Patents by Inventor Artemis G. Hatzigeorgiou

Artemis G. Hatzigeorgiou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND SYSTEMS FOR IDENTIFYING MICRO-RNA TARGETS AND SYNTHESIZING NOVEL MICRO-RNAS AND USES OF THE SAME
    Publication number: 20140106351
    Abstract: Method of identifying a microRNA-recognition element and of generating microRNAs are disclosed. System and computer programs for performing such methods are disclosed. Recombinant nucleic acid molecule comprising a heterologous coding sequences and one or more MREs are also disclosed as are isolated nucleic acid molecule comprising one or more MRE sequences and being free of a coding sequence operably linked to regulatory elements. MicroRNA generated by a methods of the invention and the use of the microRNAs to downregulate gene expression are disclosed.
    Type: Application
    Filed: September 9, 2013
    Publication date: April 17, 2014
    Applicant: The Trustees Of The University of Pennsylvania
    Inventors: Artemis G. Hatzigeorgiou, Zissimos Mourelatos
  • Methods and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same
    Patent number: 8532937
    Abstract: Method of identifying a microRNA-recognition element and of generating microRNAs are disclosed. System and computer programs for performing such methods are disclosed. Recombinant nucleic acid molecule comprising a heterologous coding sequences and one or more MREs are also disclosed as are isolated nucleic acid molecule comprising one or more MRE sequences and being free of a coding sequence operably linked to regulatory elements. MicroRNA generated by a methods of the invention and the use of the microRNAs to downregulate gene expression are disclosed.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: September 10, 2013
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Artemis G. Hatzigeorgiou, Zissimos Mourelatos
  • METHODS AND SYSTEMS FOR IDENTIFYING MICRO-RNA TARGETS AND SYNTHESIZING NOVEL MICRO-RNAS AND USES OF THE SAME
    Publication number: 20120244618
    Abstract: Method of identifying a microRNA-recognition element and of generating microRNAs are disclosed. System and computer programs for performing such methods are disclosed. Recombinant nucleic acid molecule comprising a heterologous coding sequences and one or more MREs are also disclosed as are isolated nucleic acid molecule comprising one or more MRE sequences and being free of a coding sequence operably linked to regulatory elements. MicroRNA generated by a methods of the invention and the usr of the microRNAs to downregulate gene expression are disclosed.
    Type: Application
    Filed: February 22, 2012
    Publication date: September 27, 2012
    Inventors: Artemis G. Hatzigeorgiou, Zissimos Mourelatos
  • Method and systems for identifying micro-RNA targets and synthesizing novel micro-RNAs and uses of the same
    Patent number: 8145436
    Abstract: Method of identifying a microRNA-recognition element and of generating microRNAs are disclosed. System and computer programs for performing such methods are disclosed. Recombinant nucleic acid molecule comprising a heterologous coding sequences and one or more MREs are also disclosed as are isolated nucleic acid molecule comprising one or more MRE sequences and being free of a coding sequence operably linked to regulatory elements. MicroRNA generated by a methods of the invention and the use of the microRNAs to downregulate gene expression are disclosed.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: March 27, 2012
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Artemis G. Hatzigeorgiou, Zissimos Mourelatos