Patents by Inventor Arnt Tonnessen

Arnt Tonnessen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Skin and muscle-targeted gene therapy by pulsed electrical field
    Publication number: 20040092860
    Abstract: The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.
    Type: Application
    Filed: June 9, 2003
    Publication date: May 13, 2004
    Inventors: Nagendu B. Dev, Gunter A. Hofmann, Edward Nolan, Dietmar P. Rabussay, Arnt Tonnessen, Georg Widera, Lei Zhang
  • Skin and muscle-targeted gene therapy by pulsed electrical field
    Patent number: 6697669
    Abstract: The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.
    Type: Grant
    Filed: July 13, 1999
    Date of Patent: February 24, 2004
    Assignee: Genetronics, Inc.
    Inventors: Nagendu B. Dev, Gunter A. Hofmann, Edward Nolan, Dietmar P. Rabussay, Arnt Tonnessen, Georg Widera, Lei Zhang
  • Skin and muscle-targeted gene therapy by pulsed electrical field
    Patent number: 6654636
    Abstract: The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: November 25, 2003
    Assignee: Genetronics, Inc.
    Inventors: Nagendu B. Dev, Gunter A. Hofmann, Edward Nolan, Dietmar P. Rabussay, Arnt Tonnessen, Georg Widera, Lei Zhang
  • SKIN AND MUSCLE-TARGETED GENE THERAPY BY PULSED ELECTRICAL FIELD
    Publication number: 20020099323
    Abstract: The present invention describes an in vivo method, using pulsed electric field to deliver therapeutic agents into cells of the skin and muscle for local and systemic treatments. In particular, therapeutic agents include naked or formulated nucleic acid, polypeptides and chemotherapeutic agents.
    Type: Application
    Filed: July 13, 1999
    Publication date: July 25, 2002
    Inventors: NAGENDU B. DEV, GUNTER A. HOFMANN, EDWARD NOLAN, DIETMAR P. RABUSSAY, ARNT TONNESSEN, GEORG WIDERA, LEI ZHANG
  • Apparatus and method for the delivery of drugs and genes into tissue
    Patent number: 6192270
    Abstract: An electrode assembly for an apparatus for and a method of trans-surface molecular delivery, including a non-conductive carrier having a proximal surface, a distal surface, and a plurality of through holes from the proximal surface to the distal surface, a first electrode disposed on at least a portion of the distal surface and extending through at least a portion of the plurality of through holes and onto at least a portion of the proximal surface, a second electrode disposed on at least a portion of the proximal surface and in closely spaced relation with the first electrode for engaging a tissue surface through which to apply an electric field, and an insulating barrier that is disposed on at least a portion of the proximal surface of the carrier between the first electrode and the second electrode.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: February 20, 2001
    Assignee: Genetronics, Inc.
    Inventors: Gunter A. Hofmann, Dietmar Rabussay, Arnt Tonnessen