Patents by Inventor Arshad Quadri
Arshad Quadri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170035562Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.Type: ApplicationFiled: October 7, 2016Publication date: February 9, 2017Applicant: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Publication number: 20170020695Abstract: A percutaneous heart valve for deployment within a body cavity is described. The percutaneous heart valve includes an expandable frame having a plurality of cells adapted for allowing the frame to expand and collapse. A one-way valve is positioned within the expandable frame. The frame includes a proximal anchoring portion and a distal anchoring portion. The distal anchoring portion includes a plurality of distal anchors, each distal anchor having at least a portion positioned radially outwardly from the frame and extending in a direction that is substantially parallel with a longitudinal axis. The distal anchors preferably bend radially outwardly before bending to extend toward the proximal anchoring portion. Radial expansion of the frame causes the proximal and distal anchoring portions to move closer together for capturing body tissue therebetween, thereby anchoring the percutaneous heart valve to the body tissue.Type: ApplicationFiled: October 10, 2016Publication date: January 26, 2017Applicant: Edwards Lifesciences CardiAQ LLCInventor: Arshad Quadri
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Patent number: 9532869Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.Type: GrantFiled: June 24, 2014Date of Patent: January 3, 2017Assignee: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Publication number: 20160331532Abstract: A method for delivering a heart valve prosthesis to a native valve annulus comprises expanding an expandable frame at the native valve annulus and positioning a replacement heart valve within the expandable frame. The expandable frame preferably includes a first anchoring portion that is positioned on a first side of the native valve annulus and a second anchoring portion that is positioned on a second side of the native valve annulus. The first anchoring portion engages tissue on the first side of the native valve annulus and the second anchoring portion engages tissue on the second side of the native valve annulus for securing the expandable frame to the native valve annulus. The replacement heart valve comprises a plurality of leaflets for replacing the function of the native valve.Type: ApplicationFiled: July 27, 2016Publication date: November 17, 2016Applicant: Edwards Lifesciences CardiAQ LLCInventor: Arshad Quadri
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Publication number: 20160331531Abstract: A heart valve includes a valve body made of a flexible material such as pericardium. The valve body is made of two layers of material, an outer layer, and an inner layer that defines a plurality of leaflets. The leaflets of the inner layer are attached to the outer layer. In some embodiments the valve body is made by cutting a single piece of flat source tissue, folding the cut tissue and forming it into a tubular pattern having the inner and outer layers. The multi-layer valve body can be mounted on a stent for delivery within a patient's heart.Type: ApplicationFiled: July 25, 2016Publication date: November 17, 2016Applicant: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Patent number: 9486336Abstract: A prosthesis can be deployed within a body cavity. The prosthesis can include an expandable frame, a plurality of proximal prongs, and a plurality of distal prongs. Each prong of the proximal and distal pluralities is connected to the frame. When the frame is expanded, the ends of the prongs are positioned radially outward from the frame. The frame is configured such that radial expansion of the frame causes the ends of the proximal prongs and the ends of the distal prongs to draw closer together.Type: GrantFiled: January 22, 2013Date of Patent: November 8, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventor: Arshad Quadri
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Publication number: 20160317301Abstract: Devices, systems and methods are described herein a prosthesis for implantation within a lumen or body cavity and delivery systems for delivering the prosthesis to a location for implantation. A delivery system can include a plurality of components, including a flexible nose cone, multi-layer sheath, and pre-compressed shaft, which can be moveable relative to each other.Type: ApplicationFiled: April 28, 2016Publication date: November 3, 2016Applicant: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz, Yen Liao, Julio Cesar Sanchez, Alexander H. Cooper, Glen T. Rabito, Siddharth Vad, Luca Pesce, Kevin M. Stewart, David Robert Landon
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Patent number: 9480560Abstract: A method is disclosed of enhancing the securing of an intralumenal frame assembly to intralumenal tissue at an in situ target location. The method can comprise delivering an intralumenal frame assembly mounted on a delivery device to a treatment location. The intralumenal frame can be deployed to expand in situ so that anchors on the intralumenal frame atraumatically grasp intralumenal tissue at the target location. A radially inward force can be exerted on the frame assembly to cause the proximal and distal anchors to grasp more forcefully the intralumenal tissue.Type: GrantFiled: January 31, 2013Date of Patent: November 1, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz, Robrecht Michiels
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Patent number: 9456896Abstract: A prosthesis can be configured to be deployed within a body cavity. The prosthesis has an expandable frame, a plurality of proximal anchors, and a plurality of distal anchors, where the various anchors are connected to the frame. Radial expansion of the frame can cause the ends of the proximal anchors and the ends of the distal anchors to draw closer together.Type: GrantFiled: January 22, 2013Date of Patent: October 4, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Patent number: 9433514Abstract: A method of securing a prosthesis atraumatically to body tissue can include one or more of the following steps. A prosthesis can be delivered into a patient. The prosthesis may include an expandable frame. The frame can be expanded within a body cavity of the patient. Expansion of the frame can causes respective ends of both proximal prongs and distal prongs to draw closer together to grasp native tissue between the respective ends of the proximal prongs and distal prongs.Type: GrantFiled: January 9, 2012Date of Patent: September 6, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventor: Arshad Quadri
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Publication number: 20160143733Abstract: A replacement heart valve has an expandable frame configured to engage a native valve annulus and a valve body mounted to the expandable frame. The valve body can have a plurality of valve leaflets configured to open to allow flow in a first direction and engage one another so as to close and prevent flow in a second direction, the second direction being opposite the first direction.Type: ApplicationFiled: January 29, 2016Publication date: May 26, 2016Inventors: Arshad Quadri, Jeremy Brent Ratz, Robrecht Michiels
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Publication number: 20160135948Abstract: A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state.Type: ApplicationFiled: January 22, 2016Publication date: May 19, 2016Applicant: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Patent number: 9339378Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.Type: GrantFiled: January 31, 2013Date of Patent: May 17, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Patent number: 9339380Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.Type: GrantFiled: February 21, 2014Date of Patent: May 17, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Patent number: 9339379Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.Type: GrantFiled: January 31, 2013Date of Patent: May 17, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Patent number: 9339377Abstract: A prosthesis can be configured to be deployed within a body cavity. The prosthesis has an expandable frame, a plurality of proximal anchors, and a plurality of distal anchors, where the various anchors are connected to the frame. Radial expansion of the frame can cause the ends of the proximal anchors and the ends of the distal anchors to draw closer together.Type: GrantFiled: March 5, 2013Date of Patent: May 17, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Patent number: 9333074Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.Type: GrantFiled: January 16, 2015Date of Patent: May 10, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Patent number: 9333073Abstract: A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant can be verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.Type: GrantFiled: November 11, 2014Date of Patent: May 10, 2016Assignee: Edwards Lifesciences CardiAQ LLCInventors: Arshad Quadri, J. Brent Ratz
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Publication number: 20150342736Abstract: Disclosed herein are embodiments of a prosthesis and delivery device, as well as methods of use. The delivery device can be composed of an inner retention assembly configured to carry an expandable prosthesis to an in situ target location. The inner retention assembly can slide within an outer elongate hollow member which can cover the expandable prosthesis. The outer elongate hollow member can further be longitudinally collapsed into a receiving member located at the distal end of the outer elongate hollow member.Type: ApplicationFiled: May 28, 2015Publication date: December 3, 2015Inventors: Glen Rabito, Julio Cesar Sanchez, Arshad Quadri, J. Brent Ratz, Luca Pesce, Yen Liao
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Publication number: 20150305864Abstract: A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. The valve body can include a leaflet portion and possibly a skirt portion. A portion of the frame has a foreshortening portion configured to longitudinally expand when urged to a radially compacted state and longitudinally contract when urged to a radially expanded state. In one embodiment the valve skirt is attached to the frame so that it can adapt to changes in the length of the frame. A delivery device in some embodiments can use one or more coverings, such as sheaths, to controllably release the replacement heart valve at a native heart valve.Type: ApplicationFiled: May 1, 2015Publication date: October 29, 2015Inventors: Arshad Quadri, J. Brent Ratz