Patents by Inventor Aron M. Knickerbocker

Aron M. Knickerbocker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Strain of Saccharomyces cerevisiae expressing the gene encoding potassium transporter minK
    Patent number: 5620892
    Abstract: A modified Saccharomyces cerevisiae cell, wherein the cell expresses minK but does not express TRK1 and TRK2. Also disclosed is a process for detecting modulators of minK, which comprises (a) treating such modified Saccharomyces cerevisiae cells with a test compound, (b) assessing growth in the presence of a test compound and (c) determining an increase or decrease in potassium uptake into the Saccharomyces cerevisiae cells. MinK inhibitors are useful anti-arrhythmic or antifibrillatory agents; activators, anti-ischemic agents.
    Type: Grant
    Filed: September 7, 1993
    Date of Patent: April 15, 1997
    Assignee: Bristol-Myers Squibb Company
    Inventors: Stephen E. Kurtz, Aron M. Knickerbocker, John R. McCullough