Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: December 19, 2000Date of Patent: July 15, 2003Assignees: The Trustees of Princeton University, The Research Foundation of State University of New YorkInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
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Patent number: 6241966Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: March 18, 1998Date of Patent: June 5, 2001Assignees: The Trustees of Princeton University, The Research Foundation of State University of New YorkInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
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Publication number: 20010000726Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: ApplicationFiled: December 19, 2000Publication date: May 3, 2001Inventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
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Patent number: 6123919Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: June 24, 1999Date of Patent: September 26, 2000Assignees: The Trustees of Princeton University, The Research Foundation of State University of New YorkInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
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Patent number: 5789921Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: June 7, 1995Date of Patent: August 4, 1998Assignees: The Research Foundation of State University of New York, The Trustees of Princeton UniversityInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
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Patent number: 5785953Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: June 17, 1996Date of Patent: July 28, 1998Assignees: The Trustees of Princeton University, The Research Foundation of State University of New YorkInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia
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Patent number: 5545396Abstract: A method of imaging a spatial distribution of a noble gas by nuclear magnetic resonance spectrometry includes detecting a spatial distribution of at least one noble gas by NMR spectrometry and generating a representation of said spatial distribution of the noble gas. The noble gas is selected from noble gas isotopes having nuclear spin, preferably Xenon-129 and/or Helium-3. The noble gas is at least thermally or equilibrium polarized and is preferably hyperpolarized, most preferably hyperpolarized by optical (laser) pumping in the presence of an alkali metal or by metastability exchange. The generation of the representation of the noble gas spatial distribution includes at least one dimension, preferably 2 or 3 dimensions of the spatial distribution. The noble gas may be imaged according to the invention in chemical or biological systems, preferably in a human or animal subject or organ system or tissue thereof.Type: GrantFiled: April 8, 1994Date of Patent: August 13, 1996Assignees: The Research Foundation of State University of New York, The Trustees of Princeton University Office of Research and Project AdministrationInventors: Mitchell S. Albert, Dilip Balamore, Gordon D. Cates, Jr., Bastiaan Driehuys, William Happer, Brian Saam, Arnold Wishnia