Patents by Inventor Arrico De Benedetti

Arrico De Benedetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid vector and method resulting in protein overproduction by eukaryotic cells
    Patent number: 5646009
    Abstract: A hybrid vector carrying a first and second DNA segments operationally linked thereto, the first DNA segment encoding a protein capable of cross-linking to the cap structure of mRNA and mediating ribosome-binding, and the second DNA segment encoding a polypeptide or protein, the vector being capable of replication, transcription and translation to express the factor and the polypeptide or protein upon transformation of a eukaryotic host, and the polypeptide or protein being expressed at a level higher than the level of expression thereof in the absence of the first DNA segment. A eukaryotic host is transformed with this hybrid vector. Also disclosed is a method of increasing the synthesis of a polypeptide or protein in a eukaryotic host cell.
    Type: Grant
    Filed: January 19, 1994
    Date of Patent: July 8, 1997
    Assignee: The University of Kentucky Research Foundation
    Inventors: Robert E. Rhoads, Arrico De Benedetti