Patents by Inventor Aron D. Rosenberg
Aron D. Rosenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180311402Abstract: Featured are a biocompatible, injectable, self-setting, cohesive, bone-bonding and remodeling calcium phosphate composite material and its use in methods of repairing defective bone, e.g., in vertebroplasty augmentation and kyphoplasty.Type: ApplicationFiled: April 25, 2018Publication date: November 1, 2018Inventors: Aliassghar N. TOFIGHI, Aron D. ROSENBERG, Tak Lung CHANG, Michael STRUNK
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Patent number: 9956313Abstract: Featured are a biocompatible, injectable, self-setting, cohesive, bone-bonding and remodeling calcium phosphate composite material and its use in methods of repairing defective bone, e.g., in vertebroplasty augmentation and kyphoplasty.Type: GrantFiled: April 18, 2016Date of Patent: May 1, 2018Assignee: Life Science Enterprises, Inc.Inventors: Aliassghar N. Tofighi, Aron D. Rosenberg, Tak Lung Chang, Michael Strunk
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Patent number: 9427715Abstract: Bone cement mixing and delivery device and methods are disclosed. The device includes a first tube/barrel (e.g., a syringe barrel) containing a bone cement powder and a second tube/barrel that can be filled with or that contains a liquid; the first and second tubes/barrels can be fluidly connected end-to-end such that there is fluid communication between the tubes/barrels. Also disclosed are methods of preparing the device for use, methods for forming a bone cement using the device, and methods and device design to extend the shelf life of the device.Type: GrantFiled: August 28, 2008Date of Patent: August 30, 2016Assignee: ETEX CorporationInventors: Robert Palazzolo, Manish Sutaria, Aliassghar N. Tofighi, Tak L. Chang, Aron D. Rosenberg
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Publication number: 20160228598Abstract: Featured are a biocompatible, injectable, self-setting, cohesive, bone-bonding and remodeling calcium phosphate composite material and its use in methods of repairing defective bone, e.g., in vertebroplasty augmentation and kyphoplasty.Type: ApplicationFiled: April 18, 2016Publication date: August 11, 2016Inventors: Aliassghar N. TOFIGHI, Aron D. ROSENBERG, Tak Lung CHANG, Michael STRUNK
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Patent number: 9314545Abstract: Featured are a biocompatible, injectable, self-setting, cohesive, bone-bonding and remodeling calcium phosphate composite material and its use in methods of repairing defective bone, e.g., in vertebroplasty augmentation and kyphoplasty.Type: GrantFiled: April 15, 2009Date of Patent: April 19, 2016Assignee: LIFE SCIENCE ENTERPRISES, INC.Inventors: Aliassghar N. Tofighi, Aron D. Rosenberg, Tak Lung Chang, Michael Strunk
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Patent number: 8545858Abstract: Porous calcium phosphate implant compositions that approximate the chemical composition of natural bone mineral are provided. In addition to calcium phosphate, the compositions include an effervescent agent to promote the formation of interconnected pores and a cohesiveness agent to maintain the shape and hardness of the hardened composition. When introduced at an implant site, the calcium phosphate compositions are remodeled into bone. Methods for using the calcium phosphate compositions, e.g., to repair or replace bone, are also provided.Type: GrantFiled: April 3, 2012Date of Patent: October 1, 2013Assignee: Etex CorporationInventors: Aron D. Rosenberg, Laurent D. Gillès de Pélichy, Shrikar Bondre, Michael Strunk
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Patent number: 8454988Abstract: Osteogenic bone implant compositions that approximate the chemical composition of natural bone are provided. The organic component of these implant compositions is osteoinductive despite the presence of the inorganic component and, further, is present in an amount sufficient to maximize the regenerative capabilities of the implant without compromising its formability and mechanical strength. The composition may be an osteoinductive powder, including demineralized bone matrix (DBM) particles, a calcium phosphate powder, and, optionally, a biocompatible cohesiveness agent. The powder may be combined with a physiologically-acceptable fluid to produce a formable, osteoinductive paste that self-hardens to form a poorly crystalline apatitic (PCA) calcium phosphate having significant compressive strength. The bone implant materials retain their cohesiveness when introduced at an implant site and are remodeled into bone in vivo.Type: GrantFiled: January 23, 2008Date of Patent: June 4, 2013Assignee: Etex CorporationInventors: Aron D. Rosenberg, Laurent D. Gilles de Pelichy, Daniel Egan, Aliassghar N. Tofighi, Youngmi M. Lee
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Publication number: 20120282301Abstract: Porous calcium phosphate implant compositions that approximate the chemical composition of natural bone mineral are provided. In addition to calcium phosphate, the compositions include an effervescent agent to promote the formation of interconnected pores and a cohesiveness agent to maintain the shape and hardness of the hardened composition. When introduced at an implant site, the calcium phosphate compositions are remodeled into bone. Methods for using the calcium phosphate compositions, e.g., to repair or replace bone, are also provided.Type: ApplicationFiled: April 3, 2012Publication date: November 8, 2012Applicant: Etex CorporationInventors: Aron D. Rosenberg, Laurent D. Gillès de Pélichy, Shrikar Bondre, Michael Strunk
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Patent number: 8221781Abstract: Osteogenic bone implant compositions that approximate the chemical composition of natural bone are provided. The organic component of these implant compositions is osteoinductive despite the presence of the inorganic component and, further, is present in an amount sufficient to maximize the regenerative capabilities of the implant without compromising its formability and mechanical strength. The composition may be an osteoinductive powder, including demineralized bone matrix (DBM) particles, a calcium phosphate powder, and, optionally, a biocompatible cohesiveness agent. The powder may be combined with a physiologically-acceptable fluid to produce a formable, osteoinductive paste that self-hardens to form a poorly crystalline apatitic (PCA) calcium phosphate having significant compressive strength. The bone implant materials retain their cohesiveness when introduced at an implant site and are remodeled into bone in vivo.Type: GrantFiled: April 12, 2004Date of Patent: July 17, 2012Assignee: Etex CorporationInventors: Aron D. Rosenberg, Laurent D. Gilles de Pelichy, Daniel Egan, Aliassghar N. Tofighi, Dosuk D. Lee
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Patent number: 8216359Abstract: The invention features delayed-setting calcium phosphate pastes which are useful for the preparation of delivery vehicles for biologically active agents, useful for the treatment of orthopedic conditions and can be stored for long periods without prematurely setting.Type: GrantFiled: April 14, 2005Date of Patent: July 10, 2012Assignee: ETEX CorporationInventors: Dosuk D. Lee, Youngmi M. Lee, legal representative, Aron D. Rosenberg, Laurent D. Gilles De Pelichy, Manish Sutaria, Aliassghar N. Tofighi
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Patent number: 8147860Abstract: Porous calcium phosphate implant compositions that approximate the chemical composition of natural bone mineral are provided. In addition to calcium phosphate, the compositions include an effervescent agent to promote the formation of interconnected pores and a cohesiveness agent to maintain the shape and hardness of the hardened composition. When introduced at an implant site, the calcium phosphate compositions are remodeled into bone. Methods for using the calcium phosphate compositions, e.g., to repair or replace bone, are also provided.Type: GrantFiled: December 6, 2005Date of Patent: April 3, 2012Assignee: ETEX CorporationInventors: Aron D. Rosenberg, Laurent D. Gillès de Pélichy, Shrikar Bondre, Michael Strunk
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Publication number: 20110224675Abstract: Featured are a biocompatible, injectable, self-setting, cohesive, bone-bonding and remodeling calcium phosphate composite material and its use in methods of repairing defective bone, e.g., in vertebroplasty augmentation and kyphoplasty.Type: ApplicationFiled: April 15, 2009Publication date: September 15, 2011Inventors: Aliassghar N. Tofighi, Aron D. Rosenberg, Tak Lung Chang, Michael Strunk
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Publication number: 20110112543Abstract: Bone cement mixing and delivery device and methods are disclosed. The device includes a first tube/barrel (e.g., a syringe barrel) containing a bone cement powder and a second tube/barrel that can be filled with or that contains a liquid; the first and second tubes/barrels can be fluidly connected end-to-end such that there is fluid communication between the tubes/barrels. Also disclosed are methods of preparing the device for use, methods for forming a bone cement using the device, and methods and device design to extend the shelf life of the device.Type: ApplicationFiled: August 28, 2008Publication date: May 12, 2011Inventors: Robert Palazzolo, Manish Sutaria, Aliassghar N. Tofighi, Tak L. Chang, Aron D. Rosenberg
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Patent number: 7582309Abstract: Demineralized bone matrix fibers and a demineralized bone matrix composition are provided. The demineralized bone matrix fibers have an average fiber length in the range from about 250 ?m to about 2 mm and an aspect ratio of greater than about 4. The demineralized bone matrix composition includes demineralized bone matrix fibers and a biocompatible liquid in an amount to produce a coherent, formable mass. The formable mass retains its cohesiveness when immersed in a liquid. Methods for making the demineralized bone matrix fibers and composition are also provided.Type: GrantFiled: November 15, 2002Date of Patent: September 1, 2009Assignee: Etex CorporationInventors: Aron D. Rosenberg, Laurent Gilles de Pelichy
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Publication number: 20080188946Abstract: Osteogenic bone implant compositions that approximate the chemical composition of natural bone are provided. The organic component of these implant compositions is osteoinductive despite the presence of the inorganic component and, further, is present in an amount sufficient to maximize the regenerative capabilities of the implant without compromising its formability and mechanical strength. The composition may be an osteoinductive powder, including demineralized bone matrix (DBM) particles, a calcium phosphate powder, and, optionally, a biocompatible cohesiveness agent. The powder may be combined with a physiologically-acceptable fluid to produce a formable, osteoinductive paste that self-hardens to form a poorly crystalline apatitic (PCA) calcium phosphate having significant compressive strength. The bone implant materials retain their cohesiveness when introduced at an implant site and are remodeled into bone in vivo.Type: ApplicationFiled: January 23, 2008Publication date: August 7, 2008Applicant: Etex CorporationInventors: Aron D. Rosenberg, Laurent D. Gilles de Pelichy, Daniel Egan, Aliassghar N. Tofighi, Dosuk D. Lee, Youngmi M. Lee
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Publication number: 20040097612Abstract: Demineralized bone matrix fibers and a demineralized bone matrix composition are provided. The demineralized bone matrix fibers have an average fiber length in the range from about 250 &mgr;m to about 2 mm and an aspect ratio of greater than about 4. The demineralized bone matrix composition includes demineralized bone matrix fibers and a biocompatible liquid in an amount to produce a coherent, formable mass. The formable mass retains its cohesiveness when immersed in a liquid. Methods for making the demineralized bone matrix fibers and composition are also provided.Type: ApplicationFiled: November 15, 2002Publication date: May 20, 2004Applicant: Etex CorporationInventors: Aron D. Rosenberg, Laurent Gilles de Pelichy