Patents by Inventor Arnon Rosenthal

Arnon Rosenthal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-APOE4 ANTIGEN-BINDING PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20170218058
    Abstract: The present disclosure generally relates to antigen-binding proteins (ABPs) that specifically bind to apolipoprotein E (ApoE), compositions comprising such ABPs, methods of using such ABPs, and methods of making such ABPs. In some embodiments, the ABPs provided herein bind lipidated ApoE4. In some embodiments, the lipidated ApoE4 is within a lipoprotein particle, and the ABPs therefore bind to a lipoprotein particle comprising ApoE4. Any suitable ABP may be used. In some embodiments, the ABP is an antibody. In some embodiments, the ABP is an alternative scaffold. The ABPs provided herein may be used for the prevention or treatment of any disease, condition or disorder associated with ApoE4 expression.
    Type: Application
    Filed: January 25, 2017
    Publication date: August 3, 2017
    Inventor: Arnon Rosenthal
  • ANTI-SORTILIN ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20170210808
    Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
    Type: Application
    Filed: October 4, 2016
    Publication date: July 27, 2017
    Applicant: ALECTOR LLC
    Inventors: Arnon ROSENTHAL, Tina SCHWABE, Michael KURNELLAS
  • Anti-complement factor C1q antibodies and uses thereof
    Patent number: 9708394
    Abstract: The present invention provides anti-C1q antibodies and methods of using the same.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: July 18, 2017
    Assignee: Annexon, Inc.
    Inventors: Arnon Rosenthal, Michael Leviten
  • Anti-NGF antibodies and methods using same
    Patent number: 9708398
    Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: July 18, 2017
    Assignee: RINAT NEUROSCIENCE CORP.
    Inventors: Jaume Pons, Arnon Rosenthal
  • ANTI-COMPLEMENT FACTOR C1Q FAB FRAGMENTS AND USES THEREOF
    Publication number: 20170152309
    Abstract: The present disclosure relates generally to anti-C1q antibody Fab fragments and methods of using the same.
    Type: Application
    Filed: November 23, 2016
    Publication date: June 1, 2017
    Applicant: Annexon, Inc.
    Inventors: Ted Yednock, Sethu Sankaranarayanan, Michael Leviten, Arnon Rosenthal
  • METHODS FOR TREATING OSTEOARTHRISTIS PAIN BY ADMINISTERING A NERVE GROWTH FACTOR ANTAGONIST AND COMPOSITIONS CONTAINING THE SAME
    Publication number: 20170088610
    Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
    Type: Application
    Filed: October 6, 2016
    Publication date: March 30, 2017
    Inventors: ARNON ROSENTHAL, DAVID LOUIS SHELTON, PATRICIA ANN WALICKE
  • METHODS FOR SCREENING FOR INHIBITORS OF COMPLEMENT SERINE PROTEASES
    Publication number: 20170081700
    Abstract: The present disclosure relates to methods for screening for inhibitors of complement serine proteases by measuring the interaction of a serine protease with a molecular probe in the presence and absence of test compounds.
    Type: Application
    Filed: March 19, 2015
    Publication date: March 23, 2017
    Inventors: Arnon Rosenthal, Michael Leviten
  • ANTAGONIST ANTIBODIES DIRECTED AGAINST CALCITONIN GENE-RELATED PEPTIDE AND METHODS USING SAME
    Publication number: 20170081395
    Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Application
    Filed: May 5, 2016
    Publication date: March 23, 2017
    Inventors: Joerg Zeller, Kristian T. Poulsen, Yasmina Noubia Abdiche, Jaume Pons, Sierra Jones Collier, Arnon Rosenthal
  • ANTI-COMPLEMENT FACTOR C1Q ANTIBODIES AND USES THEREOF
    Publication number: 20160368973
    Abstract: The present invention provides anti-C1q antibodies and methods of using the same.
    Type: Application
    Filed: January 6, 2016
    Publication date: December 22, 2016
    Inventors: Arnon Rosenthal, Michael Leviten
  • HUMANIZED ANTI-COMPLEMENT FACTOR C1Q ANTIBODIES AND USES THEREOF
    Publication number: 20160355574
    Abstract: The present disclosure is directed to humanized anti-C1q antibodies and methods of using them.
    Type: Application
    Filed: November 5, 2015
    Publication date: December 8, 2016
    Inventors: Arnon Rosenthal, Michael Leviten
  • Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
    Patent number: 9498530
    Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: November 22, 2016
    Assignee: RINAT NEUROSCIENCE CORP.
    Inventors: Arnon Rosenthal, David Louis Shelton, Patricia Ann Walicke
  • METHODS OF TREATMENT FOR GUILLAIN-BARRE SYNDROME
    Publication number: 20160326237
    Abstract: This invention relates generally to methods of treatment for Guillain-Barre' Syndrome (GBS) and, more specifically, to methods involving the inhibition of the classical pathway of complement activation.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 10, 2016
    Inventors: Arnon Rosenthal, Michael Leviten, Hugh J. Willison, Rhona McGonigal
  • ANTAGONIST ANTIBODIES DIRECTED AGAINST CALCITONIN GENE-RELATED PEPTIDE AND METHODS USING SAME
    Publication number: 20160168244
    Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Application
    Filed: February 16, 2016
    Publication date: June 16, 2016
    Inventors: Joerg Zeller, Kristian T. Poulsen, Yasmina Noubia Abdiche, Jaume Pons, Sierra Jones Collier, Arnon Rosenthal
  • Methods of using anti-CGRP antagonist antibodies
    Patent number: 9365648
    Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: June 14, 2016
    Assignee: LABRYS BIOLOGICS, INC.
    Inventors: Joerg Zeller, Kristian T. Poulsen, Yasmina Noubia Abdiche, Jaume Pons, Sierra Jones Collier, Arnon Rosenthal
  • METHODS OF TREATMENT FOR ALZHEIMER'S DISEASE AND HUNTINGTON'S DISEASE
    Publication number: 20160159890
    Abstract: This invention relates generally to methods of treatment for neurodegenerative diseases such as Alzheimer's disease, Alzheimer's-related diseases, and Huntington's disease, and more specifically to methods involving the inhibition of the classical pathway of complement activation.
    Type: Application
    Filed: January 5, 2016
    Publication date: June 9, 2016
    Inventors: Arnon Rosenthal, Michael Leviten, Beth A. Stevens, Soyon Hong, Daniel Wilton
  • ANTI-NGF ANTIBODIES AND METHODS USING SAME
    Publication number: 20160152698
    Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
    Type: Application
    Filed: November 13, 2015
    Publication date: June 2, 2016
    Applicant: RINAT NEUROSCIENCE CORP.
    Inventors: Jaume PONS, Arnon ROSENTHAL
  • Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
    Patent number: 9346881
    Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: May 24, 2016
    Assignee: LABRYS BIOLOGICS, INC.
    Inventors: Joerg Zeller, Kristian T. Poulsen, Yasmina Noubia Abdiche, Jaume Pons, Sierra Jones Collier, Arnon Rosenthal
  • Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
    Patent number: 9340610
    Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: May 17, 2016
    Assignee: Rinat Neuroscience Corp.
    Inventors: Arnon Rosenthal, David Louis Shelton, Patricia Ann Walicke
  • Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
    Patent number: 9340614
    Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: May 17, 2016
    Assignee: LABRYS BIOLOGICS, INC.
    Inventors: Joerg Zeller, Kristian T. Poulsen, Yasmina Noubia Abdiche, Jaume Pons, Sierra Jones Collier, Arnon Rosenthal
  • Methods of using anti-CGRP antagonist antibodies
    Patent number: 9328168
    Abstract: The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: May 3, 2016
    Assignee: LABRYS BIOLOGICS, INC.
    Inventors: Joerg Zeller, Kristian T. Poulsen, Yasmina Noubia Abdiche, Jaume Pons, Sierra Jones Collier, Arnon Rosenthal