Abstract: Provided is a bone joining device suitable for joining a first bone piece to a second bone piece. Also provided is a method of joining a first bone piece with a second bone piece in a living mammal. The method comprises inserting the above bone joining device between the first bone piece and the second bone piece.

Abstract: A plate for adjusting the position of a first piece of bone with respect to a second piece of bone, comprising a first section comprising a first upper exterior surface, a first lower exterior surface, a first outer edge, a first distal end, a first coupling end across the first section from the first distal end, at least one first section bone screw hole, and a first bone screw in the at least one first section bone screw hole, a second section comprising a second upper exterior surface, a second lower exterior surface, a second outer edge, a second distal end, a second coupling end across the second section from the second distal end, at least one second section bone screw hole, and a second bone screw in the at least one second section bone screw hole, and a gear deposed between the first section and the second section.

Abstract: Provided is a bone joining device suitable for joining a first bone piece to a second bone piece. Also provided is a method of joining a first bone piece with a second bone piece in a living mammal. The method comprises inserting the above bone joining device between the first bone piece and the second bone piece.

Abstract: Disclosed is a delivery system for an intervertebral spacer and a bone grafting material in the form of a unitary device which comprises a spacer disengagingly attached to a hollow handle. The handle comprises a chamber and bone grafting material-advancing means within the chamber for introducing the bone grafting material from the chamber into and around the spacer and the intervertebral spaces. The handle is disengageable from the spacer after serving its purpose of facilitating placement of the spacer and the discharge of the bone grafting material into the spacer and the intervertebral space. The intervertebral spacer implant portion is attached to the handle portion at the exit port of the chamber, the point of attachment constituting the entry port of the intervertebral spacer implant portion.

Abstract: A multipart intervertebral implant is provided which includes an implant portion and an implant extender portion. The implant portion and the implant extender portion can be fastened together using any known fastening means including pins, interlocking structure (e.g., dovetail, tongue and groove, etc.), adhesives, etc. The size of the implant extender portion can be selected during a surgical procedure to provide an implant suitable for a particular intervertebral receiving bed. An intervertebral implant is also provided which may be formed from a multiplicity of implant sections which are fastened together to provide an implant having a desired length. Implants having surface configurations which more closely correspond to the configuration of vertebral endplates are also provided.

Abstract: This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices. In one particular embodiment, methods for enhancing cellular functions on a surface of a medical device implant are disclosed which generally comprise providing a medical device implant comprising a plurality of nanofibers (e.g., nanowires) thereon and exposing the medical device implant to cells such as osteoblasts.

Abstract: A device for repairing an anatomical defect such as a patent foramen ovale possesses spring-like characteristics enabling it to be stored within, and discharged from, the distal end of a catheter when the device is in the compressed state and to assume a defect-occluding configuration when the device is in the expanded, or noncompressed, state.

Abstract: This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices.

Abstract: An occlusion device for occluding an abnormal opening includes a body configured to receive expansion medium so as to expand to a deployed position, in which the periphery of the body sealingly presses against the wall of the abnormal opening.

Abstract: A multipart intervertebral implant is provided which includes an implant portion and an implant extender portion. The implant portion and the implant extender portion can be fastened together using any known fastening means including pins, interlocking structure (e.g., dovetail, tongue and groove, etc.), adhesives, etc. The size of the implant extender portion can be selected during a surgical procedure to provide an implant suitable for a particular intervertebral receiving bed. An intervertebral implant is also provided which may be formed from a multiplicity of implant sections which are fastened together to provide an implant having a desired length. Implants having surface configurations which more closely correspond to the configuration of vertebral endplates are also provided.

Abstract: There is provided a combined two-part intervertebral implant (10) configured to restore the spacing between adjacent vertebrae. The implant (10) generally includes a spacer ring (12) having upper and lower vertebral engaging surfaces and a bore for receipt of a locking element (14). The implant (10) further includes a locking element (14) which is engageable within the spacer ring (12) and has a diameter or height greater than the thickness of the spacer ring. In one embodiment, the spacer ring (12) may be formed as a C-shaped element (16). In an alternative embodiment, the spacer ring may be formed as an intact ring (42) having a side bore (44) for receipt of the locking element. One or both parts of the implant (10) may be partially or wholly surface demineralized to provide a flexible surface on implant. A method of using the spacer ring (12) and locking element (14) to secure the assembled implant between adjacent vertebrae is also disclosed.

Abstract: A multipart intervertebral implant is provided which includes an implant portion and an implant extender portion. The implant portion and the implant extender portion can be fastened together using any known fastening means including pins, interlocking structure (e.g., dovetail, tongue and groove, etc.), adhesives, etc. The size of the implant extender portion can be selected during a surgical procedure to provide an implant suitable for a particular intervertebral receiving bed. An intervertebral implant is also provided which may be formed from a multiplicity of implant sections which are fastened together to provide an implant having a desired length. Implants having surface configurations which more closely correspond to the configuration of vertebral endplates are also provided.

Abstract: There is provided a combined two-part intervertebral implant configured to restore the spacing between adjacent vertebrae. The implant generally includes a spacer ring having upper and lower vertebral engaging surfaces and a bore for receipt of a locking element. The implant further includes a locking element which is engagable within the spacer ring and has a diameter or height greater than the thickness of the spacer ring. In one embodiment, the spacer ring may be formed as a C-shaped element. In an alternative embodiment, the spacer ring may be formed as an intact ring having a side bore for receipt of the locking element. One or both parts of the implant may be partially or wholly surface demineralized to provide a flexible surface on implant. A method of using the spacer ring and locking element to secure the assembled implant between adjacent vertebrae is also disclosed.

Abstract: A multipart intervertebral implant is provided which includes an implant portion and an implant extender portion. The implant portion and the implant extender portion can be fastened together using any known fastening means including pins, interlocking structure (e.g., dovetail, tongue and groove, etc.), adhesives, etc. The size of the implant extender portion can be selected during a surgical procedure to provide an implant suitable for a particular intervertebral receiving bed. An intervertebral implant is also provided which may be formed from a multiplicity of implant sections which are fastened together to provide an implant having a desired length. Implants having surface configurations which more closely correspond to the configuration of vertebral endplates are also provided.

Abstract: A prosthetic heart valve is disclosed which has a rigid shoulder with staple receiving means. Using the staple receiving means of the shoulder, the heart valve may be secured within the heart by stapling the shoulder of the prosthesis to the patient's tissue. Such a prosthesis is advantageous in that it may be secured in a much shorter time period than conventional valves thereby reducing the risks and complications of surgery.